13983


Mus musculus (NCBI)
regulationbindingtranscriptioncellreceptoractivityrnapolymeraseiidevelopmentproliferationsignalingpathwaydnaresponseneuronsteroidhormonefactorsequence-specificdna-templatedapoptoticestrogenprocessintracellularbehaviorepithelialdna-bindingdeathprostate

Features
Gene ID: 13983
  
Biological name :
  
Synonyms : ER[b]|ERbeta|Estrb / Esr2 / estrogen receptor 2 (beta)
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1426103_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - NP_034287.3
RefSeq - NP_997590.1
RefSeq - 46877094
RefSeq - 46877096
RefSeq - NC_000078.6
RefSeq - NR_104386.1
RefSeq - NM_010157.3
RefSeq - NM_207707.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000021055 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentresponse to stresslocalization of cellmovement of cell or subcellular componentcellular developmental processsystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathmulticellular organism reproductionmuscle cell proliferationepithelial cell proliferationregulation of molecular functiondevelopmental maturationregulation of biological qualityfeeding behaviornitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentresponse to stresslocalization of cellmovement of cell or subcellular componentcellular developmental processsystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathmulticellular organism reproductionmuscle cell proliferationepithelial cell proliferationregulation of molecular functiondevelopmental maturationregulation of biological qualityfeeding behaviornitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentresponse to stresslocalization of cellmovement of cell or subcellular componentcellular developmental processsystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathmulticellular organism reproductionmuscle cell proliferationepithelial cell proliferationregulation of molecular functiondevelopmental maturationregulation of biological qualityfeeding behaviornitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentresponse to stresslocalization of cellmovement of cell or subcellular componentcellular developmental processsystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathmulticellular organism reproductionmuscle cell proliferationepithelial cell proliferationregulation of molecular functiondevelopmental maturationregulation of biological qualityfeeding behaviornitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentresponse to stresslocalization of cellmovement of cell or subcellular componentcellular developmental processsystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathmulticellular organism reproductionmuscle cell proliferationepithelial cell proliferationregulation of molecular functiondevelopmental maturationregulation of biological qualityfeeding behaviornitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentresponse to stresslocalization of cellmovement of cell or subcellular componentcellular developmental processsystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathmulticellular organism reproductionmuscle cell proliferationepithelial cell proliferationregulation of molecular functiondevelopmental maturationregulation of biological qualityfeeding behaviornitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentresponse to stresslocalization of cellmovement of cell or subcellular componentcellular developmental processsystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathmulticellular organism reproductionmuscle cell proliferationepithelial cell proliferationregulation of molecular functiondevelopmental maturationregulation of biological qualityfeeding behaviornitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentresponse to stresslocalization of cellmovement of cell or subcellular componentcellular developmental processsystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathmulticellular organism reproductionmuscle cell proliferationepithelial cell proliferationregulation of molecular functiondevelopmental maturationregulation of biological qualityfeeding behaviornitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentresponse to stresslocalization of cellmovement of cell or subcellular componentcellular developmental processsystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathmulticellular organism reproductionmuscle cell proliferationepithelial cell proliferationregulation of molecular functiondevelopmental maturationregulation of biological qualityfeeding behaviornitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentresponse to stresslocalization of cellmovement of cell or subcellular componentcellular developmental processsystem processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathmulticellular organism reproductionmuscle cell proliferationepithelial cell proliferationregulation of molecular functiondevelopmental maturationregulation of biological qualityfeeding behaviornitrognitrogen compound metabolic processbiosynbiosynthetic processcellulcellular metabolic processprimarprimary metabolic processorganiorganic substance metabolic processanatomanatomical structure developmentresponresponse to stresslocalilocalization of cellmovememovement of cell or subcellular componentcellulcellular developmental processsystemsystem processcell ccell communicationresponresponse to endogenous stimulusresponresponse to chemicalcellulcellular response to stimuluscell dcell deathmulticmulticellular organism reproductionmusclemuscle cell proliferationepitheepithelial cell proliferationregularegulation of molecular functiondevelodevelopmental maturationregularegulation of biological qualityfeedinfeeding behavior
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingprotein bindingdrug bindingion bindinghormone bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingprotein bindingdrug bindingion bindinghormone bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingprotein bindingdrug bindingion bindinghormone bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingprotein bindingdrug bindingion bindinghormone bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingprotein bindingdrug bindingion bindinghormone bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingprotein bindingdrug bindingion bindinghormone bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingprotein bindingdrug bindingion bindinghormone bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingprotein bindingdrug bindingion bindinghormone bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingprotein bindingdrug bindingion bindinghormone bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingprotein bindingdrug bindingion bindinghormone bindingchromatin bindingorganic cyclicorganic cyclic compound bindingheterocyclic cheterocyclic compound bindingDNA-binding trDNA-binding transcription factor activitysignaling recesignaling receptor activitylipid bindinglipid bindingprotein bindinprotein bindingdrug bindingdrug bindingion bindingion bindinghormone bindinhormone bindingchromatin bindchromatin binding
cellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellcellorganelleorganellemembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0001662 behavioral fear response ISO
 biological_processGO:0001764 neuron migration IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0007611 learning or memory ISO
 biological_processGO:0008285 negative regulation of cell proliferation IGI
 biological_processGO:0008628 hormone-mediated apoptotic signaling pathway IMP
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway ISO
 biological_processGO:0030520 intracellular estrogen receptor signaling pathway ISO
 biological_processGO:0033574 response to testosterone ISO
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043523 regulation of neuron apoptotic process ISO
 biological_processGO:0044849 estrous cycle ISO
 biological_processGO:0045742 positive regulation of epidermal growth factor receptor signaling pathway ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0048521 negative regulation of behavior ISO
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation ISO
 biological_processGO:0050680 negative regulation of epithelial cell proliferation ISO
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 biological_processGO:0060011 Sertoli cell proliferation ISO
 biological_processGO:0060065 uterus development IGI
 biological_processGO:0060068 vagina development IGI
 biological_processGO:0060548 negative regulation of cell death ISO
 biological_processGO:0060740 prostate gland epithelium morphogenesis IMP
 biological_processGO:0060743 epithelial cell maturation involved in prostate gland development IMP
 biological_processGO:0060766 negative regulation of androgen receptor signaling pathway IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071392 cellular response to estradiol stimulus ISO
 biological_processGO:0097755 positive regulation of blood vessel diameter ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:2000252 negative regulation of feeding behavior ISO
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005929 cilium ISO
 cellular_componentGO:0032993 protein-DNA complex ISO
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043204 perikaryon ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity ISO
 molecular_functionGO:0005496 steroid binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding ISO
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0030284 estrogen receptor activity ISO
 molecular_functionGO:0034056 estrogen response element binding ISO
 molecular_functionGO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding ISO
 molecular_functionGO:0042562 hormone binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042975 peroxisome proliferator activated receptor binding ISO
 molecular_functionGO:0043565 sequence-specific DNA binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1903924 estradiol binding ISO
 molecular_functionGO:1990239 steroid hormone binding ISO
 molecular_functionGO:1990841 promoter-specific chromatin binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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