1436


Homo sapiens (NCBI)

Features
Gene ID: 1436
  
Biological name :
  
Synonyms : C-FMS|CD115|CSF-1R|CSFR|FIM2|FMS|HDLS|M-CSF-R / colony stimulating factor 1 receptor / CSF1R
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203104_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001275634.1
RefSeq - NP_001336665.1
RefSeq - NP_005202.2
RefSeq - 1168720172
RefSeq - NG_012303.1
RefSeq - 27262659
RefSeq - 569026720
RefSeq - NC_000005.10
RefSeq - NR_109969.1
RefSeq - NM_001288705.2
RefSeq - NM_001349736.1
RefSeq - NM_005211.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000182578 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway ISS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0021772 olfactory bulb development IEA
 biological_processGO:0021879 forebrain neuron differentiation IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030224 monocyte differentiation TAS
 biological_processGO:0030225 macrophage differentiation TAS
 biological_processGO:0030316 osteoclast differentiation ISS
 biological_processGO:0030335 positive regulation of cell migration ISS
 biological_processGO:0031529 ruffle organization ISS
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0036006 cellular response to macrophage colony-stimulating factor stimulus IMP
 biological_processGO:0038145 macrophage colony-stimulating factor signaling pathway ISS
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ISS
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045124 regulation of bone resorption ISS
 biological_processGO:0045217 cell-cell junction maintenance IMP
 biological_processGO:0046488 phosphatidylinositol metabolic process ISS
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling ISS
 biological_processGO:0060603 mammary gland duct morphogenesis TAS
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0071345 cellular response to cytokine stimulus ISS
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity ISS
 biological_processGO:0090197 positive regulation of chemokine secretion IMP
 biological_processGO:2000147 positive regulation of cell motility IMP
 biological_processGO:2000249 regulation of actin cytoskeleton reorganization ISS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface ISS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:1990682 CSF1-CSF1R complex ISS
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005011 macrophage colony-stimulating factor receptor activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0019955 cytokine binding ISS
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042803 protein homodimerization activity ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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