1540


Homo sapiens (NCBI)

Features
Gene ID: 1540
  
Biological name :
  
Synonyms : BRSS|CDMT|CYLD1|CYLDI|EAC|MFT|MFT1|SBS|TEM|USPL2 / CYLD / CYLD lysine 63 deubiquitinase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 213295_at (Human Genome U133 Plus 2.0 Array)   214272_at (Human Genome U133 Plus 2.0 Array)   221903_s_at (Human Genome U133 Plus 2.0 Array)   221905_at (Human Genome U133 Plus 2.0 Array)   222142_at (Human Genome U133 Plus 2.0 Array)   39582_at (Human Genome U133 Plus 2.0 Array)   60084_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767989483
RefSeq - 1034593759
RefSeq - 1034593761
RefSeq - 1034593764
RefSeq - 1034593766
RefSeq - 109637774
RefSeq - 109637776
RefSeq - 14165258
RefSeq - 530423617
RefSeq - 578828864
RefSeq - 1034593757
RefSeq - 767989485
RefSeq - 767989491
RefSeq - NC_000016.10
RefSeq - NG_012061.1
RefSeq - NP_001035814.1
RefSeq - NP_001035877.1
RefSeq - NP_056062.1
RefSeq - XP_005255869.1
RefSeq - XP_006721212.1
RefSeq - XP_011521209.1
RefSeq - XP_011521210.1
RefSeq - XP_011521213.1
RefSeq - XP_016878466.1
RefSeq - XP_016878467.1
RefSeq - XP_016878468.1
RefSeq - XP_016878469.1
RefSeq - XP_016878470.1
RefSeq - XM_017022979.1
RefSeq - XM_017022980.1
RefSeq - NM_001042355.1
RefSeq - NM_001042412.1
RefSeq - NM_015247.2
RefSeq - XM_017022981.2
RefSeq - XR_001751849.1
RefSeq - XR_933218.1
RefSeq - XM_005255812.2
RefSeq - XM_006721149.1
RefSeq - XM_011522907.2
RefSeq - XM_011522908.1
RefSeq - XM_011522911.2
RefSeq - XM_017022977.1
RefSeq - XM_017022978.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000083799 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IMP
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0032480 negative regulation of type I interferon production TAS
 biological_processGO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment IEA
 biological_processGO:0043393 regulation of protein binding IEA
 biological_processGO:0045087 innate immune response IDA
 biological_processGO:0045577 regulation of B cell differentiation IEA
 biological_processGO:0045581 negative regulation of T cell differentiation IEA
 biological_processGO:0045582 positive regulation of T cell differentiation IEA
 biological_processGO:0048872 homeostasis of number of cells IEA
 biological_processGO:0050862 positive regulation of T cell receptor signaling pathway IEA
 biological_processGO:0070266 necroptotic process IBA
 biological_processGO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IMP
 biological_processGO:0070536 protein K63-linked deubiquitination IDA
 biological_processGO:0071108 protein K48-linked deubiquitination IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IMP
 biological_processGO:1901026 ripoptosome assembly involved in necroptotic process IEA
 biological_processGO:1901223 negative regulation of NIK/NF-kappaB signaling IDA
 biological_processGO:1902017 regulation of cilium assembly ISS
 biological_processGO:1903829 positive regulation of cellular protein localization IEA
 biological_processGO:1990108 protein linear deubiquitination IDA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IMP
 biological_processGO:2001242 regulation of intrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005819 spindle IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0030496 midbody IDA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0036064 ciliary basal body ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0097542 ciliary tip ISS
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity TAS
 molecular_functionGO:0061578 Lys63-specific deubiquitinase activity TAS
 molecular_functionGO:0070064 proline-rich region binding IPI
 molecular_functionGO:1990380 Lys48-specific deubiquitinase activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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