16194


Mus musculus (NCBI)

Features
Gene ID: 16194
  
Biological name :
  
Synonyms : CD126|IL-6R|IL-6R-alpha|IL-6RA|Il6r / Il6ra / interleukin 6 receptor, alpha
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422270_a_at (Mouse Genome 430 2.0 Array)   1452416_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - NP_001297605.1
RefSeq - NP_034689.2
RefSeq - NC_000069.6
RefSeq - 110431356
RefSeq - 893567041
RefSeq - NM_001310676.1
RefSeq - NM_010559.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000027947 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002827 positive regulation of T-helper 1 type immune response IBA
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0010536 positive regulation of activation of Janus kinase activity ISO
 biological_processGO:0019221 cytokine-mediated signaling pathway ISO
 biological_processGO:0031018 endocrine pancreas development ISO
 biological_processGO:0032722 positive regulation of chemokine production ISO
 biological_processGO:0032729 positive regulation of interferon-gamma production IBA
 biological_processGO:0032755 positive regulation of interleukin-6 production ISO
 biological_processGO:0032816 positive regulation of natural killer cell activation IBA
 biological_processGO:0032966 negative regulation of collagen biosynthetic process ISO
 biological_processGO:0034097 response to cytokine ISO
 biological_processGO:0042104 positive regulation of activated T cell proliferation IBA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ISO
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0048589 developmental growth ISO
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0050671 positive regulation of lymphocyte proliferation IBA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0051135 positive regulation of NK T cell activation IBA
 biological_processGO:0070102 interleukin-6-mediated signaling pathway ISO
 biological_processGO:0070120 ciliary neurotrophic factor-mediated signaling pathway ISO
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005896 interleukin-6 receptor complex ISO
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISO
 cellular_componentGO:0032809 neuronal cell body membrane ISO
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0043514 interleukin-12 complex IBA
 cellular_componentGO:0070110 ciliary neurotrophic factor receptor complex ISO
 cellular_componentGO:0070743 interleukin-23 complex IBA
 molecular_functionGO:0004896 cytokine receptor activity IEA
 molecular_functionGO:0004897 ciliary neurotrophic factor receptor activity ISO
 molecular_functionGO:0004915 interleukin-6 receptor activity ISO
 molecular_functionGO:0005138 interleukin-6 receptor binding ISO
 molecular_functionGO:0005143 interleukin-12 receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IBA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019955 cytokine binding IBA
 molecular_functionGO:0019981 interleukin-6 binding ISO
 molecular_functionGO:0042164 interleukin-12 alpha subunit binding IBA
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0045519 interleukin-23 receptor binding IBA
 molecular_functionGO:0070119 ciliary neurotrophic factor binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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