16392


Mus musculus (NCBI)

Features
Gene ID: 16392
  
Biological name :
  
Synonyms : Isl1 / ISL1 transcription factor, LIM/homeodomain
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422720_at (Mouse Genome 430 2.0 Array)   1450723_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_017170887.1
RefSeq - 162287065
RefSeq - 568984228
RefSeq - NC_000079.6
RefSeq - NP_067434.3
RefSeq - XP_006517596.1
RefSeq - 1039743193
RefSeq - NM_021459.4
RefSeq - XM_017315398.1
RefSeq - XM_006517533.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000042258 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0001755 neural crest cell migration IGI
 biological_processGO:0003007 heart morphogenesis IGI
 biological_processGO:0003139 secondary heart field specification ISO
 biological_processGO:0003148 outflow tract septum morphogenesis IGI
 biological_processGO:0003151 outflow tract morphogenesis IGI
 biological_processGO:0003203 endocardial cushion morphogenesis IGI
 biological_processGO:0003215 cardiac right ventricle morphogenesis IGI
 biological_processGO:0003266 regulation of secondary heart field cardioblast proliferation IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISO
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production IDA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition ISO
 biological_processGO:0021520 spinal cord motor neuron cell fate specification IGI
 biological_processGO:0021522 spinal cord motor neuron differentiation IMP
 biological_processGO:0021524 visceral motor neuron differentiation IGI
 biological_processGO:0021559 trigeminal nerve development IMP
 biological_processGO:0021983 pituitary gland development IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030182 neuron differentiation IMP
 biological_processGO:0031016 pancreas development IMP
 biological_processGO:0031290 retinal ganglion cell axon guidance IMP
 biological_processGO:0032024 positive regulation of insulin secretion ISO
 biological_processGO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production IDA
 biological_processGO:0032729 positive regulation of interferon-gamma production IDA
 biological_processGO:0032730 positive regulation of interleukin-1 alpha production IDA
 biological_processGO:0032731 positive regulation of interleukin-1 beta production IDA
 biological_processGO:0032735 positive regulation of interleukin-12 production IDA
 biological_processGO:0032755 positive regulation of interleukin-6 production IDA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IDA
 biological_processGO:0033147 negative regulation of intracellular estrogen receptor signaling pathway ISO
 biological_processGO:0035066 positive regulation of histone acetylation IMP
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IDA
 biological_processGO:0043388 positive regulation of DNA binding IDA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:0045597 positive regulation of cell differentiation IMP
 biological_processGO:0045665 negative regulation of neuron differentiation IGI
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0048663 neuron fate commitment IGI
 biological_processGO:0048665 neuron fate specification IMP
 biological_processGO:0048762 mesenchymal cell differentiation IMP
 biological_processGO:0048880 sensory system development IMP
 biological_processGO:0048935 peripheral nervous system neuron development IGI
 biological_processGO:0048936 peripheral nervous system neuron axonogenesis IMP
 biological_processGO:0050680 negative regulation of epithelial cell proliferation ISO
 biological_processGO:0050728 negative regulation of inflammatory response IMP
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IGI
 biological_processGO:0060037 pharyngeal system development IGI
 biological_processGO:0060379 cardiac muscle cell myoblast differentiation IMP
 biological_processGO:0060384 innervation IMP
 biological_processGO:0060413 atrial septum morphogenesis IGI
 biological_processGO:0060913 cardiac cell fate determination ISO
 biological_processGO:0071657 positive regulation of granulocyte colony-stimulating factor production IDA
 biological_processGO:0090074 negative regulation of protein homodimerization activity ISO
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IGI
 biological_processGO:1901258 positive regulation of macrophage colony-stimulating factor production IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding ISO
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding ISO
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003713 transcription coactivator activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016922 nuclear receptor binding ISO
 molecular_functionGO:0030331 estrogen receptor binding ISO
 molecular_functionGO:0043425 bHLH transcription factor binding ISO
 molecular_functionGO:0043565 sequence-specific DNA binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1990841 promoter-specific chromatin binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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