16974


Mus musculus (NCBI)

Features
Gene ID: 16974
  
Biological name :
  
Synonyms : C030016K15Rik|Cd|Gw|ska26|ska|skax26 / low density lipoprotein receptor-related protein 6 / Lrp6
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1428500_at (Mouse Genome 430 2.0 Array)   1451022_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 568940906
RefSeq - XP_006505720.1
RefSeq - NC_000072.6
RefSeq - 148727327
RefSeq - NP_032540.2
RefSeq - NM_008514.4
RefSeq - XM_006505657.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000030201 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001702 gastrulation with mouth forming second IGI
 biological_processGO:0001756 somitogenesis IGI
 biological_processGO:0001843 neural tube closure IMP
 biological_processGO:0001933 negative regulation of protein phosphorylation ISO
 biological_processGO:0001947 heart looping IGI
 biological_processGO:0002009 morphogenesis of an epithelium IMP
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IMP
 biological_processGO:0003344 pericardium morphogenesis IGI
 biological_processGO:0003401 axis elongation IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated ISO
 biological_processGO:0006469 negative regulation of protein kinase activity ISO
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration ISO
 biological_processGO:0007268 chemical synaptic transmission ISO
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009880 embryonic pattern specification IMP
 biological_processGO:0009950 dorsal/ventral axis specification IMP
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0010976 positive regulation of neuron projection development IGI
 biological_processGO:0014029 neural crest formation ISO
 biological_processGO:0014033 neural crest cell differentiation ISO
 biological_processGO:0016055 Wnt signaling pathway ISO
 biological_processGO:0021587 cerebellum morphogenesis IMP
 biological_processGO:0021794 thalamus development IMP
 biological_processGO:0021795 cerebral cortex cell migration IMP
 biological_processGO:0021861 forebrain radial glial cell differentiation IGI
 biological_processGO:0021872 forebrain generation of neurons IMP
 biological_processGO:0021874 Wnt signaling pathway involved in forebrain neuroblast division IMP
 biological_processGO:0021915 neural tube development IGI
 biological_processGO:0021943 formation of radial glial scaffolds IGI
 biological_processGO:0021987 cerebral cortex development IMP
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IGI
 biological_processGO:0030278 regulation of ossification IBA
 biological_processGO:0030326 embryonic limb morphogenesis IGI
 biological_processGO:0030900 forebrain development IMP
 biological_processGO:0030901 midbrain development IMP
 biological_processGO:0030917 midbrain-hindbrain boundary development IMP
 biological_processGO:0034392 negative regulation of smooth muscle cell apoptotic process ISO
 biological_processGO:0035108 limb morphogenesis IMP
 biological_processGO:0035115 embryonic forelimb morphogenesis IMP
 biological_processGO:0035116 embryonic hindlimb morphogenesis IMP
 biological_processGO:0035261 external genitalia morphogenesis IMP
 biological_processGO:0036342 post-anal tail morphogenesis IMP
 biological_processGO:0042074 cell migration involved in gastrulation IGI
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IMP
 biological_processGO:0042733 embryonic digit morphogenesis IMP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification ISO
 biological_processGO:0045599 negative regulation of fat cell differentiation IMP
 biological_processGO:0045778 positive regulation of ossification IMP
 biological_processGO:0045780 positive regulation of bone resorption IMP
 biological_processGO:0045787 positive regulation of cell cycle ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046849 bone remodeling IGI
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IMP
 biological_processGO:0048699 generation of neurons IMP
 biological_processGO:0048705 skeletal system morphogenesis IMP
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IMP
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 biological_processGO:0051593 response to folic acid IMP
 biological_processGO:0060021 roof of mouth development IMP
 biological_processGO:0060026 convergent extension IGI
 biological_processGO:0060042 retina morphogenesis in camera-type eye IMP
 biological_processGO:0060059 embryonic retina morphogenesis in camera-type eye IMP
 biological_processGO:0060070 canonical Wnt signaling pathway ISO
 biological_processGO:0060284 regulation of cell development IMP
 biological_processGO:0060325 face morphogenesis IMP
 biological_processGO:0060349 bone morphogenesis IMP
 biological_processGO:0060444 branching involved in mammary gland duct morphogenesis IMP
 biological_processGO:0060535 trachea cartilage morphogenesis IGI
 biological_processGO:0060596 mammary placode formation IMP
 biological_processGO:0060603 mammary gland duct morphogenesis IGI
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway ISO
 biological_processGO:0061310 canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development IMP
 biological_processGO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation IMP
 biological_processGO:0071397 cellular response to cholesterol ISO
 biological_processGO:0071542 dopaminergic neuron differentiation IMP
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity ISO
 biological_processGO:0072659 protein localization to plasma membrane ISO
 biological_processGO:0090009 primitive streak formation IGI
 biological_processGO:0090118 receptor-mediated endocytosis involved in cholesterol transport IMP
 biological_processGO:0090244 Wnt signaling pathway involved in somitogenesis IMP
 biological_processGO:0090245 axis elongation involved in somitogenesis IGI
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway ISO
 biological_processGO:0098609 cell-cell adhesion ISO
 biological_processGO:2000051 negative regulation of non-canonical Wnt signaling pathway IGI
 biological_processGO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification ISO
 biological_processGO:2000149 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis IGI
 biological_processGO:2000151 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis IGI
 biological_processGO:2000162 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis IGI
 biological_processGO:2000164 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis IGI
 biological_processGO:2000166 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis IGI
 biological_processGO:2000168 negative regulation of planar cell polarity pathway involved in neural tube closure IGI
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005901 caveola ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0045202 synapse ISO
 cellular_componentGO:1990851 Wnt-Frizzled-LRP5/6 complex ISO
 cellular_componentGO:1990909 Wnt signalosome ISO
 molecular_functionGO:0005041 low-density lipoprotein particle receptor activity ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005109 frizzled binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015026 coreceptor activity IBA
 molecular_functionGO:0017147 Wnt-protein binding ISO
 molecular_functionGO:0019210 kinase inhibitor activity ISO
 molecular_functionGO:0019534 toxin transmembrane transporter activity IMP
 molecular_functionGO:0034185 apolipoprotein binding IPI
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0071936 coreceptor activity involved in Wnt signaling pathway ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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