1739


Homo sapiens (NCBI)

Features
Gene ID: 1739
  
Biological name :
  
Synonyms : discs large MAGUK scaffold protein 1 / DLG1 / DLGH1|SAP-97|SAP97|dJ1061C18.1.1|hdlg
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202514_at (Human Genome U133 Plus 2.0 Array)   202515_at (Human Genome U133 Plus 2.0 Array)   202516_s_at (Human Genome U133 Plus 2.0 Array)   215988_s_at (Human Genome U133 Plus 2.0 Array)   217208_s_at (Human Genome U133 Plus 2.0 Array)   229703_at (Human Genome U133 Plus 2.0 Array)   230229_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 324120938
RefSeq - 1034631520
RefSeq - 1034631522
RefSeq - 1034631524
RefSeq - 1034631526
RefSeq - 1034631529
RefSeq - 1034631531
RefSeq - 1034631533
RefSeq - 1034631535
RefSeq - 1034631537
RefSeq - 1034631539
RefSeq - 1034631541
RefSeq - 1034631543
RefSeq - 1034631545
RefSeq - 1034631547
RefSeq - 1034631549
RefSeq - 1034631551
RefSeq - 1034631553
RefSeq - 1034631555
RefSeq - 1034631557
RefSeq - 1034631559
RefSeq - 1034631561
RefSeq - 1034631563
RefSeq - 1034631565
RefSeq - 1034631577
RefSeq - 1394533370
RefSeq - 148539578
RefSeq - 148539628
RefSeq - 324120934
RefSeq - 324120936
RefSeq - 1034631518
RefSeq - 530375780
RefSeq - 597436976
RefSeq - 767925917
RefSeq - 767925919
RefSeq - 767925923
RefSeq - 767925925
RefSeq - 767925934
RefSeq - NC_000003.12
RefSeq - NG_029099.1
RefSeq - NP_001091894.1
RefSeq - NP_001191315.1
RefSeq - NP_001191316.1
RefSeq - NP_001191317.1
RefSeq - NP_001277912.1
RefSeq - NP_001350794.1
RefSeq - NP_004078.2
RefSeq - XP_005269346.1
RefSeq - XP_011510804.1
RefSeq - XP_011510805.1
RefSeq - XP_011510807.1
RefSeq - XP_011510808.1
RefSeq - XP_011510811.1
RefSeq - XP_016861289.1
RefSeq - XP_016861290.1
RefSeq - XP_016861291.1
RefSeq - XP_016861292.1
RefSeq - XP_016861293.1
RefSeq - XP_016861294.1
RefSeq - XP_016861295.1
RefSeq - XP_016861296.1
RefSeq - XP_016861297.1
RefSeq - XP_016861298.1
RefSeq - XP_016861299.1
RefSeq - XP_016861300.1
RefSeq - XP_016861301.1
RefSeq - XP_016861302.1
RefSeq - XP_016861303.1
RefSeq - XP_016861304.1
RefSeq - XP_016861305.1
RefSeq - XP_016861306.1
RefSeq - XP_016861307.1
RefSeq - XP_016861308.1
RefSeq - XP_016861309.1
RefSeq - XP_016861310.1
RefSeq - XP_016861311.1
RefSeq - XP_016861312.1
RefSeq - XP_016861313.1
RefSeq - XM_017005818.2
RefSeq - XM_017005819.1
RefSeq - XM_017005820.2
RefSeq - XM_017005821.2
RefSeq - XM_017005822.2
RefSeq - XM_017005823.2
RefSeq - XM_017005824.2
RefSeq - XR_924108.3
RefSeq - XR_001740036.2
RefSeq - XR_001740037.2
RefSeq - NM_001098424.1
RefSeq - NM_001204386.1
RefSeq - NM_001204387.1
RefSeq - NM_001204388.1
RefSeq - NM_001290983.1
RefSeq - NM_001363865.1
RefSeq - NM_004087.2
RefSeq - XR_001740038.2
RefSeq - XR_001740039.2
RefSeq - XR_001740040.2
RefSeq - XR_001740041.2
RefSeq - XR_001740042.1
RefSeq - XR_001740043.2
RefSeq - XR_001740044.2
RefSeq - XM_005269289.4
RefSeq - XM_011512502.3
RefSeq - XM_011512503.2
RefSeq - XM_011512505.2
RefSeq - XM_011512506.2
RefSeq - XM_011512509.2
RefSeq - XM_017005800.1
RefSeq - XM_017005801.1
RefSeq - XM_017005802.1
RefSeq - XM_017005803.1
RefSeq - XM_017005804.2
RefSeq - XM_017005805.2
RefSeq - XM_017005806.2
RefSeq - XM_017005807.1
RefSeq - XM_017005808.1
RefSeq - XM_017005809.2
RefSeq - XM_017005810.1
RefSeq - XM_017005811.2
RefSeq - XM_017005812.1
RefSeq - XM_017005813.1
RefSeq - XM_017005814.2
RefSeq - XM_017005815.2
RefSeq - XM_017005816.2
RefSeq - XM_017005817.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000075711 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0001771 immunological synapse formation IEA
 biological_processGO:0001935 endothelial cell proliferation IDA
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0002369 T cell cytokine production IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007015 actin filament organization IDA
 biological_processGO:0007093 mitotic cell cycle checkpoint NAS
 biological_processGO:0007163 establishment or maintenance of cell polarity TAS
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0016032 viral process IEA
 biological_processGO:0030432 peristalsis IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0030866 cortical actin cytoskeleton organization IDA
 biological_processGO:0030953 astral microtubule organization IMP
 biological_processGO:0031579 membrane raft organization IEA
 biological_processGO:0031641 regulation of myelination IEA
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034629 cellular protein-containing complex localization IMP
 biological_processGO:0042110 T cell activation IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0042391 regulation of membrane potential IDA
 biological_processGO:0042982 amyloid precursor protein metabolic process IEA
 biological_processGO:0043113 receptor clustering IBA
 biological_processGO:0043268 positive regulation of potassium ion transport IDA
 biological_processGO:0043622 cortical microtubule organization IMP
 biological_processGO:0045197 establishment or maintenance of epithelial cell apical/basal polarity IBA
 biological_processGO:0045930 negative regulation of mitotic cell cycle IMP
 biological_processGO:0046037 GMP metabolic process IEA
 biological_processGO:0046710 GDP metabolic process IEA
 biological_processGO:0048608 reproductive structure development IEA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IEA
 biological_processGO:0048745 smooth muscle tissue development IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0051660 establishment of centrosome localization IMP
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 biological_processGO:0060022 hard palate development IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070830 bicellular tight junction assembly IDA
 biological_processGO:0072659 protein localization to plasma membrane TAS
 biological_processGO:0097120 receptor localization to synapse IBA
 biological_processGO:0098609 cell-cell adhesion IDA
 biological_processGO:0098911 regulation of ventricular cardiac muscle cell action potential ISS
 biological_processGO:1901222 regulation of NIK/NF-kappaB signaling IMP
 biological_processGO:1902305 regulation of sodium ion transmembrane transport TAS
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IDA
 biological_processGO:1903286 regulation of potassium ion import ISS
 biological_processGO:1903753 negative regulation of p38MAPK cascade IMP
 biological_processGO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization ISS
 biological_processGO:1903764 regulation of potassium ion export across plasma membrane ISS
 cellular_componentGO:0001772 immunological synapse TAS
 cellular_componentGO:0005605 basal lamina IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005874 microtubule IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005923 bicellular tight junction IDA
 cellular_componentGO:0008328 ionotropic glutamate receptor complex IBA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0014704 intercalated disc TAS
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane IEA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0031253 cell projection membrane IEA
 cellular_componentGO:0031594 neuromuscular junction IEA
 cellular_componentGO:0033268 node of Ranvier IEA
 cellular_componentGO:0035748 myelin sheath abaxonal region IEA
 cellular_componentGO:0042383 sarcolemma IEA
 cellular_componentGO:0043005 neuron projection IBA
 cellular_componentGO:0043219 lateral loop IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097025 MPP7-DLG1-LIN7 complex IDA
 cellular_componentGO:0098839 postsynaptic density membrane IBA
 molecular_functionGO:0004385 guanylate kinase activity TAS
 molecular_functionGO:0004721 phosphoprotein phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0008092 cytoskeletal protein binding TAS
 molecular_functionGO:0015276 ligand-gated ion channel activity TAS
 molecular_functionGO:0015459 potassium channel regulator activity NAS
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019902 phosphatase binding IPI
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IPI
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0035255 ionotropic glutamate receptor binding IBA
 molecular_functionGO:0044325 ion channel binding IPI
 molecular_functionGO:0045296 cadherin binding HDA
 molecular_functionGO:0097016 L27 domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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