18198


Mus musculus (NCBI)
regulationkinaseproteinactivitybindingmembranejunctionphosphorylationneuromuscularsynapticreceptorcellclusteringplasmadevelopmentgrowthgeneexpressionapoptoticprocesserkskeletalmuscleacetylcholine-gatedchannelintegralcomponenttyrosinetransmembranetranscription

Features
Gene ID: 18198
  
Biological name :
  
Synonyms : Mdk4|Mlk|Nsk1|Nsk2|Nsk3 / muscle, skeletal, receptor tyrosine kinase / Musk
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1450511_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 260267048
RefSeq - 260267309
RefSeq - 568926161
RefSeq - 568926165
RefSeq - 82533041
RefSeq - 82533045
RefSeq - 82533047
RefSeq - 82533049
RefSeq - NC_000070.6
RefSeq - NP_001032204.2
RefSeq - NP_001032205.1
RefSeq - NP_001032206.1
RefSeq - NP_001032207.1
RefSeq - NP_001159468.1
RefSeq - NP_035074.2
RefSeq - XP_006537722.1
RefSeq - XP_006537724.1
RefSeq - NM_001037127.2
RefSeq - NM_001037128.1
RefSeq - NM_001037129.1
RefSeq - NM_001037130.1
RefSeq - NM_001165996.1
RefSeq - NM_010944.2
RefSeq - XM_006537659.2
RefSeq - XM_006537661.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000057280 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processanatomical structure developmentcellular component organizationsystem processcellular component biogenesisregulation of biological qualitydevelopmental growthcell communicationcellular response to stimuluscellular developmental processregulation of molecular functioncell deathmacromolecule localizationcellular localizationresponse to abiotic stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processanatomical structure developmentcellular component organizationsystem processcellular component biogenesisregulation of biological qualitydevelopmental growthcell communicationcellular response to stimuluscellular developmental processregulation of molecular functioncell deathmacromolecule localizationcellular localizationresponse to abiotic stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processanatomical structure developmentcellular component organizationsystem processcellular component biogenesisregulation of biological qualitydevelopmental growthcell communicationcellular response to stimuluscellular developmental processregulation of molecular functioncell deathmacromolecule localizationcellular localizationresponse to abiotic stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processanatomical structure developmentcellular component organizationsystem processcellular component biogenesisregulation of biological qualitydevelopmental growthcell communicationcellular response to stimuluscellular developmental processregulation of molecular functioncell deathmacromolecule localizationcellular localizationresponse to abiotic stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processanatomical structure developmentcellular component organizationsystem processcellular component biogenesisregulation of biological qualitydevelopmental growthcell communicationcellular response to stimuluscellular developmental processregulation of molecular functioncell deathmacromolecule localizationcellular localizationresponse to abiotic stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processanatomical structure developmentcellular component organizationsystem processcellular component biogenesisregulation of biological qualitydevelopmental growthcell communicationcellular response to stimuluscellular developmental processregulation of molecular functioncell deathmacromolecule localizationcellular localizationresponse to abiotic stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processanatomical structure developmentcellular component organizationsystem processcellular component biogenesisregulation of biological qualitydevelopmental growthcell communicationcellular response to stimuluscellular developmental processregulation of molecular functioncell deathmacromolecule localizationcellular localizationresponse to abiotic stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processanatomical structure developmentcellular component organizationsystem processcellular component biogenesisregulation of biological qualitydevelopmental growthcell communicationcellular response to stimuluscellular developmental processregulation of molecular functioncell deathmacromolecule localizationcellular localizationresponse to abiotic stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processanatomical structure developmentcellular component organizationsystem processcellular component biogenesisregulation of biological qualitydevelopmental growthcell communicationcellular response to stimuluscellular developmental processregulation of molecular functioncell deathmacromolecule localizationcellular localizationresponse to abiotic stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processanatomical structure developmentcellular component organizationsystem processcellular component biogenesisregulation of biological qualitydevelopmental growthcell communicationcellular response to stimuluscellular developmental processregulation of molecular functioncell deathmacromolecule localizationcellular localizationresponse to abiotic stimulusnitrogenitrogen compound metabolic processcellulacellular metabolic processprimaryprimary metabolic processorganicorganic substance metabolic processbiosyntbiosynthetic processanatomianatomical structure developmentcellulacellular component organizationsystem system processcellulacellular component biogenesisregulatregulation of biological qualitydevelopdevelopmental growthcell cocell communicationcellulacellular response to stimuluscellulacellular developmental processregulatregulation of molecular functioncell decell deathmacromomacromolecule localizationcellulacellular localizationresponsresponse to abiotic stimulus
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclicorganic cyclic compound bindingheterocyclic cheterocyclic compound bindingsmall moleculesmall molecule bindingcatalytic acticatalytic activity, acting on a proteintransferase actransferase activitysignaling recesignaling receptor activityprotein bindinprotein bindingion bindingion bindingcarbohydrate dcarbohydrate derivative bindingdrug bindingdrug binding
cellmembranecell junctionsynapseprotein-containing complexcellmembranecell junctionsynapseprotein-containing complexcellmembranecell junctionsynapseprotein-containing complexcellmembranecell junctionsynapseprotein-containing complexcellmembranecell junctionsynapseprotein-containing complexcellmembranecell junctionsynapseprotein-containing complexcellmembranecell junctionsynapseprotein-containing complexcellmembranecell junctionsynapseprotein-containing complexcellmembranecell junctionsynapseprotein-containing complexcellmembranecell junctionsynapseprotein-containing complexcellcellmembranemembranecell junctioncell junctionsynapsesynapseprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0006355 regulation of transcription, DNA-templated IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007528 neuromuscular junction development ISO
 biological_processGO:0007613 memory ISO
 biological_processGO:0008582 regulation of synaptic growth at neuromuscular junction IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0032224 positive regulation of synaptic transmission, cholinergic ISO
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043113 receptor clustering ISO
 biological_processGO:0043525 positive regulation of neuron apoptotic process IMP
 biological_processGO:0045887 positive regulation of synaptic growth at neuromuscular junction ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0051602 response to electrical stimulus ISO
 biological_processGO:0060291 long-term synaptic potentiation ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071340 skeletal muscle acetylcholine-gated channel clustering IMP
 biological_processGO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering IMP
 biological_processGO:2000541 positive regulation of protein geranylgeranylation IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031594 neuromuscular junction ISO
 cellular_componentGO:0042995 cell projection ISO
 cellular_componentGO:0043235 receptor complex ISO
 cellular_componentGO:0045202 synapse IDA
 cellular_componentGO:0045211 postsynaptic membrane IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017147 Wnt-protein binding IBA
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0030165 PDZ domain binding IPI
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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