18438


Mus musculus (NCBI)
ionregulationtransportbindingmembranecellactivitycalciumsignalingchannelcationcardiacmuscleresponseatptransmembranereceptorintegralcomponentbloodneuronalpotentialpurinergicnucleotidepathwayendothelialproteinpostsynapticplasmaatp-gated

Features
Gene ID: 18438
  
Biological name :
  
Synonyms : AI504491|AW555605|D5Ertd444e|P2X4 / P2rx4 / purinergic receptor P2X, ligand-gated ion channel 4
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1425525_a_at (Mouse Genome 430 2.0 Array)   1441772_at (Mouse Genome 430 2.0 Array)   1446429_at (Mouse Genome 430 2.0 Array)   1452527_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 117676374
RefSeq - 568936926
RefSeq - 894216119
RefSeq - 894216225
RefSeq - NC_000071.6
RefSeq - NP_001297647.1
RefSeq - NP_001297649.1
RefSeq - NP_035156.2
RefSeq - XP_006530259.1
RefSeq - NM_001310718.1
RefSeq - NM_001310720.1
RefSeq - NM_011026.3
RefSeq - XM_006530196.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000029470 to get all the annotations available for this gene.


Gene Ontology (GO)
establishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processregulation of biological qualitycell communicationcellular response to stimulussystem processcellular localizationmulticellular organismal signalingresponse to external stimulusresponse to chemicalresponse to stresslocalization of cellmovement of cell or subcellular componenttissue migrationcellular component organizationcellular component biogenesisresponse to endogenous stimuluscell deathestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processregulation of biological qualitycell communicationcellular response to stimulussystem processcellular localizationmulticellular organismal signalingresponse to external stimulusresponse to chemicalresponse to stresslocalization of cellmovement of cell or subcellular componenttissue migrationcellular component organizationcellular component biogenesisresponse to endogenous stimuluscell deathestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processregulation of biological qualitycell communicationcellular response to stimulussystem processcellular localizationmulticellular organismal signalingresponse to external stimulusresponse to chemicalresponse to stresslocalization of cellmovement of cell or subcellular componenttissue migrationcellular component organizationcellular component biogenesisresponse to endogenous stimuluscell deathestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processregulation of biological qualitycell communicationcellular response to stimulussystem processcellular localizationmulticellular organismal signalingresponse to external stimulusresponse to chemicalresponse to stresslocalization of cellmovement of cell or subcellular componenttissue migrationcellular component organizationcellular component biogenesisresponse to endogenous stimuluscell deathestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processregulation of biological qualitycell communicationcellular response to stimulussystem processcellular localizationmulticellular organismal signalingresponse to external stimulusresponse to chemicalresponse to stresslocalization of cellmovement of cell or subcellular componenttissue migrationcellular component organizationcellular component biogenesisresponse to endogenous stimuluscell deathestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processregulation of biological qualitycell communicationcellular response to stimulussystem processcellular localizationmulticellular organismal signalingresponse to external stimulusresponse to chemicalresponse to stresslocalization of cellmovement of cell or subcellular componenttissue migrationcellular component organizationcellular component biogenesisresponse to endogenous stimuluscell deathestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processregulation of biological qualitycell communicationcellular response to stimulussystem processcellular localizationmulticellular organismal signalingresponse to external stimulusresponse to chemicalresponse to stresslocalization of cellmovement of cell or subcellular componenttissue migrationcellular component organizationcellular component biogenesisresponse to endogenous stimuluscell deathestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processregulation of biological qualitycell communicationcellular response to stimulussystem processcellular localizationmulticellular organismal signalingresponse to external stimulusresponse to chemicalresponse to stresslocalization of cellmovement of cell or subcellular componenttissue migrationcellular component organizationcellular component biogenesisresponse to endogenous stimuluscell deathestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processregulation of biological qualitycell communicationcellular response to stimulussystem processcellular localizationmulticellular organismal signalingresponse to external stimulusresponse to chemicalresponse to stresslocalization of cellmovement of cell or subcellular componenttissue migrationcellular component organizationcellular component biogenesisresponse to endogenous stimuluscell deathestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processregulation of biological qualitycell communicationcellular response to stimulussystem processcellular localizationmulticellular organismal signalingresponse to external stimulusresponse to chemicalresponse to stresslocalization of cellmovement of cell or subcellular componenttissue migrationcellular component organizationcellular component biogenesisresponse to endogenous stimuluscell deathestabliestablishment of localizationnitrogenitrogen compound metabolic processbiosyntbiosynthetic processcellulacellular metabolic processregulatregulation of biological qualitycell cocell communicationcellulacellular response to stimulussystem system processcellulacellular localizationmulticemulticellular organismal signalingresponsresponse to external stimulusresponsresponse to chemicalresponsresponse to stresslocalizlocalization of cellmovemenmovement of cell or subcellular componenttissue tissue migrationcellulacellular component organizationcellulacellular component biogenesisresponsresponse to endogenous stimuluscell decell death
signaling receptor activitytransmembrane transporter activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingsignaling receptor activitytransmembrane transporter activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingsignaling receptor activitytransmembrane transporter activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingsignaling receptor activitytransmembrane transporter activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingsignaling receptor activitytransmembrane transporter activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingsignaling receptor activitytransmembrane transporter activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingsignaling receptor activitytransmembrane transporter activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingsignaling receptor activitytransmembrane transporter activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingsignaling receptor activitytransmembrane transporter activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingsignaling receptor activitytransmembrane transporter activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingsignaling recepsignaling receptor activitytransmembrane ttransmembrane transporter activityprotein bindingprotein bindingion bindingion bindingcarbohydrate decarbohydrate derivative bindingorganic cyclic organic cyclic compound bindingheterocyclic coheterocyclic compound bindingsmall molecule small molecule bindingdrug bindingdrug binding
cellmembraneorganellesynapsecell junctioncellmembraneorganellesynapsecell junctioncellmembraneorganellesynapsecell junctioncellmembraneorganellesynapsecell junctioncellmembraneorganellesynapsecell junctioncellmembraneorganellesynapsecell junctioncellmembraneorganellesynapsecell junctioncellmembraneorganellesynapsecell junctioncellmembraneorganellesynapsecell junctioncellmembraneorganellesynapsecell junctioncellcellmembranemembraneorganelleorganellesynapsesynapsecell junctioncell junction
TypeGO IDTermEv.Code
 biological_processGO:0002028 regulation of sodium ion transport ISO
 biological_processGO:0006809 nitric oxide biosynthetic process IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IBA
 biological_processGO:0006816 calcium ion transport IMP
 biological_processGO:0007165 signal transduction ISO
 biological_processGO:0008217 regulation of blood pressure ISO
 biological_processGO:0010524 positive regulation of calcium ion transport into cytosol ISO
 biological_processGO:0010614 negative regulation of cardiac muscle hypertrophy ISO
 biological_processGO:0019228 neuronal action potential ISO
 biological_processGO:0019233 sensory perception of pain ISO
 biological_processGO:0033198 response to ATP ISO
 biological_processGO:0034220 ion transmembrane transport ISO
 biological_processGO:0034405 response to fluid shear stress ISO
 biological_processGO:0035590 purinergic nucleotide receptor signaling pathway ISO
 biological_processGO:0042311 vasodilation IMP
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0050850 positive regulation of calcium-mediated signaling ISO
 biological_processGO:0051260 protein homooligomerization ISO
 biological_processGO:0051899 membrane depolarization ISO
 biological_processGO:0055117 regulation of cardiac muscle contraction ISO
 biological_processGO:0055119 relaxation of cardiac muscle ISO
 biological_processGO:0060079 excitatory postsynaptic potential IMP
 biological_processGO:0070588 calcium ion transmembrane transport ISO
 biological_processGO:0071318 cellular response to ATP ISO
 biological_processGO:0097190 apoptotic signaling pathway ISO
 biological_processGO:0098655 cation transmembrane transport IEA
 biological_processGO:2001028 positive regulation of endothelial cell chemotaxis ISO
 cellular_componentGO:0005639 integral component of nuclear inner membrane IBA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0014069 postsynaptic density ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction ISO
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043195 terminal bouton ISO
 cellular_componentGO:0043197 dendritic spine ISO
 cellular_componentGO:0045177 apical part of cell IDA
 cellular_componentGO:0045202 synapse ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0001614 purinergic nucleotide receptor activity ISO
 molecular_functionGO:0004931 extracellularly ATP-gated cation channel activity TAS
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005507 copper ion binding ISO
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0008144 drug binding ISO
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0035381 ATP-gated ion channel activity IBA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0045296 cadherin binding ISO
 molecular_functionGO:0099604 ligand-gated calcium channel activity ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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