1950


Homo sapiens (NCBI)

Features
Gene ID: 1950
  
Biological name :
  
Synonyms : EGF / epidermal growth factor / HOMG4|URG
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206254_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 296011013
RefSeq - 1034638765
RefSeq - 1034638767
RefSeq - 1034638769
RefSeq - 1034638771
RefSeq - 1034638773
RefSeq - 1034638775
RefSeq - 1034638781
RefSeq - 1034638783
RefSeq - 1034638785
RefSeq - 1258116119
RefSeq - 166362728
RefSeq - 1034638763
RefSeq - 296011015
RefSeq - 530377285
RefSeq - 767931306
RefSeq - NC_000004.12
RefSeq - NG_011441.1
RefSeq - NP_001171601.1
RefSeq - NP_001171602.1
RefSeq - NP_001343950.1
RefSeq - NP_001954.2
RefSeq - XP_005262853.1
RefSeq - XP_011530009.1
RefSeq - XP_016863334.1
RefSeq - XP_016863335.1
RefSeq - XP_016863336.1
RefSeq - XP_016863337.1
RefSeq - XP_016863338.1
RefSeq - XP_016863339.1
RefSeq - XP_016863340.1
RefSeq - XP_016863342.1
RefSeq - XP_016863343.1
RefSeq - XP_016863344.1
RefSeq - XM_017007851.1
RefSeq - XM_017007853.1
RefSeq - NM_001178130.2
RefSeq - NM_001178131.2
RefSeq - NM_001357021.1
RefSeq - NM_001963.5
RefSeq - XM_017007854.1
RefSeq - XM_017007855.1
RefSeq - XR_001741156.1
RefSeq - XR_001741157.1
RefSeq - XM_005262796.2
RefSeq - XM_011531707.1
RefSeq - XM_017007845.1
RefSeq - XM_017007846.1
RefSeq - XM_017007847.1
RefSeq - XM_017007848.1
RefSeq - XM_017007849.1
RefSeq - XM_017007850.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000138798 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0001525 angiogenesis IDA
 biological_processGO:0002092 positive regulation of receptor internalization IDA
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007171 activation of transmembrane receptor protein tyrosine kinase activity IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway TAS
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IDA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0021940 positive regulation of cerebellar granule cell precursor proliferation IEA
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0038128 ERBB2 signaling pathway TAS
 biological_processGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway TAS
 biological_processGO:0042327 positive regulation of phosphorylation IDA
 biological_processGO:0043388 positive regulation of DNA binding ISS
 biological_processGO:0043406 positive regulation of MAP kinase activity IDA
 biological_processGO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification IBA
 biological_processGO:0045741 positive regulation of epidermal growth factor-activated receptor activity TAS
 biological_processGO:0045746 negative regulation of Notch signaling pathway TAS
 biological_processGO:0045840 positive regulation of mitotic nuclear division IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0046425 regulation of JAK-STAT cascade ISS
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IEA
 biological_processGO:0051048 negative regulation of secretion IDA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060070 canonical Wnt signaling pathway IBA
 biological_processGO:0060749 mammary gland alveolus development IEA
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0070371 ERK1 and ERK2 cascade IDA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IDA
 biological_processGO:0090279 regulation of calcium ion import IDA
 biological_processGO:0090370 negative regulation of cholesterol efflux IEA
 biological_processGO:1900127 positive regulation of hyaluronan biosynthetic process IDA
 biological_processGO:1901185 negative regulation of ERBB signaling pathway TAS
 biological_processGO:2000008 regulation of protein localization to cell surface IDA
 biological_processGO:2000060 positive regulation of ubiquitin-dependent protein catabolic process IEA
 biological_processGO:2000145 regulation of cell motility TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030665 clathrin-coated vesicle membrane TAS
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0070062 extracellular exosome IDA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005154 epidermal growth factor receptor binding TAS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IDA
 molecular_functionGO:0017147 Wnt-protein binding IBA
 molecular_functionGO:0030297 transmembrane receptor protein tyrosine kinase activator activity TAS
 molecular_functionGO:0042813 Wnt-activated receptor activity IBA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr