1991


Homo sapiens (NCBI)

Features
Gene ID: 1991
  
Biological name :
  
Synonyms : ELA2|GE|HLE|HNE|NE|PMN-E|SCN1 / ELANE / elastase, neutrophil expressed
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206871_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_011526078.1
RefSeq - 768001224
RefSeq - 768001228
RefSeq - NC_000019.10
RefSeq - NG_009627.1
RefSeq - NT_187622.1
RefSeq - XP_011526077.1
RefSeq - 4503549
RefSeq - NP_001963.1
RefSeq - NM_001972.3
RefSeq - XM_011527775.1
RefSeq - XM_011527776.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000197561 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0001878 response to yeast IEA
 biological_processGO:0002438 acute inflammatory response to antigenic stimulus IBA
 biological_processGO:0002523 leukocyte migration involved in inflammatory response IEA
 biological_processGO:0002812 biosynthetic process of antibacterial peptides active against Gram-negative bacteria IDA
 biological_processGO:0006508 proteolysis IDA
 biological_processGO:0006874 cellular calcium ion homeostasis NAS
 biological_processGO:0006909 phagocytosis IBA
 biological_processGO:0009411 response to UV IDA
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0022617 extracellular matrix disassembly TAS
 biological_processGO:0030163 protein catabolic process NAS
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0042742 defense response to bacterium IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043406 positive regulation of MAP kinase activity NAS
 biological_processGO:0044130 negative regulation of growth of symbiont in host IEA
 biological_processGO:0045079 negative regulation of chemokine biosynthetic process IDA
 biological_processGO:0045415 negative regulation of interleukin-8 biosynthetic process IDA
 biological_processGO:0045416 positive regulation of interleukin-8 biosynthetic process IDA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IDA
 biological_processGO:0050728 negative regulation of inflammatory response NAS
 biological_processGO:0050778 positive regulation of immune response IEA
 biological_processGO:0050922 negative regulation of chemotaxis NAS
 biological_processGO:0070945 neutrophil mediated killing of gram-negative bacterium IDA
 biological_processGO:0070947 neutrophil mediated killing of fungus IEA
 biological_processGO:1903238 positive regulation of leukocyte tethering or rolling IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 cellular_componentGO:0030141 secretory granule IDA
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0003714 transcription corepressor activity IMP
 molecular_functionGO:0004175 endopeptidase activity IDA
 molecular_functionGO:0004252 serine-type endopeptidase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding IDA
 molecular_functionGO:0008233 peptidase activity IDA
 molecular_functionGO:0019955 cytokine binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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