20617


Mus musculus (NCBI)

Features
Gene ID: 20617
  
Biological name :
  
Synonyms : NACP|alpha-Syn|alphaSYN / Snca / synuclein, alpha
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1418493_a_at (Mouse Genome 430 2.0 Array)   1431022_at (Mouse Genome 430 2.0 Array)   1436853_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - NP_001035916.1
RefSeq - NP_033247.1
RefSeq - NC_000072.6
RefSeq - 109638747
RefSeq - 6678047
RefSeq - NM_001042451.2
RefSeq - NM_009221.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000025889 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001774 microglial cell activation IMP
 biological_processGO:0001921 positive regulation of receptor recycling ISO
 biological_processGO:0001933 negative regulation of protein phosphorylation ISO
 biological_processGO:0001956 positive regulation of neurotransmitter secretion IDA
 biological_processGO:0001963 synaptic transmission, dopaminergic IMP
 biological_processGO:0006631 fatty acid metabolic process IMP
 biological_processGO:0006638 neutral lipid metabolic process IMP
 biological_processGO:0006644 phospholipid metabolic process IMP
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0007006 mitochondrial membrane organization IMP
 biological_processGO:0007268 chemical synaptic transmission IGI
 biological_processGO:0008344 adult locomotory behavior IGI
 biological_processGO:0010040 response to iron(II) ion ISO
 biological_processGO:0010517 regulation of phospholipase activity ISO
 biological_processGO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway ISO
 biological_processGO:0014048 regulation of glutamate secretion IMP
 biological_processGO:0014059 regulation of dopamine secretion TAS
 biological_processGO:0022898 regulation of transmembrane transporter activity ISO
 biological_processGO:0031115 negative regulation of microtubule polymerization ISO
 biological_processGO:0031623 receptor internalization ISO
 biological_processGO:0031648 protein destabilization ISO
 biological_processGO:0032026 response to magnesium ion ISO
 biological_processGO:0032410 negative regulation of transporter activity ISO
 biological_processGO:0032496 response to lipopolysaccharide ISO
 biological_processGO:0032769 negative regulation of monooxygenase activity ISO
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IMP
 biological_processGO:0034341 response to interferon-gamma ISO
 biological_processGO:0034599 cellular response to oxidative stress IMP
 biological_processGO:0035067 negative regulation of histone acetylation ISO
 biological_processGO:0040012 regulation of locomotion IMP
 biological_processGO:0042416 dopamine biosynthetic process IMP
 biological_processGO:0042417 dopamine metabolic process IGI
 biological_processGO:0042493 response to drug IMP
 biological_processGO:0042775 mitochondrial ATP synthesis coupled electron transport IMP
 biological_processGO:0043030 regulation of macrophage activation IMP
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0043523 regulation of neuron apoptotic process IMP
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0045807 positive regulation of endocytosis ISO
 biological_processGO:0045920 negative regulation of exocytosis ISO
 biological_processGO:0045963 negative regulation of dopamine metabolic process ISO
 biological_processGO:0046928 regulation of neurotransmitter secretion IMP
 biological_processGO:0048148 behavioral response to cocaine ISO
 biological_processGO:0048168 regulation of neuronal synaptic plasticity IMP
 biological_processGO:0048169 regulation of long-term neuronal synaptic plasticity IMP
 biological_processGO:0048488 synaptic vesicle endocytosis IMP
 biological_processGO:0048489 synaptic vesicle transport IMP
 biological_processGO:0050729 positive regulation of inflammatory response ISO
 biological_processGO:0050806 positive regulation of synaptic transmission IMP
 biological_processGO:0050808 synapse organization IGI
 biological_processGO:0050812 regulation of acyl-CoA biosynthetic process IMP
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol ISO
 biological_processGO:0051585 negative regulation of dopamine uptake involved in synaptic transmission ISO
 biological_processGO:0051612 negative regulation of serotonin uptake ISO
 biological_processGO:0051621 regulation of norepinephrine uptake ISO
 biological_processGO:0051622 negative regulation of norepinephrine uptake ISO
 biological_processGO:0055114 oxidation-reduction process ISO
 biological_processGO:0060079 excitatory postsynaptic potential IMP
 biological_processGO:0060291 long-term synaptic potentiation IMP
 biological_processGO:0060732 positive regulation of inositol phosphate biosynthetic process ISO
 biological_processGO:0061024 membrane organization IMP
 biological_processGO:0070495 negative regulation of thrombin-activated receptor signaling pathway ISO
 biological_processGO:0070555 response to interleukin-1 ISO
 biological_processGO:0071280 cellular response to copper ion ISO
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity ISO
 biological_processGO:1901214 regulation of neuron death ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:1901216 positive regulation of neuron death ISO
 biological_processGO:1903284 positive regulation of glutathione peroxidase activity ISO
 biological_processGO:1903285 positive regulation of hydrogen peroxide catabolic process ISO
 biological_processGO:1904715 negative regulation of chaperone-mediated autophagy ISO
 biological_processGO:1905606 regulation of presynapse assembly ISO
 biological_processGO:2000377 regulation of reactive oxygen species metabolic process IMP
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005640 nuclear outer membrane ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane ISO
 cellular_componentGO:0005743 mitochondrial inner membrane ISO
 cellular_componentGO:0005758 mitochondrial intermembrane space ISO
 cellular_componentGO:0005759 mitochondrial matrix ISO
 cellular_componentGO:0005791 rough endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005840 ribosome ISO
 cellular_componentGO:0005856 cytoskeleton IDA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005938 cell cortex ISO
 cellular_componentGO:0008021 synaptic vesicle ISO
 cellular_componentGO:0015629 actin cytoskeleton ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016234 inclusion body ISO
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030426 growth cone ISO
 cellular_componentGO:0030659 cytoplasmic vesicle membrane ISO
 cellular_componentGO:0031092 platelet alpha granule membrane ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043195 terminal bouton ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0043679 axon terminus ISO
 cellular_componentGO:0045202 synapse IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0098793 presynapse ISO
 cellular_componentGO:0099512 supramolecular fiber ISO
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0003779 actin binding ISO
 molecular_functionGO:0005507 copper ion binding ISO
 molecular_functionGO:0005509 calcium ion binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding ISO
 molecular_functionGO:0008017 microtubule binding ISO
 molecular_functionGO:0008198 ferrous iron binding ISO
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0016491 oxidoreductase activity ISO
 molecular_functionGO:0019894 kinesin binding ISO
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0030544 Hsp70 protein binding ISO
 molecular_functionGO:0042393 histone binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0043014 alpha-tubulin binding ISO
 molecular_functionGO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process ISO
 molecular_functionGO:0043274 phospholipase binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047485 protein N-terminus binding ISO
 molecular_functionGO:0048156 tau protein binding ISO
 molecular_functionGO:0048487 beta-tubulin binding ISO
 molecular_functionGO:0050544 arachidonic acid binding IDA
 molecular_functionGO:0051219 phosphoprotein binding ISO
 molecular_functionGO:0070840 dynein complex binding ISO
 molecular_functionGO:1903136 cuprous ion binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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