2066


Homo sapiens (NCBI)

Features
Gene ID: 2066
  
Biological name :
  
Synonyms : ALS19|HER4|p180erbB4 / erb-b2 receptor tyrosine kinase 4 / ERBB4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206794_at (Human Genome U133 Plus 2.0 Array)   214053_at (Human Genome U133 Plus 2.0 Array)   233494_at (Human Genome U133 Plus 2.0 Array)   233498_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034612391
RefSeq - 1034612393
RefSeq - 1034612395
RefSeq - 1034612397
RefSeq - 1034612400
RefSeq - 1034612404
RefSeq - 110825958
RefSeq - 4885215
RefSeq - 530369982
RefSeq - 530369984
RefSeq - 578803911
RefSeq - NC_000002.12
RefSeq - NG_011805.1
RefSeq - NP_001036064.1
RefSeq - NP_005226.1
RefSeq - XP_005246433.1
RefSeq - XP_005246434.1
RefSeq - XP_006712427.1
RefSeq - XP_016859066.1
RefSeq - XP_016859067.1
RefSeq - XP_016859068.1
RefSeq - XP_016859069.1
RefSeq - XP_016859070.1
RefSeq - XP_016859071.1
RefSeq - NM_001042599.1
RefSeq - NM_005235.2
RefSeq - XM_017003581.2
RefSeq - XM_017003582.1
RefSeq - XM_005246376.3
RefSeq - XM_005246377.3
RefSeq - XM_006712364.3
RefSeq - XM_017003577.2
RefSeq - XM_017003578.2
RefSeq - XM_017003579.2
RefSeq - XM_017003580.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000178568 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001755 neural crest cell migration ISS
 biological_processGO:0001934 positive regulation of protein phosphorylation TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IDA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007399 nervous system development ISS
 biological_processGO:0007507 heart development ISS
 biological_processGO:0007595 lactation IMP
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0009880 embryonic pattern specification ISS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0016477 cell migration IDA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0021551 central nervous system morphogenesis ISS
 biological_processGO:0021889 olfactory bulb interneuron differentiation ISS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030334 regulation of cell migration ISS
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IEA
 biological_processGO:0038128 ERBB2 signaling pathway TAS
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IMP
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043653 mitochondrial fragmentation involved in apoptotic process IMP
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0046427 positive regulation of JAK-STAT cascade IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060045 positive regulation of cardiac muscle cell proliferation ISS
 biological_processGO:0060644 mammary gland epithelial cell differentiation ISS
 biological_processGO:0060749 mammary gland alveolus development ISS
 biological_processGO:0061026 cardiac muscle tissue regeneration ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IEA
 biological_processGO:2000010 positive regulation of protein localization to cell surface IEA
 biological_processGO:2000145 regulation of cell motility TAS
 biological_processGO:2001223 negative regulation of neuron migration IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009925 basal plasma membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005154 epidermal growth factor receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IMP
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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