2147


Homo sapiens (NCBI)

Features
Gene ID: 2147
  
Biological name :
  
Synonyms : coagulation factor II, thrombin / F2 / PT|RPRGL2|THPH1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205754_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_000497.1
RefSeq - NP_001298186.1
RefSeq - 4503635
RefSeq - NG_008953.1
RefSeq - 910749465
RefSeq - NC_000011.10
RefSeq - XR_428840.4
RefSeq - NM_000506.4
RefSeq - NM_001311257.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000180210 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006953 acute-phase response IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IDA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0007597 blood coagulation, intrinsic pathway TAS
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0009611 response to wounding IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010544 negative regulation of platelet activation TAS
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030193 regulation of blood coagulation TAS
 biological_processGO:0030194 positive regulation of blood coagulation IDA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0030449 regulation of complement activation TAS
 biological_processGO:0032967 positive regulation of collagen biosynthetic process IDA
 biological_processGO:0042730 fibrinolysis IDA
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0045861 negative regulation of proteolysis IDA
 biological_processGO:0046427 positive regulation of JAK-STAT cascade NAS
 biological_processGO:0048712 negative regulation of astrocyte differentiation IDA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IDA
 biological_processGO:0051480 regulation of cytosolic calcium ion concentration IDA
 biological_processGO:0051838 cytolysis by host of symbiont cells IDA
 biological_processGO:0051918 negative regulation of fibrinolysis TAS
 biological_processGO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide IDA
 biological_processGO:0070945 neutrophil mediated killing of gram-negative bacterium IDA
 biological_processGO:0090218 positive regulation of lipid kinase activity IDA
 biological_processGO:1900016 negative regulation of cytokine production involved in inflammatory response IDA
 biological_processGO:1900182 positive regulation of protein localization to nucleus IDA
 biological_processGO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway IDA
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0072562 blood microparticle HDA
 molecular_functionGO:0001530 lipopolysaccharide binding IDA
 molecular_functionGO:0004252 serine-type endopeptidase activity TAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity TAS
 molecular_functionGO:0008201 heparin binding IDA
 molecular_functionGO:0070053 thrombospondin receptor activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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