21823


Mus musculus (NCBI)
bindingprocessbiosyntheticvesicleactivitysynapticdopaminebehaviorcytoplasmicmembraneironoxygenresponsetyrosineheartdevelopmentaminoacidmorphogenesisneurotransmittereyecellionoxidoreductaseincorporationonehypoxiatransmissiondopaminergicvisual

Features
Gene ID: 21823
  
Biological name :
  
Synonyms : Th / tyrosine hydroxylase
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1420546_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6678337
RefSeq - NC_000073.6
RefSeq - NP_033403.1
RefSeq - NM_009377.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000000214 to get all the annotations available for this gene.


Gene Ontology (GO)
response to stressresponse to abiotic stimuluscell communicationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentsystem processmulticellular organism reproductionlocomotory behaviorestablishment of localizationcellular localizationregulation of biological qualitycellular developmental processfeeding behaviorresponse to chemicaloxidation-reduction processresponse to stressresponse to abiotic stimuluscell communicationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentsystem processmulticellular organism reproductionlocomotory behaviorestablishment of localizationcellular localizationregulation of biological qualitycellular developmental processfeeding behaviorresponse to chemicaloxidation-reduction processresponse to stressresponse to abiotic stimuluscell communicationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentsystem processmulticellular organism reproductionlocomotory behaviorestablishment of localizationcellular localizationregulation of biological qualitycellular developmental processfeeding behaviorresponse to chemicaloxidation-reduction processresponse to stressresponse to abiotic stimuluscell communicationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentsystem processmulticellular organism reproductionlocomotory behaviorestablishment of localizationcellular localizationregulation of biological qualitycellular developmental processfeeding behaviorresponse to chemicaloxidation-reduction processresponse to stressresponse to abiotic stimuluscell communicationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentsystem processmulticellular organism reproductionlocomotory behaviorestablishment of localizationcellular localizationregulation of biological qualitycellular developmental processfeeding behaviorresponse to chemicaloxidation-reduction processresponse to stressresponse to abiotic stimuluscell communicationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentsystem processmulticellular organism reproductionlocomotory behaviorestablishment of localizationcellular localizationregulation of biological qualitycellular developmental processfeeding behaviorresponse to chemicaloxidation-reduction processresponse to stressresponse to abiotic stimuluscell communicationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentsystem processmulticellular organism reproductionlocomotory behaviorestablishment of localizationcellular localizationregulation of biological qualitycellular developmental processfeeding behaviorresponse to chemicaloxidation-reduction processresponse to stressresponse to abiotic stimuluscell communicationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentsystem processmulticellular organism reproductionlocomotory behaviorestablishment of localizationcellular localizationregulation of biological qualitycellular developmental processfeeding behaviorresponse to chemicaloxidation-reduction processresponse to stressresponse to abiotic stimuluscell communicationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentsystem processmulticellular organism reproductionlocomotory behaviorestablishment of localizationcellular localizationregulation of biological qualitycellular developmental processfeeding behaviorresponse to chemicaloxidation-reduction processresponse to stressresponse to abiotic stimuluscell communicationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentsystem processmulticellular organism reproductionlocomotory behaviorestablishment of localizationcellular localizationregulation of biological qualitycellular developmental processfeeding behaviorresponse to chemicaloxidation-reduction processresponsresponse to stressresponsresponse to abiotic stimuluscell cocell communicationnitrogenitrogen compound metabolic processbiosyntbiosynthetic processcellulacellular metabolic processprimaryprimary metabolic processsmall msmall molecule metabolic processorganicorganic substance metabolic processanatomianatomical structure developmentsystem system processmulticemulticellular organism reproductionlocomotlocomotory behaviorestabliestablishment of localizationcellulacellular localizationregulatregulation of biological qualitycellulacellular developmental processfeedingfeeding behaviorresponsresponse to chemicaloxidatioxidation-reduction process
oxidoreductase activityion bindingsmall molecule bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingoxidoreductase activityion bindingsmall molecule bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingoxidoreductase activityion bindingsmall molecule bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingoxidoreductase activityion bindingsmall molecule bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingoxidoreductase activityion bindingsmall molecule bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingoxidoreductase activityion bindingsmall molecule bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingoxidoreductase activityion bindingsmall molecule bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingoxidoreductase activityion bindingsmall molecule bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingoxidoreductase activityion bindingsmall molecule bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingoxidoreductase activityion bindingsmall molecule bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingoxidoreductase acoxidoreductase activityion bindingion bindingsmall molecule bismall molecule bindingdrug bindingdrug bindingprotein bindingprotein bindingorganic cyclic coorganic cyclic compound bindingheterocyclic compheterocyclic compound bindingcofactor bindingcofactor binding
cellorganellesynapsemembranecellorganellesynapsemembranecellorganellesynapsemembranecellorganellesynapsemembranecellorganellesynapsemembranecellorganellesynapsemembranecellorganellesynapsemembranecellorganellesynapsemembranecellorganellesynapsemembranecellorganellesynapsemembranecellcellorganelleorganellesynapsesynapsemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001963 synaptic transmission, dopaminergic IMP
 biological_processGO:0006585 dopamine biosynthetic process from tyrosine TAS
 biological_processGO:0007507 heart development ISO
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0007612 learning IMP
 biological_processGO:0007613 memory IMP
 biological_processGO:0007617 mating behavior IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0008016 regulation of heart contraction IMP
 biological_processGO:0009072 aromatic amino acid family metabolic process IEA
 biological_processGO:0009887 animal organ morphogenesis IMP
 biological_processGO:0015842 aminergic neurotransmitter loading into synaptic vesicle ISO
 biological_processGO:0042136 neurotransmitter biosynthetic process IEA
 biological_processGO:0042416 dopamine biosynthetic process ISO
 biological_processGO:0042418 epinephrine biosynthetic process ISO
 biological_processGO:0042421 norepinephrine biosynthetic process ISO
 biological_processGO:0042423 catecholamine biosynthetic process ISO
 biological_processGO:0042462 eye photoreceptor cell development IMP
 biological_processGO:0042755 eating behavior IMP
 biological_processGO:0045471 response to ethanol ISO
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005790 smooth endoplasmic reticulum ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0008021 synaptic vesicle ISO
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISO
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0030659 cytoplasmic vesicle membrane ISO
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 cellular_componentGO:0033162 melanosome membrane ISO
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043195 terminal bouton ISO
 cellular_componentGO:0043204 perikaryon ISO
 molecular_functionGO:0004497 monooxygenase activity ISO
 molecular_functionGO:0004511 tyrosine 3-monooxygenase activity TAS
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008198 ferrous iron binding ISO
 molecular_functionGO:0008199 ferric iron binding ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016597 amino acid binding ISO
 molecular_functionGO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0019825 oxygen binding ISO
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0034617 tetrahydrobiopterin binding ISO
 molecular_functionGO:0035240 dopamine binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr