21825


Mus musculus (NCBI)

Features
Gene ID: 21825
  
Biological name :
  
Synonyms : Thbs1 / thrombospondin 1 / TSP-1|TSP1|Thbs-1|tbsp1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1421811_at (Mouse Genome 430 2.0 Array)   1450377_at (Mouse Genome 430 2.0 Array)   1460302_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - NP_001300843.1
RefSeq - NP_035710.2
RefSeq - NC_000068.7
RefSeq - 47059073
RefSeq - 927028870
RefSeq - NM_001313914.1
RefSeq - NM_011580.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000040152 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity ISO
 biological_processGO:0001937 negative regulation of endothelial cell proliferation ISO
 biological_processGO:0001953 negative regulation of cell-matrix adhesion ISO
 biological_processGO:0002040 sprouting angiogenesis ISO
 biological_processGO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II ISO
 biological_processGO:0002605 negative regulation of dendritic cell antigen processing and presentation ISO
 biological_processGO:0003151 outflow tract morphogenesis IGI
 biological_processGO:0003197 endocardial cushion development IGI
 biological_processGO:0003417 growth plate cartilage development IMP
 biological_processGO:0006954 inflammatory response ISO
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0007050 cell cycle arrest ISO
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0009612 response to mechanical stimulus ISO
 biological_processGO:0009749 response to glucose ISO
 biological_processGO:0010595 positive regulation of endothelial cell migration ISO
 biological_processGO:0010596 negative regulation of endothelial cell migration ISO
 biological_processGO:0010748 negative regulation of plasma membrane long-chain fatty acid transport ISO
 biological_processGO:0010751 negative regulation of nitric oxide mediated signal transduction ISO
 biological_processGO:0010754 negative regulation of cGMP-mediated signaling ISO
 biological_processGO:0010757 negative regulation of plasminogen activation ISO
 biological_processGO:0010759 positive regulation of macrophage chemotaxis IMP
 biological_processGO:0010763 positive regulation of fibroblast migration ISO
 biological_processGO:0010811 positive regulation of cell-substrate adhesion IDA
 biological_processGO:0016477 cell migration ISO
 biological_processGO:0016525 negative regulation of angiogenesis ISO
 biological_processGO:0018149 peptide cross-linking ISO
 biological_processGO:0030194 positive regulation of blood coagulation ISO
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0032026 response to magnesium ion ISO
 biological_processGO:0032695 negative regulation of interleukin-12 production ISO
 biological_processGO:0034976 response to endoplasmic reticulum stress IMP
 biological_processGO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway ISO
 biological_processGO:0042327 positive regulation of phosphorylation ISO
 biological_processGO:0042535 positive regulation of tumor necrosis factor biosynthetic process ISO
 biological_processGO:0043032 positive regulation of macrophage activation ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0043537 negative regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0043652 engulfment of apoptotic cell ISO
 biological_processGO:0045727 positive regulation of translation ISO
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0048266 behavioral response to pain IMP
 biological_processGO:0048514 blood vessel morphogenesis IGI
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0050921 positive regulation of chemotaxis ISO
 biological_processGO:0051592 response to calcium ion ISO
 biological_processGO:0051897 positive regulation of protein kinase B signaling ISO
 biological_processGO:0051918 negative regulation of fibrinolysis ISO
 biological_processGO:0071636 positive regulation of transforming growth factor beta production ISO
 biological_processGO:0071732 cellular response to nitric oxide IMP
 biological_processGO:0090051 negative regulation of cell migration involved in sprouting angiogenesis ISO
 biological_processGO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors ISO
 biological_processGO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis ISO
 biological_processGO:1903671 negative regulation of sprouting angiogenesis ISO
 biological_processGO:2000353 positive regulation of endothelial cell apoptotic process ISO
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process ISO
 biological_processGO:2001027 negative regulation of endothelial cell chemotaxis ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005577 fibrinogen complex ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016529 sarcoplasmic reticulum IDA
 cellular_componentGO:0030141 secretory granule ISO
 cellular_componentGO:0031012 extracellular matrix ISO
 cellular_componentGO:0031091 platelet alpha granule ISO
 molecular_functionGO:0001786 phosphatidylserine binding ISO
 molecular_functionGO:0001968 fibronectin binding ISO
 molecular_functionGO:0005178 integrin binding ISO
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding ISO
 molecular_functionGO:0017134 fibroblast growth factor binding ISO
 molecular_functionGO:0030169 low-density lipoprotein particle binding ISO
 molecular_functionGO:0043236 laminin binding ISO
 molecular_functionGO:0050431 transforming growth factor beta binding ISO
 molecular_functionGO:0050840 extracellular matrix binding IDA
 molecular_functionGO:0070051 fibrinogen binding ISO
 molecular_functionGO:0070052 collagen V binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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