2237


Homo sapiens (NCBI)

Features
Gene ID: 2237
  
Biological name :
  
Synonyms : FEN1 / FEN-1|MF1|RAD2 / flap structure-specific endonuclease 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204767_s_at (Human Genome U133 Plus 2.0 Array)   204768_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4758356
RefSeq - NC_000011.10
RefSeq - NP_004102.1
RefSeq - NM_004111.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000168496 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination TAS
 biological_processGO:0006260 DNA replication TAS
 biological_processGO:0006281 DNA repair TAS
 biological_processGO:0006302 double-strand break repair TAS
 biological_processGO:0006309 apoptotic DNA fragmentation IBA
 biological_processGO:0007613 memory IEA
 biological_processGO:0009650 UV protection TAS
 biological_processGO:0032201 telomere maintenance via semi-conservative replication TAS
 biological_processGO:0043137 DNA replication, removal of RNA primer IDA
 biological_processGO:0045876 positive regulation of sister chromatid cohesion IMP
 biological_processGO:0060041 retina development in camera-type eye IBA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IDA
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0000287 magnesium ion binding IBA
 molecular_functionGO:0003677 DNA binding IMP
 molecular_functionGO:0003684 damaged DNA binding TAS
 molecular_functionGO:0003690 double-stranded DNA binding TAS
 molecular_functionGO:0004519 endonuclease activity TAS
 molecular_functionGO:0004523 RNA-DNA hybrid ribonuclease activity IDA
 molecular_functionGO:0004527 exonuclease activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008309 double-stranded DNA exodeoxyribonuclease activity TAS
 molecular_functionGO:0008409 5"-3" exonuclease activity IDA
 molecular_functionGO:0017108 5"-flap endonuclease activity TAS
 molecular_functionGO:0030145 manganese ion binding IBA
 molecular_functionGO:0045145 single-stranded DNA 5"-3" exodeoxyribonuclease activity IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048256 flap endonuclease activity IDA
 molecular_functionGO:0051908 double-stranded DNA 5"-3" exodeoxyribonuclease activity IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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