2261


Homo sapiens (NCBI)

Features
Gene ID: 2261
  
Biological name :
  
Synonyms : ACH|CD333|CEK2|HSFGFR3EX|JTK4 / FGFR3 / fibroblast growth factor receptor 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204379_s_at (Human Genome U133 Plus 2.0 Array)   204380_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_011511724.1
RefSeq - 1237937822
RefSeq - 13112048
RefSeq - 254028242
RefSeq - 4503711
RefSeq - 578808120
RefSeq - 578808122
RefSeq - 578808124
RefSeq - 578808126
RefSeq - 578808130
RefSeq - 767929030
RefSeq - 767929032
RefSeq - NC_000004.12
RefSeq - NG_012632.1
RefSeq - NP_000133.1
RefSeq - NP_001156685.1
RefSeq - NP_001341738.1
RefSeq - NP_001341739.1
RefSeq - NP_075254.1
RefSeq - XP_006713931.1
RefSeq - XP_006713932.1
RefSeq - XP_006713933.1
RefSeq - XP_006713934.1
RefSeq - XP_006713936.1
RefSeq - XP_011511722.1
RefSeq - 1236498658
RefSeq - XM_006713869.1
RefSeq - NM_000142.4
RefSeq - NM_001163213.1
RefSeq - NM_001354809.1
RefSeq - NM_001354810.1
RefSeq - NM_022965.3
RefSeq - XM_006713870.1
RefSeq - XM_006713871.1
RefSeq - XM_006713873.1
RefSeq - XM_011513420.1
RefSeq - XM_011513422.1
RefSeq - NR_148971.1
RefSeq - XM_006713868.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000068078 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0001958 endochondral ossification TAS
 biological_processGO:0002062 chondrocyte differentiation TAS
 biological_processGO:0003416 endochondral bone growth TAS
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway TAS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010518 positive regulation of phospholipase activity IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030282 bone mineralization ISS
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035988 chondrocyte proliferation TAS
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IMP
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity TAS
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048640 negative regulation of developmental growth ISS
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060349 bone morphogenesis TAS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070977 bone maturation ISS
 biological_processGO:1902178 fibroblast growth factor receptor apoptotic signaling pathway IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005925 focal adhesion TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0030133 transport vesicle IDA
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005007 fibroblast growth factor-activated receptor activity IMP
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0017134 fibroblast growth factor binding IDA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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