2324


Homo sapiens (NCBI)

Features
Gene ID: 2324
  
Biological name :
  
Synonyms : FLT4 / FLT-4|FLT41|LMPH1A|PCL|VEGFR-3|VEGFR3 / fms related tyrosine kinase 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 210316_at (Human Genome U133 Plus 2.0 Array)   229902_at (Human Genome U133 Plus 2.0 Array)   234379_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034644328
RefSeq - 1034644330
RefSeq - 1034644332
RefSeq - 1034644334
RefSeq - 1034644336
RefSeq - 1034644338
RefSeq - 103472027
RefSeq - 104294888
RefSeq - 1238789368
RefSeq - 767938191
RefSeq - 767938204
RefSeq - NC_000005.10
RefSeq - NG_011536.1
RefSeq - NP_001341918.1
RefSeq - NP_002011.2
RefSeq - NP_891555.2
RefSeq - XP_011532780.1
RefSeq - XP_011532786.1
RefSeq - XP_016864752.1
RefSeq - XP_016864753.1
RefSeq - XP_016864754.1
RefSeq - XP_016864755.1
RefSeq - XP_016864756.1
RefSeq - XP_016864757.1
RefSeq - XM_017009266.1
RefSeq - NM_001354989.1
RefSeq - NM_002020.4
RefSeq - NM_182925.4
RefSeq - XM_017009267.2
RefSeq - XM_017009268.1
RefSeq - XR_001742050.2
RefSeq - XM_011534478.3
RefSeq - XM_011534484.2
RefSeq - XM_017009263.1
RefSeq - XM_017009264.2
RefSeq - XM_017009265.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000037280 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IBA
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IMP
 biological_processGO:0001944 vasculature development ISS
 biological_processGO:0001945 lymph vessel development ISS
 biological_processGO:0001946 lymphangiogenesis ISS
 biological_processGO:0002040 sprouting angiogenesis ISS
 biological_processGO:0003016 respiratory system process IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production IMP
 biological_processGO:0010595 positive regulation of endothelial cell migration IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus IMP
 biological_processGO:0038084 vascular endothelial growth factor signaling pathway IDA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0046330 positive regulation of JNK cascade IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048286 lung alveolus development IEA
 biological_processGO:0048514 blood vessel morphogenesis ISS
 biological_processGO:0060312 regulation of blood vessel remodeling ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0090037 positive regulation of protein kinase C signaling IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IMP
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019838 growth factor binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0036328 VEGF-C-activated receptor activity IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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