23586


Homo sapiens (NCBI)

Features
Gene ID: 23586
  
Biological name :
  
Synonyms : DDX58 / DExD/H-box helicase 58 / RIG-I|RIGI|RLR-1|SGMRT2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 218943_s_at (Human Genome U133 Plus 2.0 Array)   222793_at (Human Genome U133 Plus 2.0 Array)   242961_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 27881482
RefSeq - NC_000009.12
RefSeq - NG_046918.1
RefSeq - NP_055129.2
RefSeq - NM_014314.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000107201 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002230 positive regulation of defense response to virus by host IMP
 biological_processGO:0009597 detection of virus IDA
 biological_processGO:0009615 response to virus TAS
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0030334 regulation of cell migration IDA
 biological_processGO:0032480 negative regulation of type I interferon production TAS
 biological_processGO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production IDA
 biological_processGO:0032727 positive regulation of interferon-alpha production IMP
 biological_processGO:0032728 positive regulation of interferon-beta production IMP
 biological_processGO:0032755 positive regulation of interleukin-6 production IDA
 biological_processGO:0032757 positive regulation of interleukin-8 production IDA
 biological_processGO:0034344 regulation of type III interferon production TAS
 biological_processGO:0035549 positive regulation of interferon-beta secretion IMP
 biological_processGO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus TAS
 biological_processGO:0039529 RIG-I signaling pathway IMP
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0060760 positive regulation of response to cytokine stimulus IMP
 biological_processGO:0071360 cellular response to exogenous dsRNA IMP
 biological_processGO:1902741 positive regulation of interferon-alpha secretion IMP
 biological_processGO:1904469 positive regulation of tumor necrosis factor secretion IMP
 biological_processGO:2000778 positive regulation of interleukin-6 secretion IMP
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005923 bicellular tight junction IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0032587 ruffle membrane IDA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding TAS
 molecular_functionGO:0003727 single-stranded RNA binding IMP
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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