23621


Homo sapiens (NCBI)

Features
Gene ID: 23621
  
Biological name :
  
Synonyms : ASP2|BACE|HSPC104 / BACE1 / beta-secretase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 217904_s_at (Human Genome U133 Plus 2.0 Array)   222462_s_at (Human Genome U133 Plus 2.0 Array)   222463_s_at (Human Genome U133 Plus 2.0 Array)   224335_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 21040364
RefSeq - 21040366
RefSeq - 21040368
RefSeq - 333440466
RefSeq - 333755186
RefSeq - 6912266
RefSeq - NC_000011.10
RefSeq - NG_029372.1
RefSeq - NP_001193977.1
RefSeq - NP_001193978.1
RefSeq - NP_036236.1
RefSeq - NP_620427.1
RefSeq - NP_620428.1
RefSeq - NP_620429.1
RefSeq - NM_001207048.1
RefSeq - NM_001207049.1
RefSeq - NM_012104.4
RefSeq - NM_138971.3
RefSeq - NM_138972.3
RefSeq - NM_138973.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000186318 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IDA
 biological_processGO:0006509 membrane protein ectodomain proteolysis TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0050435 amyloid-beta metabolic process IDA
 biological_processGO:0050804 modulation of chemical synaptic transmission IEA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005771 multivesicular body IDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0070931 Golgi-associated vesicle lumen TAS
 molecular_functionGO:0001540 amyloid-beta binding IPI
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IDA
 molecular_functionGO:0008798 beta-aspartyl-peptidase activity TAS
 molecular_functionGO:0019899 enzyme binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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