2475


Homo sapiens (NCBI)

Features
Gene ID: 2475
  
Biological name :
  
Synonyms : FRAP|FRAP1|FRAP2|RAFT1|RAPT1|SKS / mechanistic target of rapamycin kinase / MTOR
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202288_at (Human Genome U133 Plus 2.0 Array)   215381_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NC_000001.11
RefSeq - XP_005263495.1
RefSeq - XP_011539468.1
RefSeq - XP_016856389.1
RefSeq - XP_016856390.1
RefSeq - XP_016856391.1
RefSeq - XP_024301955.1
RefSeq - 1034557343
RefSeq - NG_033239.1
RefSeq - 1034557345
RefSeq - NP_004949.1
RefSeq - 1034557348
RefSeq - 1370452692
RefSeq - 4826730
RefSeq - 530360517
RefSeq - 767903554
RefSeq - XR_001737087.1
RefSeq - NM_004958.3
RefSeq - XM_005263438.2
RefSeq - XM_011541166.2
RefSeq - XM_017000900.1
RefSeq - XM_017000901.1
RefSeq - XM_017000902.1
RefSeq - XM_024446187.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000198793 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IDA
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0003179 heart valve morphogenesis IEA
 biological_processGO:0005979 regulation of glycogen biosynthetic process IEA
 biological_processGO:0006112 energy reserve metabolic process IEA
 biological_processGO:0006207 "de novo" pyrimidine nucleobase biosynthetic process IEA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0006468 protein phosphorylation IMP
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0007281 germ cell development IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007569 cell aging IEA
 biological_processGO:0007584 response to nutrient IMP
 biological_processGO:0007616 long-term memory IEA
 biological_processGO:0008361 regulation of cell size IMP
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0009267 cellular response to starvation IDA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010507 negative regulation of autophagy ISS
 biological_processGO:0010592 positive regulation of lamellipodium assembly IEA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0010831 positive regulation of myotube differentiation IEA
 biological_processGO:0014042 positive regulation of neuron maturation IEA
 biological_processGO:0014736 negative regulation of muscle atrophy IEA
 biological_processGO:0014823 response to activity IEA
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0016242 negative regulation of macroautophagy IDA
 biological_processGO:0016310 phosphorylation IDA
 biological_processGO:0018105 peptidyl-serine phosphorylation IMP
 biological_processGO:0018107 peptidyl-threonine phosphorylation IEA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0030163 protein catabolic process TAS
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0031529 ruffle organization IEA
 biological_processGO:0031641 regulation of myelination IEA
 biological_processGO:0031669 cellular response to nutrient levels ISS
 biological_processGO:0031929 TOR signaling NAS
 biological_processGO:0031998 regulation of fatty acid beta-oxidation IEA
 biological_processGO:0032095 regulation of response to food IEA
 biological_processGO:0032148 activation of protein kinase B activity TAS
 biological_processGO:0032516 positive regulation of phosphoprotein phosphatase activity TAS
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IMP
 biological_processGO:0034198 cellular response to amino acid starvation IDA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0038202 TORC1 signaling IMP
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043200 response to amino acid IDA
 biological_processGO:0043276 anoikis NAS
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0043610 regulation of carbohydrate utilization IEA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0045670 regulation of osteoclast differentiation ISS
 biological_processGO:0045727 positive regulation of translation IDA
 biological_processGO:0045792 negative regulation of cell size IEA
 biological_processGO:0045945 positive regulation of transcription by RNA polymerase III IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046889 positive regulation of lipid biosynthetic process IMP
 biological_processGO:0048255 mRNA stabilization IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0048714 positive regulation of oligodendrocyte differentiation IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0050882 voluntary musculoskeletal movement IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0051549 positive regulation of keratinocyte migration IMP
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:0055013 cardiac muscle cell development IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 biological_processGO:0060135 maternal process involved in female pregnancy IEA
 biological_processGO:0060252 positive regulation of glial cell proliferation IEA
 biological_processGO:0060999 positive regulation of dendritic spine development IEA
 biological_processGO:0061051 positive regulation of cell growth involved in cardiac muscle cell development IEA
 biological_processGO:0070885 negative regulation of calcineurin-NFAT signaling cascade IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IDA
 biological_processGO:0071233 cellular response to leucine IDA
 biological_processGO:0071456 cellular response to hypoxia ISS
 biological_processGO:0090335 regulation of brown fat cell differentiation IEA
 biological_processGO:0090559 regulation of membrane permeability IEA
 biological_processGO:1900034 regulation of cellular response to heat TAS
 biological_processGO:1901216 positive regulation of neuron death IEA
 biological_processGO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I IMP
 biological_processGO:1903691 positive regulation of wound healing, spreading of epidermal cells IMP
 biological_processGO:1904000 positive regulation of eating behavior IEA
 biological_processGO:1904056 positive regulation of cholangiocyte proliferation IEA
 biological_processGO:1904058 positive regulation of sensory perception of pain IEA
 biological_processGO:1904193 negative regulation of cholangiocyte apoptotic process IEA
 biological_processGO:1904197 positive regulation of granulosa cell proliferation IEA
 biological_processGO:1904206 positive regulation of skeletal muscle hypertrophy IEA
 biological_processGO:1904213 negative regulation of iodide transmembrane transport IEA
 biological_processGO:1904690 positive regulation of cytoplasmic translational initiation TAS
 biological_processGO:1990253 cellular response to leucine starvation IDA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005764 lysosome IMP
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0012505 endomembrane system IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016605 PML body ISS
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031931 TORC1 complex IMP
 cellular_componentGO:0031932 TORC2 complex IDA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0001030 RNA polymerase III type 1 promoter DNA binding IDA
 molecular_functionGO:0001031 RNA polymerase III type 2 promoter DNA binding IDA
 molecular_functionGO:0001032 RNA polymerase III type 3 promoter DNA binding IDA
 molecular_functionGO:0001156 TFIIIC-class transcription factor binding IDA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity TAS
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043022 ribosome binding IEA
 molecular_functionGO:0051219 phosphoprotein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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