25793


Homo sapiens (NCBI)
proteinregulationmitochondrionubiquitinlewybindingactivityligasecomplexbodyautophagyneuronkinasepolyubiquitinationubiquitin-dependentcatabolicprocesstargetingprojectiondevelopmentubiquitinationstabilitylocomotionpost-translationalmodificationlymphocytedifferentiationcyclin-dependentserinethreonine

Features
Gene ID: 25793
  
Biological name :
  
Synonyms : F-box protein 7 / FBX|FBX07|FBX7|PARK15|PKPS / FBXO7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1554423_a_at (Human Genome U133 Plus 2.0 Array)   201178_at (Human Genome U133 Plus 2.0 Array)   243649_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1370482157
RefSeq - 384229053
RefSeq - 74229027
RefSeq - 74229029
RefSeq - 768024487
RefSeq - NC_000022.11
RefSeq - NG_016001.1
RefSeq - NP_001028196.1
RefSeq - NP_001244919.1
RefSeq - NP_036311.3
RefSeq - XP_011528408.1
RefSeq - XP_024307975.1
RefSeq - NM_001033024.1
RefSeq - NM_001257990.1
RefSeq - NM_012179.3
RefSeq - XM_024452207.1
RefSeq - XM_011530106.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000100225 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular component organizationprocess utilizing autophagic mechanismmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processregulation of biological qualitycell activationregulation of molecular functioncell cycleresponse to stressresponse to chemicalcellular response to stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular component organizationprocess utilizing autophagic mechanismmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processregulation of biological qualitycell activationregulation of molecular functioncell cycleresponse to stressresponse to chemicalcellular response to stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular component organizationprocess utilizing autophagic mechanismmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processregulation of biological qualitycell activationregulation of molecular functioncell cycleresponse to stressresponse to chemicalcellular response to stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular component organizationprocess utilizing autophagic mechanismmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processregulation of biological qualitycell activationregulation of molecular functioncell cycleresponse to stressresponse to chemicalcellular response to stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular component organizationprocess utilizing autophagic mechanismmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processregulation of biological qualitycell activationregulation of molecular functioncell cycleresponse to stressresponse to chemicalcellular response to stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular component organizationprocess utilizing autophagic mechanismmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processregulation of biological qualitycell activationregulation of molecular functioncell cycleresponse to stressresponse to chemicalcellular response to stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular component organizationprocess utilizing autophagic mechanismmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processregulation of biological qualitycell activationregulation of molecular functioncell cycleresponse to stressresponse to chemicalcellular response to stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular component organizationprocess utilizing autophagic mechanismmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processregulation of biological qualitycell activationregulation of molecular functioncell cycleresponse to stressresponse to chemicalcellular response to stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular component organizationprocess utilizing autophagic mechanismmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processregulation of biological qualitycell activationregulation of molecular functioncell cycleresponse to stressresponse to chemicalcellular response to stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processcellular component organizationprocess utilizing autophagic mechanismmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processregulation of biological qualitycell activationregulation of molecular functioncell cycleresponse to stressresponse to chemicalcellular response to stimuluscell deathnitrogenitrogen compound metabolic processcellulacellular metabolic processprimaryprimary metabolic processorganicorganic substance metabolic processcatabolcatabolic processcellulacellular component organizationprocessprocess utilizing autophagic mechanismmacromomacromolecule localizationestabliestablishment of localizationcellulacellular localizationanatomianatomical structure developmentcellulacellular developmental processregulatregulation of biological qualitycell accell activationregulatregulation of molecular functioncell cycell cycleresponsresponse to stressresponsresponse to chemicalcellulacellular response to stimuluscell decell death
catalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteincatalytic activity, acting on a proteintransferase activitytransferase activityprotein bindingprotein binding
cellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellcellprotein-containing complexprotein-containing complexorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0000422 autophagy of mitochondrion IMP
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0006626 protein targeting to mitochondrion IMP
 biological_processGO:0010975 regulation of neuron projection development IMP
 biological_processGO:0016567 protein ubiquitination IMP
 biological_processGO:0031647 regulation of protein stability IDA
 biological_processGO:0040012 regulation of locomotion IDA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0045620 negative regulation of lymphocyte differentiation IEA
 biological_processGO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity IEA
 biological_processGO:1903204 negative regulation of oxidative stress-induced neuron death IMP
 biological_processGO:1903599 positive regulation of autophagy of mitochondrion IDA
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0097409 glial cytoplasmic inclusion IDA
 cellular_componentGO:0097414 classical Lewy body IDA
 cellular_componentGO:0097462 Lewy neurite IDA
 cellular_componentGO:1990037 Lewy body core IDA
 cellular_componentGO:1990038 Lewy body corona IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0043130 ubiquitin binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr