26191


Homo sapiens (NCBI)

Features
Gene ID: 26191
  
Biological name :
  
Synonyms : LYP|LYP1|LYP2|PEP|PTPN22.5|PTPN22.6|PTPN8 / protein tyrosine phosphatase, non-receptor type 22 / PTPN22
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206060_s_at (Human Genome U133 Plus 2.0 Array)   208010_s_at (Human Genome U133 Plus 2.0 Array)   208011_at (Human Genome U133 Plus 2.0 Array)   236539_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016856495.1
RefSeq - 1034557659
RefSeq - 1034557661
RefSeq - 224586929
RefSeq - 301171662
RefSeq - 301171669
RefSeq - 767903700
RefSeq - 767903702
RefSeq - 767903704
RefSeq - 767903708
RefSeq - 815891380
RefSeq - NC_000001.11
RefSeq - NG_011432.1
RefSeq - NP_001180360.1
RefSeq - NP_001295226.1
RefSeq - NP_036543.4
RefSeq - NP_057051.3
RefSeq - XP_011539523.1
RefSeq - XP_011539524.1
RefSeq - XP_011539525.1
RefSeq - XP_011539527.1
RefSeq - XP_016856493.1
RefSeq - XP_016856494.1
RefSeq - 1034557656
RefSeq - NM_001193431.2
RefSeq - NM_001308297.1
RefSeq - NM_012411.5
RefSeq - NM_015967.6
RefSeq - XM_011541225.2
RefSeq - XM_017001004.1
RefSeq - XM_017001005.2
RefSeq - XM_017001006.1
RefSeq - XM_011541221.1
RefSeq - XM_011541222.1
RefSeq - XM_011541223.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000134242 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation TAS
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0010507 negative regulation of autophagy IMP
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0030217 T cell differentiation ISS
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IMP
 biological_processGO:0032481 positive regulation of type I interferon production IMP
 biological_processGO:0032496 response to lipopolysaccharide IMP
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IMP
 biological_processGO:0032817 regulation of natural killer cell proliferation IDA
 biological_processGO:0034141 positive regulation of toll-like receptor 3 signaling pathway IMP
 biological_processGO:0034145 positive regulation of toll-like receptor 4 signaling pathway IMP
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0035644 phosphoanandamide dephosphorylation ISS
 biological_processGO:0043508 negative regulation of JUN kinase activity IMP
 biological_processGO:0045088 regulation of innate immune response IC
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0050855 regulation of B cell receptor signaling pathway NAS
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway IDA
 biological_processGO:0050868 negative regulation of T cell activation IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway IMP
 biological_processGO:0071225 cellular response to muramyl dipeptide IDA
 biological_processGO:1900165 negative regulation of interleukin-6 secretion IMP
 biological_processGO:1901222 regulation of NIK/NF-kappaB signaling IMP
 biological_processGO:1902523 positive regulation of protein K63-linked ubiquitination IMP
 biological_processGO:1902715 positive regulation of interferon-gamma secretion IMP
 biological_processGO:1903753 negative regulation of p38MAPK cascade IMP
 biological_processGO:2000483 negative regulation of interleukin-8 secretion IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016791 phosphatase activity IDA
 molecular_functionGO:0017124 SH3 domain binding ISS
 molecular_functionGO:0019900 kinase binding ISS
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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