2625


Homo sapiens (NCBI)
regulationcelldevelopmentbindingtranscriptionresponsednadifferentiationrnapolymeraseiisignalingfactormorphogenesisinterleukin-sequence-specificactivityformationpathwaycellularsecretioninvolvedproteinproductionprocesstreceptorhistoneh-k

Features
Gene ID: 2625
  
Biological name :
  
Synonyms : GATA3 / GATA binding protein 3 / HDR|HDRS
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209602_s_at (Human Genome U133 Plus 2.0 Array)   209603_at (Human Genome U133 Plus 2.0 Array)   209604_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4503929
RefSeq - 50541959
RefSeq - 530392139
RefSeq - 530392141
RefSeq - NC_000010.11
RefSeq - NG_015859.1
RefSeq - NP_001002295.1
RefSeq - NP_002042.1
RefSeq - XP_005252499.1
RefSeq - XP_005252500.1
RefSeq - NM_001002295.1
RefSeq - NM_002051.2
RefSeq - XM_005252442.2
RefSeq - XM_005252443.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000107485 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentresponse to stressimmune responseimmune effector processcell activationcellular component organizationcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicalregulation of biological qualitycoagulationresponse to biotic stimulusresponse to abiotic stimulustissue migrationcytokine productionepithelial cell proliferationdevelopmental maturationestablishment of localizationsystem processcell deathresponse to estrogencell adhesioncell cycledevelopmental growthmethylationresponse to endogenous stimulusmacromolecule localizationdemethylationestablishment or maintenance of cell polarityproduction of molecular mediator of immune responseregulation of molecular functionnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentresponse to stressimmune responseimmune effector processcell activationcellular component organizationcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicalregulation of biological qualitycoagulationresponse to biotic stimulusresponse to abiotic stimulustissue migrationcytokine productionepithelial cell proliferationdevelopmental maturationestablishment of localizationsystem processcell deathresponse to estrogencell adhesioncell cycledevelopmental growthmethylationresponse to endogenous stimulusmacromolecule localizationdemethylationestablishment or maintenance of cell polarityproduction of molecular mediator of immune responseregulation of molecular functionnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentresponse to stressimmune responseimmune effector processcell activationcellular component organizationcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicalregulation of biological qualitycoagulationresponse to biotic stimulusresponse to abiotic stimulustissue migrationcytokine productionepithelial cell proliferationdevelopmental maturationestablishment of localizationsystem processcell deathresponse to estrogencell adhesioncell cycledevelopmental growthmethylationresponse to endogenous stimulusmacromolecule localizationdemethylationestablishment or maintenance of cell polarityproduction of molecular mediator of immune responseregulation of molecular functionnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentresponse to stressimmune responseimmune effector processcell activationcellular component organizationcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicalregulation of biological qualitycoagulationresponse to biotic stimulusresponse to abiotic stimulustissue migrationcytokine productionepithelial cell proliferationdevelopmental maturationestablishment of localizationsystem processcell deathresponse to estrogencell adhesioncell cycledevelopmental growthmethylationresponse to endogenous stimulusmacromolecule localizationdemethylationestablishment or maintenance of cell polarityproduction of molecular mediator of immune responseregulation of molecular functionnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentresponse to stressimmune responseimmune effector processcell activationcellular component organizationcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicalregulation of biological qualitycoagulationresponse to biotic stimulusresponse to abiotic stimulustissue migrationcytokine productionepithelial cell proliferationdevelopmental maturationestablishment of localizationsystem processcell deathresponse to estrogencell adhesioncell cycledevelopmental growthmethylationresponse to endogenous stimulusmacromolecule localizationdemethylationestablishment or maintenance of cell polarityproduction of molecular mediator of immune responseregulation of molecular functionnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentresponse to stressimmune responseimmune effector processcell activationcellular component organizationcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicalregulation of biological qualitycoagulationresponse to biotic stimulusresponse to abiotic stimulustissue migrationcytokine productionepithelial cell proliferationdevelopmental maturationestablishment of localizationsystem processcell deathresponse to estrogencell adhesioncell cycledevelopmental growthmethylationresponse to endogenous stimulusmacromolecule localizationdemethylationestablishment or maintenance of cell polarityproduction of molecular mediator of immune responseregulation of molecular functionnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentresponse to stressimmune responseimmune effector processcell activationcellular component organizationcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicalregulation of biological qualitycoagulationresponse to biotic stimulusresponse to abiotic stimulustissue migrationcytokine productionepithelial cell proliferationdevelopmental maturationestablishment of localizationsystem processcell deathresponse to estrogencell adhesioncell cycledevelopmental growthmethylationresponse to endogenous stimulusmacromolecule localizationdemethylationestablishment or maintenance of cell polarityproduction of molecular mediator of immune responseregulation of molecular functionnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentresponse to stressimmune responseimmune effector processcell activationcellular component organizationcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicalregulation of biological qualitycoagulationresponse to biotic stimulusresponse to abiotic stimulustissue migrationcytokine productionepithelial cell proliferationdevelopmental maturationestablishment of localizationsystem processcell deathresponse to estrogencell adhesioncell cycledevelopmental growthmethylationresponse to endogenous stimulusmacromolecule localizationdemethylationestablishment or maintenance of cell polarityproduction of molecular mediator of immune responseregulation of molecular functionnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentresponse to stressimmune responseimmune effector processcell activationcellular component organizationcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicalregulation of biological qualitycoagulationresponse to biotic stimulusresponse to abiotic stimulustissue migrationcytokine productionepithelial cell proliferationdevelopmental maturationestablishment of localizationsystem processcell deathresponse to estrogencell adhesioncell cycledevelopmental growthmethylationresponse to endogenous stimulusmacromolecule localizationdemethylationestablishment or maintenance of cell polarityproduction of molecular mediator of immune responseregulation of molecular functionnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processlocalization of cellmovement of cell or subcellular componentresponse to stressimmune responseimmune effector processcell activationcellular component organizationcell communicationcellular response to stimulusresponse to external stimulusresponse to chemicalregulation of biological qualitycoagulationresponse to biotic stimulusresponse to abiotic stimulustissue migrationcytokine productionepithelial cell proliferationdevelopmental maturationestablishment of localizationsystem processcell deathresponse to estrogencell adhesioncell cycledevelopmental growthmethylationresponse to endogenous stimulusmacromolecule localizationdemethylationestablishment or maintenance of cell polarityproduction of molecular mediator of immune responseregulation of molecular functionnitnitrogen compound metabolic processbiobiosynthetic processcelcellular metabolic processpriprimary metabolic processorgorganic substance metabolic processanaanatomical structure developmentcelcellular developmental processloclocalization of cellmovmovement of cell or subcellular componentresresponse to stressimmimmune responseimmimmune effector processcelcell activationcelcellular component organizationcelcell communicationcelcellular response to stimulusresresponse to external stimulusresresponse to chemicalregregulation of biological qualitycoacoagulationresresponse to biotic stimulusresresponse to abiotic stimulustistissue migrationcytcytokine productionepiepithelial cell proliferationdevdevelopmental maturationestestablishment of localizationsyssystem processcelcell deathresresponse to estrogencelcell adhesioncelcell cycledevdevelopmental growthmetmethylationresresponse to endogenous stimulusmacmacromolecule localizationdemdemethylationestestablishment or maintenance of cell polarityproproduction of molecular mediator of immune responseregregulation of molecular function
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription factor activity, protein bindingtranscription coregulator activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription factor activity, protein bindingtranscription coregulator activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription factor activity, protein bindingtranscription coregulator activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription factor activity, protein bindingtranscription coregulator activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription factor activity, protein bindingtranscription coregulator activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription factor activity, protein bindingtranscription coregulator activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription factor activity, protein bindingtranscription coregulator activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription factor activity, protein bindingtranscription coregulator activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription factor activity, protein bindingtranscription coregulator activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitytranscription factor activity, protein bindingtranscription coregulator activityprotein bindingion bindingorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingDNA-binding transcriDNA-binding transcription factor activitytranscription factortranscription factor activity, protein bindingtranscription coregutranscription coregulator activityprotein bindingprotein bindingion bindingion binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001709 cell fate determination ISS
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0001806 type IV hypersensitivity IEA
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0001823 mesonephros development ISS
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0002572 pro-T cell differentiation IEA
 biological_processGO:0003180 aortic valve morphogenesis ISS
 biological_processGO:0003215 cardiac right ventricle morphogenesis ISS
 biological_processGO:0003281 ventricular septum development ISS
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006952 defense response TAS
 biological_processGO:0006959 humoral immune response IEA
 biological_processGO:0007165 signal transduction ISS
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007507 heart development IBA
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0008584 male gonad development ISS
 biological_processGO:0009615 response to virus IEP
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0009887 animal organ morphogenesis IBA
 biological_processGO:0009888 tissue development IBA
 biological_processGO:0009967 positive regulation of signal transduction IMP
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IMP
 biological_processGO:0010975 regulation of neuron projection development IEA
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling ISS
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030218 erythrocyte differentiation IEA
 biological_processGO:0031929 TOR signaling ISS
 biological_processGO:0032689 negative regulation of interferon-gamma production IEA
 biological_processGO:0032703 negative regulation of interleukin-2 production IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production ISS
 biological_processGO:0033600 negative regulation of mammary gland epithelial cell proliferation IDA
 biological_processGO:0035162 embryonic hemopoiesis IEA
 biological_processGO:0035457 cellular response to interferon-alpha IEP
 biological_processGO:0035799 ureter maturation IEA
 biological_processGO:0035898 parathyroid hormone secretion IEA
 biological_processGO:0042035 regulation of cytokine biosynthetic process ISS
 biological_processGO:0042421 norepinephrine biosynthetic process ISS
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation IEA
 biological_processGO:0043523 regulation of neuron apoptotic process IEA
 biological_processGO:0043583 ear development IMP
 biological_processGO:0043627 response to estrogen IEP
 biological_processGO:0045061 thymic T cell selection IEA
 biological_processGO:0045064 T-helper 2 cell differentiation IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045582 positive regulation of T cell differentiation ISS
 biological_processGO:0045599 negative regulation of fat cell differentiation IMP
 biological_processGO:0045786 negative regulation of cell cycle IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0048468 cell development IBA
 biological_processGO:0048469 cell maturation IEA
 biological_processGO:0048485 sympathetic nervous system development ISS
 biological_processGO:0048538 thymus development IEA
 biological_processGO:0048565 digestive tract development IBA
 biological_processGO:0048589 developmental growth IEA
 biological_processGO:0048646 anatomical structure formation involved in morphogenesis ISS
 biological_processGO:0050728 negative regulation of inflammatory response IMP
 biological_processGO:0050852 T cell receptor signaling pathway ISS
 biological_processGO:0051569 regulation of histone H3-K4 methylation IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IMP
 biological_processGO:0060017 parathyroid gland development IEA
 biological_processGO:0060037 pharyngeal system development ISS
 biological_processGO:0060065 uterus development ISS
 biological_processGO:0060231 mesenchymal to epithelial transition IDA
 biological_processGO:0060374 mast cell differentiation IEA
 biological_processGO:0060676 ureteric bud formation ISS
 biological_processGO:0061085 regulation of histone H3-K27 methylation IEA
 biological_processGO:0061290 canonical Wnt signaling pathway involved in metanephric kidney development ISS
 biological_processGO:0071353 cellular response to interleukin-4 IEP
 biological_processGO:0071356 cellular response to tumor necrosis factor IEP
 biological_processGO:0071442 positive regulation of histone H3-K14 acetylation IEA
 biological_processGO:0071599 otic vesicle development IEA
 biological_processGO:0071773 cellular response to BMP stimulus IEA
 biological_processGO:0072107 positive regulation of ureteric bud formation ISS
 biological_processGO:0072178 nephric duct morphogenesis ISS
 biological_processGO:0072179 nephric duct formation ISS
 biological_processGO:0072182 regulation of nephron tubule epithelial cell differentiation ISS
 biological_processGO:0072602 interleukin-4 secretion IEA
 biological_processGO:0072643 interferon-gamma secretion IEA
 biological_processGO:0072676 lymphocyte migration IDA
 biological_processGO:0090102 cochlea development IEA
 biological_processGO:1901536 negative regulation of DNA demethylation IEA
 biological_processGO:1902036 regulation of hematopoietic stem cell differentiation TAS
 biological_processGO:2000114 regulation of establishment of cell polarity IEA
 biological_processGO:2000146 negative regulation of cell motility IMP
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IMP
 biological_processGO:2000553 positive regulation of T-helper 2 cell cytokine production IEA
 biological_processGO:2000607 negative regulation of cell proliferation involved in mesonephros development ISS
 biological_processGO:2000611 positive regulation of thyroid hormone generation IMP
 biological_processGO:2000617 positive regulation of histone H3-K9 acetylation IEA
 biological_processGO:2000664 positive regulation of interleukin-5 secretion IDA
 biological_processGO:2000667 positive regulation of interleukin-13 secretion IMP
 biological_processGO:2000679 positive regulation of transcription regulatory region DNA binding IMP
 biological_processGO:2000683 regulation of cellular response to X-ray IMP
 biological_processGO:2000703 negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation ISS
 biological_processGO:2000734 negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation ISS
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IMP
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0005134 interleukin-2 receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0070888 E-box binding IDA
 molecular_functionGO:0071837 HMG box domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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