2660


Homo sapiens (NCBI)

Features
Gene ID: 2660
  
Biological name :
  
Synonyms : GDF8|MSLHP / MSTN / myostatin
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207145_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4885259
RefSeq - NC_000002.12
RefSeq - NG_009800.1
RefSeq - NP_005250.1
RefSeq - NM_005259.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000138379 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0007517 muscle organ development TAS
 biological_processGO:0009408 response to heat IEA
 biological_processGO:0009629 response to gravity IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0014732 skeletal muscle atrophy IEA
 biological_processGO:0014741 negative regulation of muscle hypertrophy IEA
 biological_processGO:0014850 response to muscle activity IEA
 biological_processGO:0022602 ovulation cycle process IEA
 biological_processGO:0033574 response to testosterone IEA
 biological_processGO:0033673 negative regulation of kinase activity IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043403 skeletal muscle tissue regeneration IEA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045662 negative regulation of myoblast differentiation IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IEA
 biological_processGO:0046716 muscle cell cellular homeostasis IDA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0048632 negative regulation of skeletal muscle tissue growth IMP
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IDA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 biological_processGO:0071549 cellular response to dexamethasone stimulus IEA
 biological_processGO:1902723 negative regulation of skeletal muscle satellite cell proliferation ISS
 biological_processGO:1902725 negative regulation of satellite cell differentiation ISS
 biological_processGO:2000818 negative regulation of myoblast proliferation ISS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr