27429


Homo sapiens (NCBI)

Features
Gene ID: 27429
  
Biological name :
  
Synonyms : HTRA2 / HtrA serine peptidase 2 / MGCA8|OMI|PARK13|PRSS25
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203089_s_at (Human Genome U133 Plus 2.0 Array)   211152_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001308656.1
RefSeq - NP_001308657.1
RefSeq - NP_037379.1
RefSeq - NP_659540.1
RefSeq - NG_012163.1
RefSeq - NG_033037.1
RefSeq - 1012282651
RefSeq - 1012282649
RefSeq - 21614538
RefSeq - 7019477
RefSeq - NC_000002.12
RefSeq - NR_135772.1
RefSeq - NM_001321727.1
RefSeq - NM_001321728.1
RefSeq - NM_013247.4
RefSeq - NM_145074.2
RefSeq - NR_135769.1
RefSeq - NR_135770.1
RefSeq - NR_135771.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000115317 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis TAS
 biological_processGO:0006672 ceramide metabolic process IEA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0007628 adult walking behavior IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IMP
 biological_processGO:0009635 response to herbicide IEA
 biological_processGO:0010822 positive regulation of mitochondrion organization IMP
 biological_processGO:0010942 positive regulation of cell death IDA
 biological_processGO:0016540 protein autoprocessing TAS
 biological_processGO:0019742 pentacyclic triterpenoid metabolic process IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0034599 cellular response to oxidative stress NAS
 biological_processGO:0034605 cellular response to heat IDA
 biological_processGO:0035458 cellular response to interferon-beta IDA
 biological_processGO:0040014 regulation of multicellular organism growth IEA
 biological_processGO:0043065 positive regulation of apoptotic process TAS
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0044257 cellular protein catabolic process IDA
 biological_processGO:0045786 negative regulation of cell cycle TAS
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0070207 protein homotrimerization IMP
 biological_processGO:0071300 cellular response to retinoic acid IDA
 biological_processGO:0071363 cellular response to growth factor stimulus IMP
 biological_processGO:0097194 execution phase of apoptosis TAS
 biological_processGO:1901215 negative regulation of neuron death TAS
 biological_processGO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway NAS
 biological_processGO:1903146 regulation of autophagy of mitochondrion TAS
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion HMP
 biological_processGO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization IEA
 biological_processGO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IMP
 biological_processGO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IMP
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005758 mitochondrial intermembrane space IDA
 cellular_componentGO:0005783 endoplasmic reticulum NAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IDA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0035631 CD40 receptor complex ISS
 cellular_componentGO:1905370 serine-type endopeptidase complex IMP
 molecular_functionGO:0004252 serine-type endopeptidase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IMP
 molecular_functionGO:0008236 serine-type peptidase activity TAS
 molecular_functionGO:0042802 identical protein binding IMP
 molecular_functionGO:0051082 unfolded protein binding NAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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