2885


Homo sapiens (NCBI)

Features
Gene ID: 2885
  
Biological name :
  
Synonyms : ASH|EGFRBP-GRB2|Grb3-3|MST084|MSTP084|NCKAP2 / GRB2 / growth factor receptor bound protein 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 215075_s_at (Human Genome U133 Plus 2.0 Array)   223049_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4504111
RefSeq - 45359859
RefSeq - NC_000017.11
RefSeq - NG_029556.1
RefSeq - NP_002077.1
RefSeq - NP_987102.1
RefSeq - NM_002086.4
RefSeq - NM_203506.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000177885 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway TAS
 biological_processGO:0007265 Ras protein signal transduction TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0007568 aging IEA
 biological_processGO:0008286 insulin receptor signaling pathway TAS
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0031295 T cell costimulation TAS
 biological_processGO:0031623 receptor internalization IMP
 biological_processGO:0035635 entry of bacterium into host cell TAS
 biological_processGO:0035723 interleukin-15-mediated signaling pathway TAS
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0038128 ERBB2 signaling pathway TAS
 biological_processGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway TAS
 biological_processGO:0042770 signal transduction in response to DNA damage IMP
 biological_processGO:0043408 regulation of MAPK cascade IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048011 neurotrophin TRK receptor signaling pathway TAS
 biological_processGO:0048646 anatomical structure formation involved in morphogenesis IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060670 branching involved in labyrinthine layer morphogenesis IEA
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0071479 cellular response to ionizing radiation IMP
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0008180 COP9 signalosome IDA
 cellular_componentGO:0012506 vesicle membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070436 Grb2-EGFR complex IDA
 molecular_functionGO:0001784 phosphotyrosine residue binding IPI
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity TAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005154 epidermal growth factor receptor binding IPI
 molecular_functionGO:0005168 neurotrophin TRKA receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0017124 SH3 domain binding IDA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043560 insulin receptor substrate binding IPI
 molecular_functionGO:0046875 ephrin receptor binding IPI
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr