3156


Homo sapiens (NCBI)

Features
Gene ID: 3156
  
Biological name :
  
Synonyms : 3-hydroxy-3-methylglutaryl-CoA reductase / HMGCR / LDLCQ3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202539_s_at (Human Genome U133 Plus 2.0 Array)   202540_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1398331552
RefSeq - 196049380
RefSeq - 4557643
RefSeq - 767935800
RefSeq - 767935802
RefSeq - 767935804
RefSeq - NC_000005.10
RefSeq - NG_011449.1
RefSeq - NP_000850.1
RefSeq - NP_001124468.1
RefSeq - NP_001351116.1
RefSeq - XP_011541659.1
RefSeq - XP_011541660.1
RefSeq - XP_011541661.1
RefSeq - NM_000859.2
RefSeq - NM_001130996.1
RefSeq - NM_001364187.1
RefSeq - XM_011543357.1
RefSeq - XM_011543358.1
RefSeq - XM_011543359.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000113161 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006695 cholesterol biosynthetic process IDA
 biological_processGO:0006743 ubiquinone metabolic process IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0008299 isoprenoid biosynthetic process IBA
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0010664 negative regulation of striated muscle cell apoptotic process IEA
 biological_processGO:0010666 positive regulation of cardiac muscle cell apoptotic process IEA
 biological_processGO:0015936 coenzyme A metabolic process IEA
 biological_processGO:0016126 sterol biosynthetic process IBA
 biological_processGO:0019216 regulation of lipid metabolic process TAS
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 biological_processGO:0044255 cellular lipid metabolic process IBA
 biological_processGO:0045445 myoblast differentiation IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045540 regulation of cholesterol biosynthetic process TAS
 biological_processGO:0048643 positive regulation of skeletal muscle tissue development IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0051262 protein tetramerization IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0061045 negative regulation of wound healing IEA
 biological_processGO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0097756 negative regulation of blood vessel diameter IEA
 cellular_componentGO:0005778 peroxisomal membrane IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042282 hydroxymethylglutaryl-CoA reductase activity IDA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0050662 coenzyme binding IDA
 molecular_functionGO:0051721 protein phosphatase 2A binding IEA
 molecular_functionGO:0070402 NADPH binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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