317


Homo sapiens (NCBI)

Features
Gene ID: 317
  
Biological name :
  
Synonyms : APAF1 / APAF-1|CED4 / apoptotic peptidase activating factor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204859_s_at (Human Genome U133 Plus 2.0 Array)   211553_x_at (Human Genome U133 Plus 2.0 Array)   211554_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_037361.1
RefSeq - NP_863651.1
RefSeq - NP_863658.1
RefSeq - NP_863659.1
RefSeq - NC_000012.12
RefSeq - XP_016874739.1
RefSeq - 1034579319
RefSeq - NG_029094.1
RefSeq - 32483359
RefSeq - 32483361
RefSeq - 32483363
RefSeq - 4502123
RefSeq - 7108333
RefSeq - NP_001151.1
RefSeq - XR_429095.3
RefSeq - NM_001160.2
RefSeq - NM_013229.2
RefSeq - NM_181861.1
RefSeq - NM_181868.1
RefSeq - NM_181869.1
RefSeq - XM_017019250.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000120868 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0007568 aging IEA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c IDA
 biological_processGO:0010659 cardiac muscle cell apoptotic process IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0034349 glial cell apoptotic process IEA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043065 positive regulation of apoptotic process TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051402 neuron apoptotic process IEA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
 biological_processGO:0070317 negative regulation of G0 to G1 transition TAS
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:0072432 response to G1 DNA damage checkpoint signaling TAS
 biological_processGO:0097193 intrinsic apoptotic signaling pathway TAS
 biological_processGO:1902510 regulation of apoptotic DNA fragmentation IEA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0043293 apoptosome TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0000166 nucleotide binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process NAS
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043531 ADP binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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