335


Homo sapiens (NCBI)

Features
Gene ID: 335
  
Biological name :
  
Synonyms : apo(a) / APOA1 / apolipoprotein A1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204450_x_at (Human Genome U133 Plus 2.0 Array)   217073_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4557321
RefSeq - 966751411
RefSeq - 966751413
RefSeq - 966751415
RefSeq - NC_000011.10
RefSeq - NG_012021.1
RefSeq - NP_000030.1
RefSeq - NP_001304946.1
RefSeq - NP_001304947.1
RefSeq - NP_001304950.1
RefSeq - NM_000039.2
RefSeq - NM_001318017.1
RefSeq - NM_001318018.1
RefSeq - NM_001318021.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000118137 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process TAS
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0001935 endothelial cell proliferation IEA
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0002740 negative regulation of cytokine secretion involved in immune response IDA
 biological_processGO:0006656 phosphatidylcholine biosynthetic process IDA
 biological_processGO:0006695 cholesterol biosynthetic process IBA
 biological_processGO:0006898 receptor-mediated endocytosis TAS
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007229 integrin-mediated signaling pathway IDA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0008203 cholesterol metabolic process IMP
 biological_processGO:0008211 glucocorticoid metabolic process IEA
 biological_processGO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway IDA
 biological_processGO:0010873 positive regulation of cholesterol esterification IDA
 biological_processGO:0010903 negative regulation of very-low-density lipoprotein particle remodeling IDA
 biological_processGO:0014012 peripheral nervous system axon regeneration IEA
 biological_processGO:0018158 protein oxidation IDA
 biological_processGO:0018206 peptidyl-methionine modification IDA
 biological_processGO:0019216 regulation of lipid metabolic process TAS
 biological_processGO:0019433 triglyceride catabolic process IBA
 biological_processGO:0019915 lipid storage IEA
 biological_processGO:0030301 cholesterol transport IDA
 biological_processGO:0030325 adrenal gland development IEA
 biological_processGO:0031100 animal organ regeneration IEA
 biological_processGO:0031102 neuron projection regeneration IBA
 biological_processGO:0032374 regulation of cholesterol transport IBA
 biological_processGO:0032489 regulation of Cdc42 protein signal transduction IDA
 biological_processGO:0033344 cholesterol efflux IMP
 biological_processGO:0033700 phospholipid efflux IDA
 biological_processGO:0034115 negative regulation of heterotypic cell-cell adhesion IDA
 biological_processGO:0034371 chylomicron remodeling TAS
 biological_processGO:0034372 very-low-density lipoprotein particle remodeling IBA
 biological_processGO:0034375 high-density lipoprotein particle remodeling TAS
 biological_processGO:0034378 chylomicron assembly TAS
 biological_processGO:0034380 high-density lipoprotein particle assembly TAS
 biological_processGO:0034384 high-density lipoprotein particle clearance TAS
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IDA
 biological_processGO:0042157 lipoprotein metabolic process IBA
 biological_processGO:0042158 lipoprotein biosynthetic process IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042632 cholesterol homeostasis IMP
 biological_processGO:0043534 blood vessel endothelial cell migration IEA
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0043691 reverse cholesterol transport IMP
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0046889 positive regulation of lipid biosynthetic process IBA
 biological_processGO:0050713 negative regulation of interleukin-1 beta secretion IDA
 biological_processGO:0050728 negative regulation of inflammatory response IDA
 biological_processGO:0050821 protein stabilization IDA
 biological_processGO:0050919 negative chemotaxis IDA
 biological_processGO:0051180 vitamin transport IMP
 biological_processGO:0051345 positive regulation of hydrolase activity IDA
 biological_processGO:0051496 positive regulation of stress fiber assembly IDA
 biological_processGO:0055091 phospholipid homeostasis IDA
 biological_processGO:0060192 negative regulation of lipase activity IEA
 biological_processGO:0060354 negative regulation of cell adhesion molecule production IDA
 biological_processGO:0060761 negative regulation of response to cytokine stimulus IDA
 biological_processGO:0070328 triglyceride homeostasis IDA
 biological_processGO:0070371 ERK1 and ERK2 cascade IDA
 biological_processGO:0070508 cholesterol import IMP
 biological_processGO:1900026 positive regulation of substrate adhesion-dependent cell spreading IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005769 early endosome TAS
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0030139 endocytic vesicle IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0034361 very-low-density lipoprotein particle IDA
 cellular_componentGO:0034362 low-density lipoprotein particle IEA
 cellular_componentGO:0034363 intermediate-density lipoprotein particle IEA
 cellular_componentGO:0034364 high-density lipoprotein particle IDA
 cellular_componentGO:0034365 discoidal high-density lipoprotein particle IEA
 cellular_componentGO:0034366 spherical high-density lipoprotein particle IDA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0042627 chylomicron IBA
 cellular_componentGO:0062023 collagen-containing extracellular matrix HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071682 endocytic vesicle lumen TAS
 cellular_componentGO:0072562 blood microparticle HDA
 cellular_componentGO:1903561 extracellular vesicle HDA
 molecular_functionGO:0001540 amyloid-beta binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding IDA
 molecular_functionGO:0005548 phospholipid transporter activity IEA
 molecular_functionGO:0008035 high-density lipoprotein particle binding IEA
 molecular_functionGO:0015485 cholesterol binding IDA
 molecular_functionGO:0017127 cholesterol transporter activity IMP
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0031072 heat shock protein binding IPI
 molecular_functionGO:0034190 apolipoprotein receptor binding IPI
 molecular_functionGO:0034191 apolipoprotein A-I receptor binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0045499 chemorepellent activity IDA
 molecular_functionGO:0055102 lipase inhibitor activity IEA
 molecular_functionGO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity IDA
 molecular_functionGO:0070653 high-density lipoprotein particle receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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