3551


Homo sapiens (NCBI)

Features
Gene ID: 3551
  
Biological name :
  
Synonyms : IKBKB / IKK-beta|IKK2|IKKB|IMD15|NFKBIKB / inhibitor of nuclear factor kappa B kinase subunit beta
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209341_s_at (Human Genome U133 Plus 2.0 Array)   209342_s_at (Human Genome U133 Plus 2.0 Array)   211027_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767950859
RefSeq - 299758411
RefSeq - 338753358
RefSeq - 41352712
RefSeq - 530387747
RefSeq - 530387749
RefSeq - 530387751
RefSeq - 530387753
RefSeq - 530387755
RefSeq - 530387757
RefSeq - 530387759
RefSeq - 530387763
RefSeq - 767950854
RefSeq - 767950856
RefSeq - 1034660199
RefSeq - 767950861
RefSeq - 767950865
RefSeq - 767950867
RefSeq - NC_000008.11
RefSeq - NG_041793.1
RefSeq - NP_001177649.1
RefSeq - NP_001229707.1
RefSeq - NP_001547.1
RefSeq - XP_005273547.1
RefSeq - XP_005273548.1
RefSeq - XP_005273549.1
RefSeq - XP_005273550.1
RefSeq - XP_005273551.1
RefSeq - XP_005273552.1
RefSeq - XP_005273553.1
RefSeq - XP_005273555.1
RefSeq - XP_011542819.1
RefSeq - XP_011542820.1
RefSeq - XP_011542821.1
RefSeq - XP_011542822.1
RefSeq - XP_011542823.1
RefSeq - XP_011542824.1
RefSeq - XP_016868885.1
RefSeq - XM_005273498.4
RefSeq - XM_011544517.2
RefSeq - XM_011544518.2
RefSeq - XM_011544519.2
RefSeq - XM_011544520.2
RefSeq - XM_011544521.2
RefSeq - XM_011544522.2
RefSeq - NM_001190720.2
RefSeq - NM_001190721.1
RefSeq - NM_001190722.1
RefSeq - NM_001242778.1
RefSeq - NM_001556.2
RefSeq - XM_017013396.1
RefSeq - XR_949402.3
RefSeq - XR_001745530.2
RefSeq - NR_033818.1
RefSeq - NR_033819.1
RefSeq - NR_040009.1
RefSeq - XM_005273490.3
RefSeq - XM_005273491.5
RefSeq - XM_005273492.4
RefSeq - XM_005273493.4
RefSeq - XM_005273494.3
RefSeq - XM_005273495.2
RefSeq - XM_005273496.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000104365 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS
 biological_processGO:0002756 MyD88-independent toll-like receptor signaling pathway TAS
 biological_processGO:0006468 protein phosphorylation NAS
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0007252 I-kappaB phosphorylation IEA
 biological_processGO:0009615 response to virus TAS
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0030866 cortical actin cytoskeleton organization IMP
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IMP
 biological_processGO:0035509 negative regulation of myosin-light-chain-phosphatase activity IMP
 biological_processGO:0035666 TRIF-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0038095 Fc-epsilon receptor signaling pathway TAS
 biological_processGO:0042325 regulation of phosphorylation IDA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated NAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity TAS
 biological_processGO:0051403 stress-activated MAPK cascade TAS
 biological_processGO:0070498 interleukin-1-mediated signaling pathway TAS
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 biological_processGO:0072659 protein localization to plasma membrane IMP
 biological_processGO:1903140 regulation of establishment of endothelial barrier IMP
 biological_processGO:1903347 negative regulation of bicellular tight junction assembly IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0008385 IkappaB kinase complex TAS
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0035631 CD40 receptor complex ISS
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008384 IkappaB kinase activity TAS
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0097110 scaffold protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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