3557


Homo sapiens (NCBI)

Features
Gene ID: 3557
  
Biological name :
  
Synonyms : DIRA|ICIL-1RA|IL-1RN|IL-1ra|IL-1ra3|IL1F3|IL1RA|IRAP|MVCD4 / IL1RN / interleukin 1 receptor antagonist
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 212657_s_at (Human Genome U133 Plus 2.0 Array)   212659_s_at (Human Genome U133 Plus 2.0 Array)   216243_s_at (Human Genome U133 Plus 2.0 Array)   216244_at (Human Genome U133 Plus 2.0 Array)   216245_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 10835147
RefSeq - 27894317
RefSeq - 27894319
RefSeq - 27894321
RefSeq - 530369184
RefSeq - 767917985
RefSeq - 974576772
RefSeq - NC_000002.12
RefSeq - NG_021240.1
RefSeq - NP_000568.1
RefSeq - NP_001305843.1
RefSeq - NP_776213.1
RefSeq - NP_776214.1
RefSeq - NP_776215.1
RefSeq - XP_005263718.1
RefSeq - XP_011509423.1
RefSeq - NM_000577.4
RefSeq - NM_001318914.1
RefSeq - NM_173841.2
RefSeq - NM_173842.2
RefSeq - NM_173843.2
RefSeq - XM_011511121.1
RefSeq - XM_005263661.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000136689 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001660 fever generation IBA
 biological_processGO:0002437 inflammatory response to antigenic stimulus IBA
 biological_processGO:0002439 chronic inflammatory response to antigenic stimulus IBA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006955 immune response NAS
 biological_processGO:0007565 female pregnancy IBA
 biological_processGO:0007613 memory IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014050 negative regulation of glutamate secretion IBA
 biological_processGO:0014823 response to activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0019233 sensory perception of pain IBA
 biological_processGO:0019752 carboxylic acid metabolic process IBA
 biological_processGO:0030073 insulin secretion IEA
 biological_processGO:0030336 negative regulation of cell migration IBA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0032755 positive regulation of interleukin-6 production IBA
 biological_processGO:0034115 negative regulation of heterotypic cell-cell adhesion IDA
 biological_processGO:0042493 response to drug IBA
 biological_processGO:0042594 response to starvation IBA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IBA
 biological_processGO:0043507 positive regulation of JUN kinase activity IBA
 biological_processGO:0045837 negative regulation of membrane potential IBA
 biological_processGO:0046330 positive regulation of JNK cascade IBA
 biological_processGO:0051384 response to glucocorticoid IDA
 biological_processGO:0070498 interleukin-1-mediated signaling pathway TAS
 biological_processGO:0070555 response to interleukin-1 IBA
 biological_processGO:0070670 response to interleukin-4 IBA
 biological_processGO:0071222 cellular response to lipopolysaccharide IBA
 biological_processGO:0071874 cellular response to norepinephrine stimulus IBA
 biological_processGO:2000660 negative regulation of interleukin-1-mediated signaling pathway IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005622 intracellular NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005149 interleukin-1 receptor binding IBA
 molecular_functionGO:0005150 interleukin-1, type I receptor binding IPI
 molecular_functionGO:0005151 interleukin-1, type II receptor binding IPI
 molecular_functionGO:0005152 interleukin-1 receptor antagonist activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045352 interleukin-1 type I receptor antagonist activity IDA
 molecular_functionGO:0045353 interleukin-1 type II receptor antagonist activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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