3593


Homo sapiens (NCBI)

Features
Gene ID: 3593
  
Biological name :
  
Synonyms : CLMF|CLMF2|IL-12B|IMD28|IMD29|NKSF|NKSF2 / IL12B / interleukin 12B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207901_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 24497438
RefSeq - NC_000005.10
RefSeq - NG_009618.1
RefSeq - NP_002178.2
RefSeq - NM_002187.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000113302 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001916 positive regulation of T cell mediated cytotoxicity ISS
 biological_processGO:0002230 positive regulation of defense response to virus by host ISS
 biological_processGO:0002323 natural killer cell activation involved in immune response IEA
 biological_processGO:0002827 positive regulation of T-helper 1 type immune response ISS
 biological_processGO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target IDA
 biological_processGO:0002862 negative regulation of inflammatory response to antigenic stimulus IEA
 biological_processGO:0007050 cell cycle arrest IDA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0010224 response to UV-B IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010536 positive regulation of activation of Janus kinase activity IDA
 biological_processGO:0016477 cell migration IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0019953 sexual reproduction TAS
 biological_processGO:0030101 natural killer cell activation IDA
 biological_processGO:0032693 negative regulation of interleukin-10 production IMP
 biological_processGO:0032700 negative regulation of interleukin-17 production IDA
 biological_processGO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production IDA
 biological_processGO:0032729 positive regulation of interferon-gamma production IDA
 biological_processGO:0032733 positive regulation of interleukin-10 production TAS
 biological_processGO:0032735 positive regulation of interleukin-12 production IDA
 biological_processGO:0032740 positive regulation of interleukin-17 production IDA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IMP
 biological_processGO:0032816 positive regulation of natural killer cell activation IDA
 biological_processGO:0032819 positive regulation of natural killer cell proliferation IDA
 biological_processGO:0032946 positive regulation of mononuclear cell proliferation IMP
 biological_processGO:0034105 positive regulation of tissue remodeling IC
 biological_processGO:0034393 positive regulation of smooth muscle cell apoptotic process IDA
 biological_processGO:0035722 interleukin-12-mediated signaling pathway TAS
 biological_processGO:0035744 T-helper 1 cell cytokine production IEA
 biological_processGO:0038155 interleukin-23-mediated signaling pathway TAS
 biological_processGO:0042035 regulation of cytokine biosynthetic process TAS
 biological_processGO:0042088 T-helper 1 type immune response TAS
 biological_processGO:0042093 T-helper cell differentiation IDA
 biological_processGO:0042095 interferon-gamma biosynthetic process TAS
 biological_processGO:0042102 positive regulation of T cell proliferation IDA
 biological_processGO:0042104 positive regulation of activated T cell proliferation IDA
 biological_processGO:0042509 regulation of tyrosine phosphorylation of STAT protein IDA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IDA
 biological_processGO:0042832 defense response to protozoan IEA
 biological_processGO:0043382 positive regulation of memory T cell differentiation ISS
 biological_processGO:0044130 negative regulation of growth of symbiont in host IEA
 biological_processGO:0045078 positive regulation of interferon-gamma biosynthetic process TAS
 biological_processGO:0045672 positive regulation of osteoclast differentiation IDA
 biological_processGO:0045785 positive regulation of cell adhesion IDA
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IDA
 biological_processGO:0050671 positive regulation of lymphocyte proliferation IDA
 biological_processGO:0050729 positive regulation of inflammatory response IC
 biological_processGO:0050829 defense response to Gram-negative bacterium IDA
 biological_processGO:0051135 positive regulation of NK T cell activation IDA
 biological_processGO:0051142 positive regulation of NK T cell proliferation IDA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling TAS
 biological_processGO:2000318 positive regulation of T-helper 17 type immune response ISS
 biological_processGO:2000330 positive regulation of T-helper 17 cell lineage commitment ISS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031906 late endosome lumen TAS
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0043514 interleukin-12 complex IDA
 cellular_componentGO:0070743 interleukin-23 complex IDA
 molecular_functionGO:0004896 cytokine receptor activity IEA
 molecular_functionGO:0005125 cytokine activity IDA
 molecular_functionGO:0005143 interleukin-12 receptor binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IDA
 molecular_functionGO:0019955 cytokine binding IBA
 molecular_functionGO:0042164 interleukin-12 alpha subunit binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0045519 interleukin-23 receptor binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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