3643


Homo sapiens (NCBI)

Features
Gene ID: 3643
  
Biological name :
  
Synonyms : CD220|HHF5 / INSR / insulin receptor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207851_s_at (Human Genome U133 Plus 2.0 Array)   213792_s_at (Human Genome U133 Plus 2.0 Array)   226212_s_at (Human Genome U133 Plus 2.0 Array)   226216_at (Human Genome U133 Plus 2.0 Array)   226450_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034607804
RefSeq - 1034607806
RefSeq - 119395736
RefSeq - 119395738
RefSeq - NC_000019.10
RefSeq - NG_008852.2
RefSeq - NP_000199.2
RefSeq - NP_001073285.1
RefSeq - XP_011526290.2
RefSeq - XP_011526291.2
RefSeq - NM_000208.3
RefSeq - NM_001079817.2
RefSeq - XM_011527988.2
RefSeq - XM_011527989.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000171105 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IMP
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007612 learning TAS
 biological_processGO:0007613 memory TAS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008286 insulin receptor signaling pathway TAS
 biological_processGO:0008544 epidermis development IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0019087 transformation of host cell by virus IMP
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030238 male sex determination IEA
 biological_processGO:0030325 adrenal gland development IEA
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0031017 exocrine pancreas development IEA
 biological_processGO:0032147 activation of protein kinase activity IMP
 biological_processGO:0032148 activation of protein kinase B activity IDA
 biological_processGO:0032869 cellular response to insulin stimulus IDA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IEA
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043243 positive regulation of protein complex disassembly ISS
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IMP
 biological_processGO:0045725 positive regulation of glycogen biosynthetic process IDA
 biological_processGO:0045821 positive regulation of glycolytic process IMP
 biological_processGO:0045840 positive regulation of mitotic nuclear division IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045995 regulation of embryonic development IMP
 biological_processGO:0046326 positive regulation of glucose import NAS
 biological_processGO:0046777 protein autophosphorylation IMP
 biological_processGO:0048639 positive regulation of developmental growth IMP
 biological_processGO:0051290 protein heterotetramerization IDA
 biological_processGO:0051446 positive regulation of meiotic cell cycle IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IMP
 biological_processGO:0060267 positive regulation of respiratory burst IDA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 biological_processGO:0097062 dendritic spine maintenance ISS
 biological_processGO:0097242 amyloid-beta clearance ISS
 biological_processGO:1990535 neuron projection maintenance ISS
 biological_processGO:2000194 regulation of female gonad development IEA
 cellular_componentGO:0005622 intracellular ISS
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005899 insulin receptor complex IMP
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0009897 external side of plasma membrane ISS
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030424 axon IBA
 cellular_componentGO:0031981 nuclear lumen IDA
 cellular_componentGO:0032590 dendrite membrane ISS
 cellular_componentGO:0032809 neuronal cell body membrane ISS
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001540 amyloid-beta binding IPI
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IMP
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005009 insulin-activated receptor activity IDA
 molecular_functionGO:0005159 insulin-like growth factor receptor binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0005525 GTP binding IDA
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0031994 insulin-like growth factor I binding IPI
 molecular_functionGO:0031995 insulin-like growth factor II binding IPI
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IPI
 molecular_functionGO:0043559 insulin binding IPI
 molecular_functionGO:0043560 insulin receptor substrate binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IPI
 molecular_functionGO:0051425 PTB domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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