3661


Homo sapiens (NCBI)

Features
Gene ID: 3661
  
Biological name :
  
Synonyms : IIAE7 / interferon regulatory factor 3 / IRF3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202621_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4504725
RefSeq - 1034607810
RefSeq - 1370475055
RefSeq - 1370475057
RefSeq - 1370475065
RefSeq - 1370475067
RefSeq - 1370475069
RefSeq - 1370475071
RefSeq - 1370475073
RefSeq - 308199446
RefSeq - 308199448
RefSeq - 308199450
RefSeq - 308199452
RefSeq - 308199454
RefSeq - 308199456
RefSeq - 308199458
RefSeq - 1034607808
RefSeq - 578834417
RefSeq - 578834419
RefSeq - 578834423
RefSeq - 578834426
RefSeq - NC_000019.10
RefSeq - NG_031810.1
RefSeq - NP_001184051.1
RefSeq - NP_001184052.1
RefSeq - NP_001184053.1
RefSeq - NP_001184054.1
RefSeq - NP_001184055.1
RefSeq - NP_001184056.1
RefSeq - NP_001184057.1
RefSeq - NP_001562.1
RefSeq - XP_006723260.1
RefSeq - XP_006723261.1
RefSeq - XP_006723263.1
RefSeq - XP_006723264.1
RefSeq - XP_016882255.1
RefSeq - XP_016882256.1
RefSeq - XP_024307260.1
RefSeq - XP_024307261.1
RefSeq - XP_024307262.1
RefSeq - XP_024307263.1
RefSeq - XP_024307264.1
RefSeq - XP_024307265.1
RefSeq - XP_024307266.1
RefSeq - XM_017026766.2
RefSeq - XM_017026767.2
RefSeq - XM_024451492.1
RefSeq - XM_024451493.1
RefSeq - XM_024451494.1
RefSeq - NM_001197122.1
RefSeq - NM_001197123.1
RefSeq - NM_001197124.1
RefSeq - NM_001197125.1
RefSeq - NM_001197126.1
RefSeq - NM_001197127.1
RefSeq - NM_001197128.1
RefSeq - NM_001571.5
RefSeq - XM_024451495.1
RefSeq - XM_024451496.1
RefSeq - XM_024451497.1
RefSeq - XM_024451498.1
RefSeq - XR_002958312.1
RefSeq - XR_001753678.1
RefSeq - XR_002958310.1
RefSeq - XR_002958311.1
RefSeq - NR_045568.1
RefSeq - XM_006723197.1
RefSeq - XM_006723198.2
RefSeq - XM_006723200.1
RefSeq - XM_006723201.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000126456 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032479 regulation of type I interferon production TAS
 biological_processGO:0032480 negative regulation of type I interferon production TAS
 biological_processGO:0032481 positive regulation of type I interferon production TAS
 biological_processGO:0032727 positive regulation of interferon-alpha production ISS
 biological_processGO:0032728 positive regulation of interferon-beta production TAS
 biological_processGO:0035666 TRIF-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0039530 MDA-5 signaling pathway TAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043330 response to exogenous dsRNA IEA
 biological_processGO:0045351 type I interferon biosynthetic process IEA
 biological_processGO:0045358 negative regulation of interferon-beta biosynthetic process IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0050689 negative regulation of defense response to virus by host IEA
 biological_processGO:0050715 positive regulation of cytokine secretion IEA
 biological_processGO:0051607 defense response to virus ISS
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway TAS
 biological_processGO:0060337 type I interferon signaling pathway TAS
 biological_processGO:0060340 positive regulation of type I interferon-mediated signaling pathway IEA
 biological_processGO:0071359 cellular response to dsRNA IEA
 biological_processGO:0071888 macrophage apoptotic process TAS
 biological_processGO:0097300 programmed necrotic cell death IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IC
 molecular_functionGO:0003677 DNA binding NAS
 molecular_functionGO:0003712 transcription coregulator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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