3670


Homo sapiens (NCBI)

Features
Gene ID: 3670
  
Biological name :
  
Synonyms : ISL1 / ISLET1|Isl-1 / ISL LIM homeobox 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206104_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 115387114
RefSeq - 767935853
RefSeq - NC_000005.10
RefSeq - NG_023040.1
RefSeq - NP_002193.2
RefSeq - XP_011541682.1
RefSeq - NM_002202.2
RefSeq - XM_011543380.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000016082 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0001755 neural crest cell migration IEA
 biological_processGO:0003139 secondary heart field specification IMP
 biological_processGO:0003148 outflow tract septum morphogenesis ISS
 biological_processGO:0003151 outflow tract morphogenesis ISS
 biological_processGO:0003203 endocardial cushion morphogenesis ISS
 biological_processGO:0003215 cardiac right ventricle morphogenesis ISS
 biological_processGO:0003266 regulation of secondary heart field cardioblast proliferation IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007507 heart development ISS
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production ISS
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0021520 spinal cord motor neuron cell fate specification IEA
 biological_processGO:0021522 spinal cord motor neuron differentiation ISS
 biological_processGO:0021524 visceral motor neuron differentiation IEA
 biological_processGO:0021559 trigeminal nerve development ISS
 biological_processGO:0021983 pituitary gland development IEA
 biological_processGO:0031016 pancreas development ISS
 biological_processGO:0031103 axon regeneration IEA
 biological_processGO:0031290 retinal ganglion cell axon guidance IEA
 biological_processGO:0032024 positive regulation of insulin secretion IC
 biological_processGO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production ISS
 biological_processGO:0032729 positive regulation of interferon-gamma production ISS
 biological_processGO:0032730 positive regulation of interleukin-1 alpha production ISS
 biological_processGO:0032731 positive regulation of interleukin-1 beta production ISS
 biological_processGO:0032735 positive regulation of interleukin-12 production ISS
 biological_processGO:0032755 positive regulation of interleukin-6 production ISS
 biological_processGO:0032760 positive regulation of tumor necrosis factor production ISS
 biological_processGO:0033147 negative regulation of intracellular estrogen receptor signaling pathway ISS
 biological_processGO:0035066 positive regulation of histone acetylation IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0043388 positive regulation of DNA binding IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISS
 biological_processGO:0045597 positive regulation of cell differentiation ISS
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045766 positive regulation of angiogenesis ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0048665 neuron fate specification ISS
 biological_processGO:0048762 mesenchymal cell differentiation ISS
 biological_processGO:0048880 sensory system development ISS
 biological_processGO:0048936 peripheral nervous system neuron axonogenesis ISS
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0050728 negative regulation of inflammatory response ISS
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis ISS
 biological_processGO:0060037 pharyngeal system development ISS
 biological_processGO:0060379 cardiac muscle cell myoblast differentiation IEA
 biological_processGO:0060384 innervation ISS
 biological_processGO:0060413 atrial septum morphogenesis ISS
 biological_processGO:0060913 cardiac cell fate determination IDA
 biological_processGO:0071385 cellular response to glucocorticoid stimulus ISS
 biological_processGO:0071657 positive regulation of granulocyte colony-stimulating factor production ISS
 biological_processGO:0090074 negative regulation of protein homodimerization activity ISS
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1901258 positive regulation of macrophage colony-stimulating factor production ISS
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm NAS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IPI
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding NAS
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016922 nuclear receptor binding ISS
 molecular_functionGO:0030331 estrogen receptor binding ISS
 molecular_functionGO:0043425 bHLH transcription factor binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1990841 promoter-specific chromatin binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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