3718


Homo sapiens (NCBI)

Features
Gene ID: 3718
  
Biological name :
  
Synonyms : JAK3 / JAK-3|JAK3_HUMAN|JAKL|L-JAK|LJAK / Janus kinase 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207187_at (Human Genome U133 Plus 2.0 Array)   211108_s_at (Human Genome U133 Plus 2.0 Array)   211109_at (Human Genome U133 Plus 2.0 Array)   227677_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_011526293.1
RefSeq - 530414824
RefSeq - 768002308
RefSeq - 768002312
RefSeq - NC_000019.10
RefSeq - NG_007273.1
RefSeq - NP_000206.2
RefSeq - XP_005259953.1
RefSeq - XP_011526292.1
RefSeq - 47157315
RefSeq - NM_000215.3
RefSeq - XM_011527991.2
RefSeq - XM_005259896.3
RefSeq - XM_011527990.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000105639 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002731 negative regulation of dendritic cell cytokine production ISS
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0007167 enzyme linked receptor protein signaling pathway ISS
 biological_processGO:0007260 tyrosine phosphorylation of STAT protein TAS
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030183 B cell differentiation ISS
 biological_processGO:0030218 erythrocyte differentiation IBA
 biological_processGO:0032693 negative regulation of interleukin-10 production ISS
 biological_processGO:0032695 negative regulation of interleukin-12 production ISS
 biological_processGO:0035556 intracellular signal transduction ISS
 biological_processGO:0035723 interleukin-15-mediated signaling pathway TAS
 biological_processGO:0035771 interleukin-4-mediated signaling pathway IDA
 biological_processGO:0038110 interleukin-2-mediated signaling pathway TAS
 biological_processGO:0038111 interleukin-7-mediated signaling pathway TAS
 biological_processGO:0038113 interleukin-9-mediated signaling pathway TAS
 biological_processGO:0038114 interleukin-21-mediated signaling pathway TAS
 biological_processGO:0042102 positive regulation of T cell proliferation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043029 T cell homeostasis TAS
 biological_processGO:0045221 negative regulation of FasL biosynthetic process ISS
 biological_processGO:0045626 negative regulation of T-helper 1 cell differentiation ISS
 biological_processGO:0046425 regulation of JAK-STAT cascade TAS
 biological_processGO:0050868 negative regulation of T cell activation ISS
 biological_processGO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway TAS
 biological_processGO:0070232 regulation of T cell apoptotic process ISS
 biological_processGO:0070244 negative regulation of thymocyte apoptotic process ISS
 biological_processGO:0070669 response to interleukin-2 TAS
 biological_processGO:0070670 response to interleukin-4 IDA
 biological_processGO:0070672 response to interleukin-15 TAS
 biological_processGO:0071104 response to interleukin-9 TAS
 cellular_componentGO:0005768 endosome TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019903 protein phosphatase binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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