388585


Homo sapiens (NCBI)

Features
Gene ID: 388585
  
Biological name :
  
Synonyms : bHLHb38 / HES5 / hes family bHLH transcription factor 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 239230_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_005244808.1
RefSeq - 58219048
RefSeq - NC_000001.11
RefSeq - NT_187515.1
RefSeq - 530360315
RefSeq - NP_001010926.1
RefSeq - NM_001010926.3
RefSeq - XM_005244751.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000197921 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0001756 somitogenesis IBA
 biological_processGO:0002062 chondrocyte differentiation ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0007155 cell adhesion ISS
 biological_processGO:0007219 Notch signaling pathway TAS
 biological_processGO:0007224 smoothened signaling pathway ISS
 biological_processGO:0007420 brain development ISS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0014003 oligodendrocyte development ISS
 biological_processGO:0021537 telencephalon development ISS
 biological_processGO:0021781 glial cell fate commitment ISS
 biological_processGO:0021861 forebrain radial glial cell differentiation IEA
 biological_processGO:0021915 neural tube development ISS
 biological_processGO:0022010 central nervous system myelination ISS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030513 positive regulation of BMP signaling pathway ISS
 biological_processGO:0031641 regulation of myelination ISS
 biological_processGO:0042491 inner ear auditory receptor cell differentiation ISS
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ISS
 biological_processGO:0042668 auditory receptor cell fate determination IEA
 biological_processGO:0043010 camera-type eye development ISS
 biological_processGO:0045595 regulation of cell differentiation ISS
 biological_processGO:0045607 regulation of inner ear auditory receptor cell differentiation IEA
 biological_processGO:0045665 negative regulation of neuron differentiation ISS
 biological_processGO:0045747 positive regulation of Notch signaling pathway IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046427 positive regulation of JAK-STAT cascade ISS
 biological_processGO:0048469 cell maturation ISS
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IGI
 biological_processGO:0048708 astrocyte differentiation ISS
 biological_processGO:0048712 negative regulation of astrocyte differentiation ISS
 biological_processGO:0048715 negative regulation of oligodendrocyte differentiation ISS
 biological_processGO:0050678 regulation of epithelial cell proliferation IEA
 biological_processGO:0050767 regulation of neurogenesis ISS
 biological_processGO:0051216 cartilage development IDA
 biological_processGO:0060122 inner ear receptor cell stereocilium organization IEA
 biological_processGO:0065003 protein-containing complex assembly ISS
 biological_processGO:0072049 comma-shaped body morphogenesis IEA
 biological_processGO:0072050 S-shaped body morphogenesis IEA
 biological_processGO:0072086 specification of loop of Henle identity IEA
 biological_processGO:0072282 metanephric nephron tubule morphogenesis IEA
 biological_processGO:0090162 establishment of epithelial cell polarity IEA
 biological_processGO:0097150 neuronal stem cell population maintenance IEP
 biological_processGO:2000737 negative regulation of stem cell differentiation IMP
 biological_processGO:2000974 negative regulation of pro-B cell differentiation ISS
 biological_processGO:2000978 negative regulation of forebrain neuron differentiation IEA
 biological_processGO:2000981 negative regulation of inner ear receptor cell differentiation IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISS
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0008134 transcription factor binding NAS
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:1990837 sequence-specific double-stranded DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr