3932


Homo sapiens (NCBI)

Features
Gene ID: 3932
  
Biological name :
  
Synonyms : IMD22|LSK|YT16|p56lck|pp58lck / LCK / LCK proto-oncogene, Src family tyrosine kinase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204890_s_at (Human Genome U133 Plus 2.0 Array)   204891_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1060099306
RefSeq - 112789546
RefSeq - 112789548
RefSeq - 1370453118
RefSeq - 1370453120
RefSeq - 767904315
RefSeq - NC_000001.11
RefSeq - NG_023387.1
RefSeq - NP_001036236.1
RefSeq - NP_001317397.1
RefSeq - NP_005347.3
RefSeq - XP_011539755.1
RefSeq - XP_024302814.1
RefSeq - XP_024302815.1
RefSeq - NM_001042771.2
RefSeq - NM_001330468.1
RefSeq - NM_005356.4
RefSeq - XM_011541453.3
RefSeq - XM_024447046.1
RefSeq - XM_024447047.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000182866 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0006882 cellular zinc ion homeostasis ISS
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process ISS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IMP
 biological_processGO:0030097 hemopoiesis NAS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030217 T cell differentiation ISS
 biological_processGO:0031295 T cell costimulation TAS
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042493 response to drug ISS
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0050690 regulation of defense response to virus by virus TAS
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0050862 positive regulation of T cell receptor signaling pathway NAS
 biological_processGO:0050870 positive regulation of T cell activation ISS
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051209 release of sequestered calcium ion into cytosol ISS
 biological_processGO:0051249 regulation of lymphocyte activation NAS
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway ISS
 cellular_componentGO:0000242 pericentriolar material ISS
 cellular_componentGO:0001772 immunological synapse IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 cellular_componentGO:0045121 membrane raft ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001784 phosphotyrosine residue binding IPI
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IBA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity ISS
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0016301 kinase activity TAS
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0042169 SH2 domain binding ISS
 molecular_functionGO:0042608 T cell receptor binding IPI
 molecular_functionGO:0042609 CD4 receptor binding IPI
 molecular_functionGO:0042610 CD8 receptor binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IPI
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0051117 ATPase binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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