3981


Homo sapiens (NCBI)

Features
Gene ID: 3981
  
Biological name :
  
Synonyms : DNA ligase 4 / LIG4 / LIG4S
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206235_at (Human Genome U133 Plus 2.0 Array)   227766_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 148539894
RefSeq - 1034584382
RefSeq - 1034584384
RefSeq - 1034584388
RefSeq - 1034584398
RefSeq - 1034584403
RefSeq - 1060085929
RefSeq - 1207996436
RefSeq - 1207996517
RefSeq - 1207996521
RefSeq - 1207996525
RefSeq - 1207996529
RefSeq - 1207996540
RefSeq - 1207996561
RefSeq - 1034584380
RefSeq - 23199993
RefSeq - 46255052
RefSeq - 530423364
RefSeq - 530423368
RefSeq - 578825259
RefSeq - NC_000013.11
RefSeq - NG_007396.1
RefSeq - NP_001091738.1
RefSeq - NP_001317524.1
RefSeq - NP_001339527.1
RefSeq - NP_001339528.1
RefSeq - NP_001339529.1
RefSeq - NP_001339530.1
RefSeq - NP_001339531.1
RefSeq - NP_001339532.1
RefSeq - NP_001339533.1
RefSeq - NP_002303.2
RefSeq - NP_996820.1
RefSeq - XP_005254113.1
RefSeq - XP_005254115.1
RefSeq - XP_006720014.1
RefSeq - XP_016876053.1
RefSeq - XP_016876054.1
RefSeq - XP_016876055.1
RefSeq - XP_016876057.1
RefSeq - XP_016876060.1
RefSeq - XP_016876062.1
RefSeq - NM_001098268.1
RefSeq - NM_001330595.1
RefSeq - NM_001352598.1
RefSeq - NM_001352599.1
RefSeq - NM_001352600.1
RefSeq - NM_001352601.1
RefSeq - NM_001352602.1
RefSeq - NM_001352603.1
RefSeq - NM_001352604.1
RefSeq - NM_002312.3
RefSeq - NM_206937.1
RefSeq - XM_017020571.1
RefSeq - XM_017020573.1
RefSeq - XM_005254056.1
RefSeq - XM_005254058.4
RefSeq - XM_006719951.3
RefSeq - XM_017020564.1
RefSeq - XM_017020565.1
RefSeq - XM_017020566.1
RefSeq - XM_017020568.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000174405 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000012 single strand break repair IDA
 biological_processGO:0001701 in utero embryonic development ISS
 biological_processGO:0002328 pro-B cell differentiation ISS
 biological_processGO:0006266 DNA ligation IDA
 biological_processGO:0006297 nucleotide-excision repair, DNA gap filling IDA
 biological_processGO:0006302 double-strand break repair ISS
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007417 central nervous system development ISS
 biological_processGO:0008283 cell proliferation ISS
 biological_processGO:0010165 response to X-ray IMP
 biological_processGO:0010332 response to gamma radiation ISS
 biological_processGO:0033077 T cell differentiation in thymus ISS
 biological_processGO:0033151 V(D)J recombination IDA
 biological_processGO:0033152 immunoglobulin V(D)J recombination IBA
 biological_processGO:0033153 T cell receptor V(D)J recombination ISS
 biological_processGO:0035019 somatic stem cell population maintenance ISS
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISS
 biological_processGO:0045190 isotype switching ISS
 biological_processGO:0048146 positive regulation of fibroblast proliferation ISS
 biological_processGO:0050769 positive regulation of neurogenesis ISS
 biological_processGO:0051102 DNA ligation involved in DNA recombination ISS
 biological_processGO:0051103 DNA ligation involved in DNA repair ISS
 biological_processGO:0051276 chromosome organization ISS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051402 neuron apoptotic process ISS
 biological_processGO:0071285 cellular response to lithium ion IEA
 biological_processGO:0071897 DNA biosynthetic process IEA
 biological_processGO:0075713 establishment of integrated proviral latency TAS
 biological_processGO:0097680 double-strand break repair via classical nonhomologous end joining IMP
 biological_processGO:2001252 positive regulation of chromosome organization IMP
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IC
 cellular_componentGO:0000793 condensed chromosome IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex ISS
 cellular_componentGO:0032807 DNA ligase IV complex IMP
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IDA
 cellular_componentGO:0070419 nonhomologous end joining complex IDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003909 DNA ligase activity TAS
 molecular_functionGO:0003910 DNA ligase (ATP) activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0016874 ligase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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