4035


Homo sapiens (NCBI)

Features
Gene ID: 4035
  
Biological name :
  
Synonyms : A2MR|APOER|APR|CD91|IGFBP-3R|IGFBP3R|IGFBP3R1|KPA|LRP|LRP1A|TGFBR5 / LDL receptor related protein 1 / LRP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1555353_at (Human Genome U133 Plus 2.0 Array)   1569042_at (Human Genome U133 Plus 2.0 Array)   200784_s_at (Human Genome U133 Plus 2.0 Array)   200785_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034579538
RefSeq - 126012562
RefSeq - NC_000012.12
RefSeq - NG_016444.1
RefSeq - NP_002323.2
RefSeq - XP_016874792.1
RefSeq - NM_002332.2
RefSeq - XM_017019303.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000123384 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process TAS
 biological_processGO:0002265 astrocyte activation involved in immune response ISS
 biological_processGO:0006629 lipid metabolic process TAS
 biological_processGO:0006898 receptor-mediated endocytosis TAS
 biological_processGO:0006909 phagocytosis NAS
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0010715 regulation of extracellular matrix disassembly TAS
 biological_processGO:0010875 positive regulation of cholesterol efflux ISS
 biological_processGO:0010942 positive regulation of cell death IGI
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0014912 negative regulation of smooth muscle cell migration ISS
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway ISS
 biological_processGO:0031623 receptor internalization TAS
 biological_processGO:0032092 positive regulation of protein binding IGI
 biological_processGO:0032370 positive regulation of lipid transport ISS
 biological_processGO:0032374 regulation of cholesterol transport ISS
 biological_processGO:0032429 regulation of phospholipase A2 activity ISS
 biological_processGO:0032956 regulation of actin cytoskeleton organization ISS
 biological_processGO:0035909 aorta morphogenesis ISS
 biological_processGO:0042157 lipoprotein metabolic process IEA
 biological_processGO:0042953 lipoprotein transport NAS
 biological_processGO:0043277 apoptotic cell clearance ISS
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045056 transcytosis TAS
 biological_processGO:0045732 positive regulation of protein catabolic process ISS
 biological_processGO:0045807 positive regulation of endocytosis IGI
 biological_processGO:0051222 positive regulation of protein transport IEA
 biological_processGO:0051246 regulation of protein metabolic process ISS
 biological_processGO:0097242 amyloid-beta clearance TAS
 biological_processGO:1900223 positive regulation of amyloid-beta clearance TAS
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IGI
 biological_processGO:1904646 cellular response to amyloid-beta ISS
 biological_processGO:1905167 positive regulation of lysosomal protein catabolic process IMP
 biological_processGO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0098797 plasma membrane protein complex TAS
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005041 low-density lipoprotein particle receptor activity TAS
 molecular_functionGO:0005044 scavenger receptor activity TAS
 molecular_functionGO:0005509 calcium ion binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016964 alpha-2 macroglobulin receptor activity TAS
 molecular_functionGO:0030226 apolipoprotein receptor activity TAS
 molecular_functionGO:0032050 clathrin heavy chain binding IPI
 molecular_functionGO:0034185 apolipoprotein binding IPI
 molecular_functionGO:0038023 signaling receptor activity TAS
 molecular_functionGO:0042954 lipoprotein transporter activity NAS
 molecular_functionGO:0043395 heparan sulfate proteoglycan binding TAS
 molecular_functionGO:0044877 protein-containing complex binding IDA
 molecular_functionGO:0070325 lipoprotein particle receptor binding IC


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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