4040


Homo sapiens (NCBI)

Features
Gene ID: 4040
  
Biological name :
  
Synonyms : ADCAD2|STHAG7 / LDL receptor related protein 6 / LRP6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205606_at (Human Genome U133 Plus 2.0 Array)   225745_at (Human Genome U133 Plus 2.0 Array)   34697_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 148727288
RefSeq - 578822872
RefSeq - 767971954
RefSeq - NC_000012.12
RefSeq - NG_016168.1
RefSeq - NP_002327.2
RefSeq - NW_011332696.1
RefSeq - XP_006719141.1
RefSeq - XP_011518973.1
RefSeq - XM_011520671.3
RefSeq - NM_002336.2
RefSeq - XR_002957325.1
RefSeq - XR_429035.3
RefSeq - XM_006719078.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000070018 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001702 gastrulation with mouth forming second IBA
 biological_processGO:0001843 neural tube closure IBA
 biological_processGO:0001933 negative regulation of protein phosphorylation IMP
 biological_processGO:0003344 pericardium morphogenesis IBA
 biological_processGO:0006469 negative regulation of protein kinase activity IMP
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0009880 embryonic pattern specification IBA
 biological_processGO:0009952 anterior/posterior pattern specification IBA
 biological_processGO:0014029 neural crest formation IDA
 biological_processGO:0014033 neural crest cell differentiation IDA
 biological_processGO:0016055 Wnt signaling pathway IMP
 biological_processGO:0021587 cerebellum morphogenesis IBA
 biological_processGO:0021794 thalamus development IBA
 biological_processGO:0021987 cerebral cortex development IBA
 biological_processGO:0030278 regulation of ossification IBA
 biological_processGO:0030326 embryonic limb morphogenesis IBA
 biological_processGO:0030901 midbrain development IBA
 biological_processGO:0030917 midbrain-hindbrain boundary development IBA
 biological_processGO:0034392 negative regulation of smooth muscle cell apoptotic process IMP
 biological_processGO:0035261 external genitalia morphogenesis IBA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IBA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification IDA
 biological_processGO:0044335 canonical Wnt signaling pathway involved in neural crest cell differentiation IC
 biological_processGO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation IC
 biological_processGO:0045787 positive regulation of cell cycle IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046849 bone remodeling IBA
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IBA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0060021 roof of mouth development IBA
 biological_processGO:0060026 convergent extension IBA
 biological_processGO:0060059 embryonic retina morphogenesis in camera-type eye IBA
 biological_processGO:0060070 canonical Wnt signaling pathway TAS
 biological_processGO:0060325 face morphogenesis IBA
 biological_processGO:0060349 bone morphogenesis IBA
 biological_processGO:0060444 branching involved in mammary gland duct morphogenesis IBA
 biological_processGO:0060535 trachea cartilage morphogenesis IBA
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IGI
 biological_processGO:0071397 cellular response to cholesterol IMP
 biological_processGO:0071542 dopaminergic neuron differentiation ISS
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IDA
 biological_processGO:0072659 protein localization to plasma membrane IPI
 biological_processGO:0090009 primitive streak formation IBA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway TAS
 biological_processGO:0090118 receptor-mediated endocytosis involved in cholesterol transport IBA
 biological_processGO:0090244 Wnt signaling pathway involved in somitogenesis IBA
 biological_processGO:0090245 axis elongation involved in somitogenesis IBA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IDA
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:1901998 toxin transport IEA
 biological_processGO:1904886 beta-catenin destruction complex disassembly TAS
 biological_processGO:1904948 midbrain dopaminergic neuron differentiation TAS
 biological_processGO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation TAS
 biological_processGO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0031901 early endosome membrane TAS
 cellular_componentGO:0043025 neuronal cell body IBA
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:1990851 Wnt-Frizzled-LRP5/6 complex TAS
 cellular_componentGO:1990909 Wnt signalosome NAS
 molecular_functionGO:0005041 low-density lipoprotein particle receptor activity IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005109 frizzled binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015026 coreceptor activity IBA
 molecular_functionGO:0017147 Wnt-protein binding TAS
 molecular_functionGO:0019210 kinase inhibitor activity IMP
 molecular_functionGO:0019534 toxin transmembrane transporter activity IMP
 molecular_functionGO:0034185 apolipoprotein binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0071936 coreceptor activity involved in Wnt signaling pathway IDA
 molecular_functionGO:1904928 coreceptor activity involved in canonical Wnt signaling pathway NAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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