4087


Homo sapiens (NCBI)

Features
Gene ID: 4087
  
Biological name :
  
Synonyms : JV18|JV18-1|MADH2|MADR2|hMAD-2|hSMAD2 / SMAD2 / SMAD family member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203075_at (Human Genome U133 Plus 2.0 Array)   203076_s_at (Human Genome U133 Plus 2.0 Array)   203077_s_at (Human Genome U133 Plus 2.0 Array)   226563_at (Human Genome U133 Plus 2.0 Array)   235598_at (Human Genome U133 Plus 2.0 Array)   239271_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 530413775
RefSeq - 1034604016
RefSeq - 1034604019
RefSeq - 1034604022
RefSeq - 1034604024
RefSeq - 1034604026
RefSeq - 1370473460
RefSeq - 209693426
RefSeq - 51173730
RefSeq - 5174511
RefSeq - 1034604013
RefSeq - 578832472
RefSeq - 767998715
RefSeq - 767998717
RefSeq - NC_000018.10
RefSeq - NG_029946.1
RefSeq - NP_001003652.1
RefSeq - NP_001129409.1
RefSeq - NP_005892.1
RefSeq - XP_005258316.1
RefSeq - XP_006722514.1
RefSeq - XP_011524286.1
RefSeq - XP_011524287.1
RefSeq - XP_016881234.1
RefSeq - XP_016881235.1
RefSeq - XP_016881236.1
RefSeq - XP_016881237.1
RefSeq - XP_016881238.1
RefSeq - XP_016881239.1
RefSeq - XP_024306941.1
RefSeq - NM_001003652.3
RefSeq - NM_001135937.2
RefSeq - NM_005901.5
RefSeq - XM_017025749.1
RefSeq - XM_017025750.2
RefSeq - XM_024451173.1
RefSeq - XM_005258259.4
RefSeq - XM_006722451.4
RefSeq - XM_011525984.2
RefSeq - XM_011525985.3
RefSeq - XM_017025745.2
RefSeq - XM_017025746.2
RefSeq - XM_017025747.2
RefSeq - XM_017025748.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000175387 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0001657 ureteric bud development IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001706 endoderm formation IEA
 biological_processGO:0001707 mesoderm formation ISS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0007182 common-partner SMAD protein phosphorylation IDA
 biological_processGO:0007183 SMAD protein complex assembly IDA
 biological_processGO:0007352 zygotic specification of dorsal/ventral axis IMP
 biological_processGO:0007369 gastrulation TAS
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0009952 anterior/posterior pattern specification ISS
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition ISS
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0017015 regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IEA
 biological_processGO:0030073 insulin secretion IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030325 adrenal gland development IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0030513 positive regulation of BMP signaling pathway IMP
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0031053 primary miRNA processing TAS
 biological_processGO:0032924 activin receptor signaling pathway IMP
 biological_processGO:0035019 somatic stem cell population maintenance TAS
 biological_processGO:0035265 organ growth IEA
 biological_processGO:0035556 intracellular signal transduction ISS
 biological_processGO:0038092 nodal signaling pathway IMP
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0045165 cell fate commitment ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II TAS
 biological_processGO:0048340 paraxial mesoderm morphogenesis ISS
 biological_processGO:0048617 embryonic foregut morphogenesis IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IEA
 biological_processGO:0051098 regulation of binding ISS
 biological_processGO:0060039 pericardium development IEA
 biological_processGO:0060395 SMAD protein signal transduction IEA
 biological_processGO:0062009 secondary palate development ISS
 biological_processGO:0070723 response to cholesterol IDA
 biological_processGO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry IMP
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0032444 activin responsive factor complex IDA
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0071141 SMAD protein complex IDA
 cellular_componentGO:0071144 heteromeric SMAD protein complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISS
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0019902 phosphatase binding IPI
 molecular_functionGO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0033613 activating transcription factor binding IPI
 molecular_functionGO:0034713 type I transforming growth factor beta receptor binding IPI
 molecular_functionGO:0035326 enhancer binding IC
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046332 SMAD binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0048156 tau protein binding ISS
 molecular_functionGO:0070410 co-SMAD binding IPI
 molecular_functionGO:0070411 I-SMAD binding IPI
 molecular_functionGO:0070412 R-SMAD binding IPI
 molecular_functionGO:0070878 primary miRNA binding IPI
 molecular_functionGO:0097718 disordered domain specific binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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