4088


Homo sapiens (NCBI)

Features
Gene ID: 4088
  
Biological name :
  
Synonyms : HSPC193|HsT17436|JV15-2|LDS1C|LDS3|MADH3 / SMAD3 / SMAD family member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205396_at (Human Genome U133 Plus 2.0 Array)   205397_x_at (Human Genome U133 Plus 2.0 Array)   205398_s_at (Human Genome U133 Plus 2.0 Array)   218284_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 223029440
RefSeq - 223029442
RefSeq - 223029444
RefSeq - 5174513
RefSeq - 767984133
RefSeq - 767984135
RefSeq - NC_000015.10
RefSeq - NG_011990.1
RefSeq - NP_001138574.1
RefSeq - NP_001138575.1
RefSeq - NP_001138576.1
RefSeq - NP_005893.1
RefSeq - XP_011519861.1
RefSeq - XP_011519862.1
RefSeq - NM_001145102.1
RefSeq - NM_001145103.1
RefSeq - NM_001145104.1
RefSeq - NM_005902.3
RefSeq - XM_011521559.3
RefSeq - XM_011521560.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000166949 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0001657 ureteric bud development IEA
 biological_processGO:0001666 response to hypoxia IMP
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001707 mesoderm formation IEA
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0001947 heart looping IEA
 biological_processGO:0002076 osteoblast development IEA
 biological_processGO:0002520 immune system development IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0006955 immune response IMP
 biological_processGO:0007050 cell cycle arrest IMP
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0007183 SMAD protein complex assembly IDA
 biological_processGO:0007492 endoderm development IEA
 biological_processGO:0009880 embryonic pattern specification IEA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0010694 positive regulation of alkaline phosphatase activity IEA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0016202 regulation of striated muscle tissue development IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0017015 regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0019049 evasion or tolerance of host defenses by virus IDA
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IEA
 biological_processGO:0030308 negative regulation of cell growth IDA
 biological_processGO:0030325 adrenal gland development IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0030501 positive regulation of bone mineralization IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0030878 thyroid gland development IEA
 biological_processGO:0031053 primary miRNA processing TAS
 biological_processGO:0032332 positive regulation of chondrocyte differentiation IEA
 biological_processGO:0032731 positive regulation of interleukin-1 beta production IEA
 biological_processGO:0032909 regulation of transforming growth factor beta2 production IMP
 biological_processGO:0032916 positive regulation of transforming growth factor beta3 production IEA
 biological_processGO:0032924 activin receptor signaling pathway IMP
 biological_processGO:0033689 negative regulation of osteoblast proliferation IEA
 biological_processGO:0038092 nodal signaling pathway IMP
 biological_processGO:0042060 wound healing TAS
 biological_processGO:0042110 T cell activation IEA
 biological_processGO:0042177 negative regulation of protein catabolic process IEA
 biological_processGO:0042307 positive regulation of protein import into nucleus NAS
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045216 cell-cell junction organization IMP
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IDA
 biological_processGO:0045599 negative regulation of fat cell differentiation IDA
 biological_processGO:0045668 negative regulation of osteoblast differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045930 negative regulation of mitotic cell cycle IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II TAS
 biological_processGO:0048340 paraxial mesoderm morphogenesis IEA
 biological_processGO:0048589 developmental growth IEA
 biological_processGO:0048617 embryonic foregut morphogenesis IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IEA
 biological_processGO:0050678 regulation of epithelial cell proliferation IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0050776 regulation of immune response IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0050927 positive regulation of positive chemotaxis IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity NAS
 biological_processGO:0051098 regulation of binding IEA
 biological_processGO:0051481 negative regulation of cytosolic calcium ion concentration IDA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IEA
 biological_processGO:0060039 pericardium development IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060290 transdifferentiation IEA
 biological_processGO:0060395 SMAD protein signal transduction NAS
 biological_processGO:0061045 negative regulation of wound healing IEA
 biological_processGO:0061767 negative regulation of lung blood pressure IEA
 biological_processGO:0070306 lens fiber cell differentiation IEA
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IDA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IMP
 biological_processGO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IEA
 biological_processGO:1901203 positive regulation of extracellular matrix assembly IDA
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IMP
 biological_processGO:1903243 negative regulation of cardiac muscle hypertrophy in response to stress IEA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005637 nuclear inner membrane IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0043235 receptor complex IMP
 cellular_componentGO:0071141 SMAD protein complex IDA
 cellular_componentGO:0071144 heteromeric SMAD protein complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding IMP
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000989 transcription factor activity, transcription factor binding IDA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IPI
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0017151 DEAD/H-box RNA helicase binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019902 phosphatase binding IPI
 molecular_functionGO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity IDA
 molecular_functionGO:0031490 chromatin DNA binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0031962 mineralocorticoid receptor binding IPI
 molecular_functionGO:0035259 glucocorticoid receptor binding IPI
 molecular_functionGO:0035326 enhancer binding IC
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0043130 ubiquitin binding IDA
 molecular_functionGO:0043425 bHLH transcription factor binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070410 co-SMAD binding IPI
 molecular_functionGO:0070412 R-SMAD binding IPI
 molecular_functionGO:0070878 primary miRNA binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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