4091


Homo sapiens (NCBI)

Features
Gene ID: 4091
  
Biological name :
  
Synonyms : AOVD2|HsT17432|MADH6|MADH7 / SMAD6 / SMAD family member 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207069_s_at (Human Genome U133 Plus 2.0 Array)   209886_s_at (Human Genome U133 Plus 2.0 Array)   209887_at (Human Genome U133 Plus 2.0 Array)   213565_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_005576.3
RefSeq - NG_012244.1
RefSeq - 92859871
RefSeq - XP_011519863.1
RefSeq - 767984140
RefSeq - NC_000015.10
RefSeq - XR_931827.2
RefSeq - NM_001142861.2
RefSeq - NM_005585.4
RefSeq - NR_027654.1
RefSeq - XM_011521561.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000137834 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001657 ureteric bud development IEA
 biological_processGO:0003148 outflow tract septum morphogenesis ISS
 biological_processGO:0003180 aortic valve morphogenesis IMP
 biological_processGO:0003183 mitral valve morphogenesis ISS
 biological_processGO:0003184 pulmonary valve morphogenesis ISS
 biological_processGO:0003281 ventricular septum development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006955 immune response IMP
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0007352 zygotic specification of dorsal/ventral axis IMP
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0010991 negative regulation of SMAD protein complex assembly IDA
 biological_processGO:0030279 negative regulation of ossification ISS
 biological_processGO:0030509 BMP signaling pathway TAS
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0030514 negative regulation of BMP signaling pathway IMP
 biological_processGO:0031589 cell-substrate adhesion IMP
 biological_processGO:0034616 response to laminar fluid shear stress IEP
 biological_processGO:0035904 aorta development IEA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045444 fat cell differentiation IDA
 biological_processGO:0045668 negative regulation of osteoblast differentiation IMP
 biological_processGO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation IMP
 biological_processGO:0060976 coronary vasculature development IEA
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity IMP
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0034713 type I transforming growth factor beta receptor binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070410 co-SMAD binding IPI
 molecular_functionGO:0070411 I-SMAD binding IPI
 molecular_functionGO:0070412 R-SMAD binding IPI
 molecular_functionGO:0070698 type I activin receptor binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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