4137


Homo sapiens (NCBI)

Features
Gene ID: 4137
  
Biological name :
  
Synonyms : DDPAC|FTDP-17|MAPTL|MSTD|MTBT1|MTBT2|PPND|PPP1R103|TAU / MAPT / microtubule associated protein tau
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203928_x_at (Human Genome U133 Plus 2.0 Array)   203929_s_at (Human Genome U133 Plus 2.0 Array)   203930_s_at (Human Genome U133 Plus 2.0 Array)   206401_s_at (Human Genome U133 Plus 2.0 Array)   225379_at (Human Genome U133 Plus 2.0 Array)   233117_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_005257428.1
RefSeq - 294862258
RefSeq - 294862261
RefSeq - 322303720
RefSeq - 322303747
RefSeq - 530412219
RefSeq - 530412223
RefSeq - 530412225
RefSeq - 530412227
RefSeq - 530412229
RefSeq - 530412231
RefSeq - 530412233
RefSeq - 530412235
RefSeq - 530412237
RefSeq - 6754638
RefSeq - 8400711
RefSeq - 8400715
RefSeq - NC_000017.11
RefSeq - NG_007398.1
RefSeq - NP_001190180.1
RefSeq - NP_001190181.1
RefSeq - NP_005901.2
RefSeq - NP_058518.1
RefSeq - NP_058519.3
RefSeq - NP_058525.1
RefSeq - NT_167251.2
RefSeq - NT_187663.1
RefSeq - XP_005257419.1
RefSeq - XP_005257421.1
RefSeq - XP_005257422.1
RefSeq - XP_005257423.1
RefSeq - XP_005257424.1
RefSeq - XP_005257425.1
RefSeq - XP_005257426.1
RefSeq - XP_005257427.1
RefSeq - 178557736
RefSeq - NP_001116538.2
RefSeq - NP_001116539.1
RefSeq - NM_001123066.3
RefSeq - NM_001123067.3
RefSeq - NM_001203251.1
RefSeq - NM_001203252.1
RefSeq - NM_005910.5
RefSeq - NM_016834.4
RefSeq - NM_016835.4
RefSeq - NM_016841.4
RefSeq - XM_005257371.4
RefSeq - XM_005257362.4
RefSeq - XM_005257364.4
RefSeq - XM_005257365.4
RefSeq - XM_005257366.3
RefSeq - XM_005257367.4
RefSeq - XM_005257368.4
RefSeq - XM_005257369.4
RefSeq - XM_005257370.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000186868 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization NAS
 biological_processGO:0001774 microglial cell activation TAS
 biological_processGO:0006475 internal protein amino acid acetylation TAS
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process TAS
 biological_processGO:0007267 cell-cell signaling NAS
 biological_processGO:0007613 memory IMP
 biological_processGO:0010288 response to lead ion ISS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010506 regulation of autophagy IGI
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0010917 negative regulation of mitochondrial membrane potential IMP
 biological_processGO:0016072 rRNA metabolic process TAS
 biological_processGO:0019896 axonal transport of mitochondrion TAS
 biological_processGO:0021954 central nervous system neuron development TAS
 biological_processGO:0031110 regulation of microtubule polymerization or depolymerization IMP
 biological_processGO:0031113 regulation of microtubule polymerization TAS
 biological_processGO:0031116 positive regulation of microtubule polymerization IDA
 biological_processGO:0031122 cytoplasmic microtubule organization TAS
 biological_processGO:0031175 neuron projection development TAS
 biological_processGO:0032930 positive regulation of superoxide anion generation IMP
 biological_processGO:0033044 regulation of chromosome organization TAS
 biological_processGO:0033673 negative regulation of kinase activity IMP
 biological_processGO:0034063 stress granule assembly TAS
 biological_processGO:0034605 cellular response to heat TAS
 biological_processGO:0034614 cellular response to reactive oxygen species TAS
 biological_processGO:0045773 positive regulation of axon extension IDA
 biological_processGO:0046785 microtubule polymerization TAS
 biological_processGO:0048143 astrocyte activation TAS
 biological_processGO:0048167 regulation of synaptic plasticity TAS
 biological_processGO:0048312 intracellular distribution of mitochondria IMP
 biological_processGO:0048699 generation of neurons NAS
 biological_processGO:0050808 synapse organization IMP
 biological_processGO:0050848 regulation of calcium-mediated signaling IDA
 biological_processGO:0051259 protein complex oligomerization TAS
 biological_processGO:0061564 axon development TAS
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization TAS
 biological_processGO:0072386 plus-end-directed organelle transport along microtubule TAS
 biological_processGO:0090140 regulation of mitochondrial fission IC
 biological_processGO:0090258 negative regulation of mitochondrial fission IMP
 biological_processGO:0097435 supramolecular fiber organization IMP
 biological_processGO:0098930 axonal transport TAS
 biological_processGO:1900034 regulation of cellular response to heat IMP
 biological_processGO:1900452 regulation of long term synaptic depression TAS
 biological_processGO:1901216 positive regulation of neuron death IMP
 biological_processGO:1902474 positive regulation of protein localization to synapse IMP
 biological_processGO:1902988 neurofibrillary tangle assembly NAS
 biological_processGO:1903748 negative regulation of establishment of protein localization to mitochondrion IMP
 biological_processGO:1903829 positive regulation of cellular protein localization IMP
 biological_processGO:1904428 negative regulation of tubulin deacetylation TAS
 biological_processGO:1905689 positive regulation of diacylglycerol kinase activity ISS
 biological_processGO:1990000 amyloid fibril formation IMP
 biological_processGO:1990090 cellular response to nerve growth factor stimulus TAS
 biological_processGO:1990416 cellular response to brain-derived neurotrophic factor stimulus TAS
 biological_processGO:2001020 regulation of response to DNA damage stimulus IMP
 cellular_componentGO:0005576 extracellular region NAS
 cellular_componentGO:0005622 intracellular TAS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005874 microtubule ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0015630 microtubule cytoskeleton NAS
 cellular_componentGO:0016020 membrane IMP
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0030424 axon TAS
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0030426 growth cone IDA
 cellular_componentGO:0030673 axolemma IDA
 cellular_componentGO:0034399 nuclear periphery IDA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IDA
 cellular_componentGO:0036477 somatodendritic compartment TAS
 cellular_componentGO:0043005 neuron projection IBA
 cellular_componentGO:0043025 neuronal cell body IMP
 cellular_componentGO:0043197 dendritic spine TAS
 cellular_componentGO:0044297 cell body ISS
 cellular_componentGO:0044304 main axon ISS
 cellular_componentGO:0045121 membrane raft ISS
 cellular_componentGO:0045298 tubulin complex IDA
 cellular_componentGO:0097386 glial cell projection ISS
 cellular_componentGO:0097418 neurofibrillary tangle NAS
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003680 AT DNA binding TAS
 molecular_functionGO:0003690 double-stranded DNA binding TAS
 molecular_functionGO:0003697 single-stranded DNA binding TAS
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003779 actin binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding TAS
 molecular_functionGO:0017124 SH3 domain binding IPI
 molecular_functionGO:0019899 enzyme binding ISS
 molecular_functionGO:0019901 protein kinase binding ISS
 molecular_functionGO:0030674 protein binding, bridging TAS
 molecular_functionGO:0034185 apolipoprotein binding IPI
 molecular_functionGO:0034452 dynactin binding TAS
 molecular_functionGO:0035091 phosphatidylinositol binding TAS
 molecular_functionGO:0042802 identical protein binding IMP
 molecular_functionGO:0042803 protein homodimerization activity IMP
 molecular_functionGO:0043565 sequence-specific DNA binding TAS
 molecular_functionGO:0048018 receptor ligand activity IDA
 molecular_functionGO:0051087 chaperone binding IPI
 molecular_functionGO:0051721 protein phosphatase 2A binding TAS
 molecular_functionGO:0051879 Hsp90 protein binding IPI
 molecular_functionGO:0071813 lipoprotein particle binding IPI
 molecular_functionGO:0099077 histone-dependent DNA binding TAS
 molecular_functionGO:0099609 microtubule lateral binding IMP
 molecular_functionGO:1902936 phosphatidylinositol bisphosphate binding TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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