4193


Homo sapiens (NCBI)

Features
Gene ID: 4193
  
Biological name :
  
Synonyms : ACTFS|HDMX|hdm2 / MDM2 / MDM2 proto-oncogene
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205385_at (Human Genome U133 Plus 2.0 Array)   205386_s_at (Human Genome U133 Plus 2.0 Array)   211832_s_at (Human Genome U133 Plus 2.0 Array)   217373_x_at (Human Genome U133 Plus 2.0 Array)   217542_at (Human Genome U133 Plus 2.0 Array)   225160_x_at (Human Genome U133 Plus 2.0 Array)   229711_s_at (Human Genome U133 Plus 2.0 Array)   237891_at (Human Genome U133 Plus 2.0 Array)   244616_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 223890201
RefSeq - 223890205
RefSeq - 223890207
RefSeq - 510937018
RefSeq - 530400249
RefSeq - 578823728
RefSeq - 578823730
RefSeq - 89993689
RefSeq - NC_000012.12
RefSeq - NG_016708.1
RefSeq - NP_001138809.1
RefSeq - NP_001138811.1
RefSeq - NP_001138812.1
RefSeq - NP_001265391.1
RefSeq - NP_002383.2
RefSeq - XP_005268929.1
RefSeq - XP_006719462.1
RefSeq - XP_006719463.1
RefSeq - NM_006880.2
RefSeq - NM_006881.3
RefSeq - NM_006882.3
RefSeq - NM_032739.1
RefSeq - XM_006719399.4
RefSeq - XM_006719400.4
RefSeq - XM_005268872.5
RefSeq - NM_001145336.1
RefSeq - NM_001145337.2
RefSeq - NM_001145339.2
RefSeq - NM_001145340.2
RefSeq - NM_001278462.1
RefSeq - NM_002392.5
RefSeq - NM_006878.3
RefSeq - NM_006879.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000135679 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001568 blood vessel development IEA
 biological_processGO:0001974 blood vessel remodeling IEA
 biological_processGO:0002027 regulation of heart rate IEA
 biological_processGO:0003181 atrioventricular valve morphogenesis IEA
 biological_processGO:0003203 endocardial cushion morphogenesis IEA
 biological_processGO:0003281 ventricular septum development IEA
 biological_processGO:0003283 atrial septum development IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0007089 traversing start control point of mitotic cell cycle IEA
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0010039 response to iron ion IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010955 negative regulation of protein processing IEA
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0016925 protein sumoylation IEA
 biological_processGO:0018205 peptidyl-lysine modification IMP
 biological_processGO:0031648 protein destabilization IMP
 biological_processGO:0032026 response to magnesium ion IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0034504 protein localization to nucleus IDA
 biological_processGO:0036369 transcription factor catabolic process TAS
 biological_processGO:0042176 regulation of protein catabolic process IDA
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator IDA
 biological_processGO:0045184 establishment of protein localization IDA
 biological_processGO:0045472 response to ether IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045931 positive regulation of mitotic cell cycle IMP
 biological_processGO:0046677 response to antibiotic IEP
 biological_processGO:0046827 positive regulation of protein export from nucleus IEA
 biological_processGO:0048545 response to steroid hormone IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IMP
 biological_processGO:0051865 protein autoubiquitination IMP
 biological_processGO:0060411 cardiac septum morphogenesis IEA
 biological_processGO:0065003 protein-containing complex assembly IDA
 biological_processGO:0070301 cellular response to hydrogen peroxide IEA
 biological_processGO:0071157 negative regulation of cell cycle arrest IDA
 biological_processGO:0071301 cellular response to vitamin B1 IEA
 biological_processGO:0071312 cellular response to alkaloid IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 biological_processGO:0071375 cellular response to peptide hormone stimulus IEA
 biological_processGO:0071391 cellular response to estrogen stimulus IEA
 biological_processGO:0071456 cellular response to hypoxia IEP
 biological_processGO:0071480 cellular response to gamma radiation IDA
 biological_processGO:0071494 cellular response to UV-C IEA
 biological_processGO:0072717 cellular response to actinomycin D IDA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 biological_processGO:1901797 negative regulation of signal transduction by p53 class mediator IDA
 biological_processGO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator IMP
 biological_processGO:1904404 response to formaldehyde IEA
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:1904754 positive regulation of vascular associated smooth muscle cell migration IEA
 biological_processGO:1990000 amyloid fibril formation IMP
 biological_processGO:1990785 response to water-immersion restraint stress IEA
 cellular_componentGO:0005634 nucleus IMP
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IMP
 cellular_componentGO:0005737 cytoplasm IMP
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0002039 p53 binding IPI
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008097 5S rRNA binding IDA
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0016874 ligase activity IDA
 molecular_functionGO:0019789 SUMO transferase activity EXP
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0033612 receptor serine/threonine kinase binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042975 peroxisome proliferator activated receptor binding IEA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IDA
 molecular_functionGO:0047485 protein N-terminus binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity TAS
 molecular_functionGO:0061663 NEDD8 ligase activity IMP
 molecular_functionGO:0097110 scaffold protein binding IEA
 molecular_functionGO:0097718 disordered domain specific binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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