4205


Homo sapiens (NCBI)
bindingtranscriptionrnapolymeraseiifactorsequence-specificactivitydnaregulationmusclecardiacproteincascadedevelopmentchromatinproximalpromotertranscriptionalactivatoractivatingdistalenhancerhistonemitochondrialgenomemaintenancemapkdna-templatedapoptotic

Features
Gene ID: 4205
  
Biological name :
  
Synonyms : ADCAD1|RSRFC4|RSRFC9|mef2 / MEF2A / myocyte enhancer factor 2A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208328_s_at (Human Genome U133 Plus 2.0 Array)   212535_at (Human Genome U133 Plus 2.0 Array)   214684_at (Human Genome U133 Plus 2.0 Array)   242176_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 767984182
RefSeq - 1034590628
RefSeq - 1034590633
RefSeq - 1034590637
RefSeq - 1034590642
RefSeq - 1034590645
RefSeq - 1034590647
RefSeq - 1034590649
RefSeq - 1034590651
RefSeq - 1034590653
RefSeq - 1034590655
RefSeq - 1034590657
RefSeq - 1034590661
RefSeq - 1034590663
RefSeq - 1208397259
RefSeq - 1208397261
RefSeq - 1208397263
RefSeq - 1208397265
RefSeq - 1208397267
RefSeq - 195972799
RefSeq - 195972801
RefSeq - 195972803
RefSeq - 195972805
RefSeq - 284807140
RefSeq - 530407143
RefSeq - 530407145
RefSeq - 767984170
RefSeq - 767984172
RefSeq - 767984174
RefSeq - 767984180
RefSeq - 1034590626
RefSeq - 767984184
RefSeq - 767984186
RefSeq - 767984190
RefSeq - 767984192
RefSeq - 767984194
RefSeq - 767984198
RefSeq - 767984200
RefSeq - 767984202
RefSeq - 767984208
RefSeq - 984290559
RefSeq - NC_000015.10
RefSeq - NG_016443.2
RefSeq - NP_001124398.1
RefSeq - NP_001124399.1
RefSeq - NP_001124400.1
RefSeq - NP_001165365.1
RefSeq - NP_001306135.1
RefSeq - NP_001339543.1
RefSeq - NP_001339544.1
RefSeq - NP_001339545.1
RefSeq - NP_001339546.1
RefSeq - NP_001339547.1
RefSeq - NP_005578.2
RefSeq - XP_005254972.1
RefSeq - XP_005254973.1
RefSeq - XP_011519873.1
RefSeq - XP_011519874.1
RefSeq - XP_011519875.1
RefSeq - XP_011519878.1
RefSeq - XP_011519879.1
RefSeq - XP_011519880.1
RefSeq - XP_011519881.1
RefSeq - XP_011519883.1
RefSeq - XP_011519884.1
RefSeq - XP_011519885.1
RefSeq - XP_011519887.1
RefSeq - XP_011519888.1
RefSeq - XP_011519889.1
RefSeq - XP_011519892.1
RefSeq - XP_016877679.1
RefSeq - XP_016877680.1
RefSeq - XP_016877681.1
RefSeq - XP_016877683.1
RefSeq - XP_016877684.1
RefSeq - XP_016877685.1
RefSeq - XP_016877686.1
RefSeq - XP_016877687.1
RefSeq - XP_016877688.1
RefSeq - XP_016877689.1
RefSeq - XP_016877690.1
RefSeq - XP_016877691.1
RefSeq - XP_016877692.1
RefSeq - XP_016877693.1
RefSeq - XM_017022194.1
RefSeq - NM_001130926.2
RefSeq - NM_001130927.2
RefSeq - NM_001130928.2
RefSeq - NM_001171894.2
RefSeq - NM_001319206.1
RefSeq - NM_001352614.1
RefSeq - NM_001352615.1
RefSeq - NM_001352616.1
RefSeq - NM_001352617.1
RefSeq - NM_001352618.1
RefSeq - NM_005587.3
RefSeq - XM_017022195.1
RefSeq - XM_017022196.1
RefSeq - XM_017022197.2
RefSeq - XM_017022198.2
RefSeq - XM_017022199.1
RefSeq - XM_017022200.1
RefSeq - XM_017022201.1
RefSeq - XM_017022202.1
RefSeq - XM_017022203.1
RefSeq - XM_017022204.1
RefSeq - XR_001751289.1
RefSeq - XM_005254915.2
RefSeq - XM_005254916.3
RefSeq - XM_011521571.3
RefSeq - XM_011521572.2
RefSeq - XM_011521573.2
RefSeq - XM_011521576.2
RefSeq - XM_011521577.2
RefSeq - XM_011521578.2
RefSeq - XM_011521579.2
RefSeq - XM_011521581.3
RefSeq - XM_011521582.2
RefSeq - XM_011521583.2
RefSeq - XM_011521585.2
RefSeq - XM_011521586.2
RefSeq - XM_011521587.2
RefSeq - XM_011521590.2
RefSeq - XM_017022190.1
RefSeq - XM_017022191.1
RefSeq - XM_017022192.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000068305 to get all the annotations available for this gene.


Gene Ontology (GO)
cellular component organizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathanatomical structure developmentsystem processestablishment of localizationcellular localizationcellular developmental processcellular component biogenesisactin filament-based processmulticellular organismal signalingresponse to chemicalcellular component organizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathanatomical structure developmentsystem processestablishment of localizationcellular localizationcellular developmental processcellular component biogenesisactin filament-based processmulticellular organismal signalingresponse to chemicalcellular component organizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathanatomical structure developmentsystem processestablishment of localizationcellular localizationcellular developmental processcellular component biogenesisactin filament-based processmulticellular organismal signalingresponse to chemicalcellular component organizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathanatomical structure developmentsystem processestablishment of localizationcellular localizationcellular developmental processcellular component biogenesisactin filament-based processmulticellular organismal signalingresponse to chemicalcellular component organizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathanatomical structure developmentsystem processestablishment of localizationcellular localizationcellular developmental processcellular component biogenesisactin filament-based processmulticellular organismal signalingresponse to chemicalcellular component organizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathanatomical structure developmentsystem processestablishment of localizationcellular localizationcellular developmental processcellular component biogenesisactin filament-based processmulticellular organismal signalingresponse to chemicalcellular component organizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathanatomical structure developmentsystem processestablishment of localizationcellular localizationcellular developmental processcellular component biogenesisactin filament-based processmulticellular organismal signalingresponse to chemicalcellular component organizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathanatomical structure developmentsystem processestablishment of localizationcellular localizationcellular developmental processcellular component biogenesisactin filament-based processmulticellular organismal signalingresponse to chemicalcellular component organizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathanatomical structure developmentsystem processestablishment of localizationcellular localizationcellular developmental processcellular component biogenesisactin filament-based processmulticellular organismal signalingresponse to chemicalcellular component organizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathanatomical structure developmentsystem processestablishment of localizationcellular localizationcellular developmental processcellular component biogenesisactin filament-based processmulticellular organismal signalingresponse to chemicalcellulacellular component organizationnitrogenitrogen compound metabolic processbiosyntbiosynthetic processcellulacellular metabolic processprimaryprimary metabolic processorganicorganic substance metabolic processcell cocell communicationcellulacellular response to stimuluscell decell deathanatomianatomical structure developmentsystem system processestabliestablishment of localizationcellulacellular localizationcellulacellular developmental processcellulacellular component biogenesisactin factin filament-based processmulticemulticellular organismal signalingresponsresponse to chemical
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingchromatin bindingtranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingchromatin bindingtranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingchromatin bindingtranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingchromatin bindingtranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingchromatin bindingtranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingchromatin bindingtranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingchromatin bindingtranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingchromatin bindingtranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingchromatin bindingtranscription coregulator activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingchromatin bindingtranscription coregulator activityorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingDNA-binding transcriptiDNA-binding transcription factor activityprotein bindingprotein bindingchromatin bindingchromatin bindingtranscription coregulattranscription coregulator activity
cellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000002 mitochondrial genome maintenance ISS
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0000165 MAPK cascade IDA
 biological_processGO:0006351 transcription, DNA-templated IDA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007507 heart development IEP
 biological_processGO:0007517 muscle organ development NAS
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy IGI
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0048311 mitochondrion distribution ISS
 biological_processGO:0048813 dendrite morphogenesis ISS
 biological_processGO:0051149 positive regulation of muscle cell differentiation TAS
 biological_processGO:0055005 ventricular cardiac myofibril assembly ISS
 biological_processGO:0061337 cardiac conduction ISS
 biological_processGO:0070375 ERK5 cascade IMP
 biological_processGO:0071277 cellular response to calcium ion IDA
 cellular_componentGO:0000790 nuclear chromatin ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IPI
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IBA
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IBA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0033613 activating transcription factor binding IPI
 molecular_functionGO:0035035 histone acetyltransferase binding IPI
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046332 SMAD binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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