4297


Homo sapiens (NCBI)

Features
Gene ID: 4297
  
Biological name :
  
Synonyms : ALL-1|CXXC7|HRX|HTRX1|MLL|MLL1|MLL1A|TRX1|WDSTS / KMT2A / lysine methyltransferase 2A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1559856_s_at (Human Genome U133 Plus 2.0 Array)   1565436_s_at (Human Genome U133 Plus 2.0 Array)   212076_at (Human Genome U133 Plus 2.0 Array)   212078_s_at (Human Genome U133 Plus 2.0 Array)   212079_s_at (Human Genome U133 Plus 2.0 Array)   212080_at (Human Genome U133 Plus 2.0 Array)   216624_s_at (Human Genome U133 Plus 2.0 Array)   220546_at (Human Genome U133 Plus 2.0 Array)   226981_at (Human Genome U133 Plus 2.0 Array)   229935_s_at (Human Genome U133 Plus 2.0 Array)   244110_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_011541135.1
RefSeq - 56550039
RefSeq - 767970167
RefSeq - 767970169
RefSeq - 767970171
RefSeq - 767970175
RefSeq - 767970177
RefSeq - NC_000011.10
RefSeq - NG_027813.1
RefSeq - NP_001184033.1
RefSeq - NP_005924.2
RefSeq - XP_006718902.2
RefSeq - XP_011541131.1
RefSeq - XP_011541132.1
RefSeq - XP_011541133.1
RefSeq - 308199413
RefSeq - XM_011542830.2
RefSeq - NM_001197104.1
RefSeq - NM_005933.3
RefSeq - NM_024891.2
RefSeq - XM_011542831.2
RefSeq - XM_011542833.2
RefSeq - XM_006718839.3
RefSeq - XM_011542829.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000118058 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006306 DNA methylation IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0018026 peptidyl-lysine monomethylation IEA
 biological_processGO:0032411 positive regulation of transporter activity IMP
 biological_processGO:0032922 circadian regulation of gene expression ISS
 biological_processGO:0035162 embryonic hemopoiesis TAS
 biological_processGO:0035640 exploration behavior IEA
 biological_processGO:0035864 response to potassium ion IEA
 biological_processGO:0043984 histone H4-K16 acetylation IMP
 biological_processGO:0044648 histone H3-K4 dimethylation IEA
 biological_processGO:0045652 regulation of megakaryocyte differentiation TAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048172 regulation of short-term neuronal synaptic plasticity IEA
 biological_processGO:0048536 spleen development IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0051568 histone H3-K4 methylation IMP
 biological_processGO:0051571 positive regulation of histone H3-K4 methylation ISS
 biological_processGO:0051899 membrane depolarization IEA
 biological_processGO:0060216 definitive hemopoiesis IEA
 biological_processGO:0065003 protein-containing complex assembly IDA
 biological_processGO:0071440 regulation of histone H3-K14 acetylation ISS
 biological_processGO:0080182 histone H3-K4 trimethylation IDA
 biological_processGO:1901674 regulation of histone H3-K27 acetylation IEA
 biological_processGO:1902036 regulation of hematopoietic stem cell differentiation TAS
 biological_processGO:1905642 negative regulation of DNA methylation IMP
 biological_processGO:2000615 regulation of histone H3-K9 acetylation ISS
 biological_processGO:2001040 positive regulation of cellular response to drug IMP
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0035097 histone methyltransferase complex IDA
 cellular_componentGO:0071339 MLL1 complex IDA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding ISS
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003680 AT DNA binding NAS
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity TAS
 molecular_functionGO:0042800 histone methyltransferase activity (H3-K4 specific) IMP
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0045322 unmethylated CpG binding IDA
 molecular_functionGO:0070577 lysine-acetylated histone binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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